Research theme for competitive and other funds (7):
2016 - 2022 Elucidation of Opioid Cross-Tolerance in Cancer Pain Models
2012 - 2015 Prognisis after anaogesic treatment for cancer pain
2010 - 2011 Elucidation of the relation between mu opioid receptor internalization and analgesia induced by oxycodone
2009 - 2011 Clarify the role of mu receptor endocytosis in spinal analgesia and opioid tolerance
2005 - 2006 微量フェンタニルによるモルヒネ耐性形成の抑制の誘導
2001 - オピオイド鎮痛における細胞内情報伝達
2001 - -
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Papers (17):
Toshihiko Nakatani, Kazuhito Shiosakai, Tatsuya Hashimoto, Masao Shionoya, Takaaki Akasaka, Kaoru Toyama, Hitoshi Ishizuka, Yoji Saito. Steady-State Pharmacokinetics of Intravenous Hydromorphone in Japanese Patients With Renal Impairment and Cancer Pain. Journal of Palliative Medicine. 2023. 26. 6. 768-775
Hideaki Mori, Tatsuya Hashimoto, Tetsuro Nikai, Motohide Furuya, Mai Hattori, Yukiko Katsube, Yoji Saito. Long-Term Exposure to Morphine Induces Cross-Tolerance to Acute Antinociceptive Effect of Remifentanil on Somatic and Visceral Stimuli in Rats. Journal of Pain Research. 2022. Volume 15. 4047-4054
Tatsuya Hashimoto, Hirokazu Mishima, Chika Sakai, Yuichi Koretaka, Yoji Saito. An exploratory study of factors associated with long-term, high-dose opioid prescription in cancer patients in Japan based on a medical claims database. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. 2022. 30. 8. 6879-6888
Sutou Ichiro, Nakatani Toshihiko, Hashimoto Tatsuya, Saito Yoji. Three Cases of Neuropathic Pain With Effective Pain Relief After Switching From Hydromorphone to Oxycodone(和訳中). Shimane Journal of Medical Science. 2021. 38. 3. 99-105
Tsunetaka Kijima, Ryoji Hyakudomi, Tatsuya Hashimoto, Akari Kusaka, Toshihiko Nakatani, Yutaka Ishibashi. Adhesion-induced chronic abdominal pain: a case report on the diagnostic value of Carnett's test. Journal of medical case reports. 2019. 13. 1. 93-93
Tatsuhito Miyamoto, Toshinao Tomiyama, Yuko Watanabe, Tatsuya Hashimoto. Pruritus Caused by the Change in Hydromorphone Formulation Disappeared after Switching to the Fentanyl Patch: A Case Report. 2024. 19. 1. 67-70