Rchr
J-GLOBAL ID:200901067159712821
Update date: Nov. 16, 2023
Okayasu Ryuichi
オカヤス リュウイチ | Okayasu Ryuichi
Affiliation and department:
Job title:
Collaborative Researcher
Other affiliations (1):
-
Colorado State University
Faculty Affiliate
Research field (3):
Radiology
, Environmental policy and society
, Environmental impact assessment
Research keywords (33):
17AAG
, DNA DSB修復
, Rad51
, 放射線増感材
, 非相同末端結合
, DNA ligase IV
, 放射線増感剤
, 癌細胞
, non-homologous end joining
, アポトーシス
, 相同組み換え修復
, BRCA2
, HSP90阻害剤
, 放射線抵抗性
, DNA-PKcs
, siRNA
, RNA干渉
, Homologous recombination repair
, 正常細胞
, RNA工学
, RNAアプタマー
, タンパク質リン酸化
, 生理活性物質
, 分子標的創薬
, 放射線治療生物学
, 癌治療
, DNA修復
, 遺伝子修復
, 腫よう
, 放射線生物
, DNA Repair
, Cancer Biology
, Radiation Biology
Papers (108):
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Takeshi Yasuda, Wataru Kagawa, Tomoo Ogi, Takamitsu A Kato, Takehiro Suzuki, Naoshi Dohmae, Kazuya Takizawa, Yuka Nakazawa, Matthew D Genet, Mika Saotome, et al. Novel function of HATs and HDACs in homologous recombination through acetylation of human RAD52 at double-strand break sites. PLoS genetics. 2018. 14. 3. e1007277
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Shigeaki Sunada, Hirokazu Hirakawa, Akira Fujimori, Mitsuru Uesaka, Ryuichi Okayasu. Oxygen Enhancement Ratio in Radiation-Induced Initial DSBs by an Optimized Flow Cytometry-based Gamma-H2AX Analysis in A549 Human Cancer Cells. RADIATION RESEARCH. 2017. 188. 5. 591-594
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Christopher P. Allen, Hirokazu Hirakawa, Nakako Izumi Nakajima, Sophia Moore, Jingyi Nie, Neelam Sharma, Mayumi Sugiura, Yuko Hoki, Ryoko Araki, Masumi Abe, et al. Low- and High-LET Ionizing Radiation Induces Delayed Homologous Recombination that Persists for Two Weeks before Resolving. RADIATION RESEARCH. 2017. 188. 1. 82-93
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Ralf Moeller, Marina Raguse, Stefan Leuko, Thomas Berger, Christine Elisabeth Hellweg, Akira Fujimori, Ryuichi Okayasu, Gerda Horneck. STARLIFE-An International Campaign to Study the Role of Galactic Cosmic Radiation in Astrobiological Model Systems. ASTROBIOLOGY. 2017. 17. 2. 101-109
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Younghyun Lee, Shigeaki Sunada, Hirokazu Hirakawa, Akira Fujimori, Jac A. Nickoloff, Ryuichi Okayasu. TAS-116, a Novel Hsp90 Inhibitor, Selectively Enhances Radiosensitivity of Human Cancer Cells to X-rays and Carbon Ion Radiation. MOLECULAR CANCER THERAPEUTICS. 2017. 16. 1. 16-24
more...
MISC (50):
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Okayasu, R., Suetomi, K., and Takahashi, S. Suppression of DNA double strand break repair by RNAi technology: An application to radiation therapy?. Radiat. Biol. Res. Communication (in Japanese). 2005. 40, 260-269
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Okayasu, R., Okada, M, Okabe, A., Noguchi, M., Takakura, K. and Takahashi, S. Heavy ion radiation induces complex DNA damage that cannot be efficiently repaired by non-homologous end joining. Radiat. Res. 2005
-
Fujimori, A., Okayasu, R., Ishihara, H., Yoshida, S., Eguchi-Kasai, K., Nojima, K., Ebisawa, S., Takahashi, S.Extremely low-dose ionizing radiation upregulates CXC chemokines in normal human fibroblasts. Cancer Res. 2005. 65, 10159-10163
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Kawata, T., Ito, H., Saito, M., Uno, T., Okayasu, R., Liu, C., Kan’o, M., George, K. And Cucinotta, F.A. Caffeine sensitizes non-dividing human fibroblasts to X-rays by inducing high frequency of misrepair. Radiat. Res. 2005. 164, 509-513
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Iimuro, R, Takahashi, S, Ito, H, Kubota, Y, Suetomi, K, Sato, H, Okayasu, R. Radio-sensitivity of the cells from amyotrophic lateral sclerosis model mice transfected with human mutant SOD1. J. Radiat. Res. 2005. 46, 67-73
more...
Works (2):
-
タバコ発癌とDNA二重鎖切断修復
2002 - 2004
-
DNA Double Strard Break Repair in Tobacco Carcinogenesis
2002 - 2004
Education (4):
- - 1987 コロラド州立大学 放射線及び放射線生物学(Radiology & Radiation Biology) 放射線生物学(Radiation Biology)
- - 1987 Colorado State University Radiology & Radiation Biology Radiation Biology
- - 1974 Tokyo University of Science
- - 1974 Tokyo University of Science Faculty of Science Physics
Professional career (1):
- Ph.D.(Doctor of Philosophy) (Colorado State University(USA))
Work history (12):
- 2016/04 - 現在 放射線医学総合研究所 協力研究員・客員研究員
- 2014/04 - 2016/03 National Institute of Radiological Sciences Res Center for Radiation Protection Senior Researcher
- 2011/04 - 2014/03 National Institute of Radiological Sciences International Open Laboratory Scientific Secretary/Research Sceintist
- 2006/04 - 2011/03 National Institute of Radiological Sciences Heavy-ion Radiobiology Res. Group Director
- 2005 - 2006 放射線医学総合研究所 プロジェクトリーダー(宇宙放射線防護P)
- 2002 - 2005 放射線医学総合研究所 チームリーダー
- 1998 - 2002 コロラド州立大学 助教授
- 1998 - 2002 Assistant Professor, Colorado State University
- 2002 - - National Institute of Radiological Science, Team Leader
- 1995 - 1998 テキサス大学医学部 助教授
- 1995 - 1998 Assistant Professor, University of Texas Medical
- Branch
Show all
Committee career (2):
- 2005 - 放射線影響学会 評議員
- 放射線学会(Radiation Research Society) 正会員
Association Membership(s) (11):
アメリカ科学振興協会(AAAS)
, 国際癌治療増感研究協会
, 日本医学放射線学会生物部会
, 放射線生物研究会
, 日本癌学会
, 放射線影響学会
, 放射線学会(Radiation Research Society)
, アメリカ癌学会
, Japan Radiation Research Society
, Radiation Research Society
, American Association for Cancer Research
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