Research field (3)：
Clinical pharmacy
, Pathobiochemistry
, Medical biochemistry
Research keywords (7)：
再生・増殖因子
, レクチン
, ランゲルハンス島
, 糖鎖
, 糖尿病
, Regenerative Medicine
, Diabetes
Research theme for competitive and other funds (28)：
2022 - 2025 肥満症の治療と健康寿命の延伸を目指した褐色脂肪細胞機能活性化の試み
2008 - 2010 Reduceds β-cell proliferation and impaired glucose tolerance in pancreatics β-cell specific Extl3 knockout mice.
2006 - 2007 Targeted disruption of the Reg protein receptor gene : The relationship of the Reg-Reg receptor system with pancreatic 13-cell replication.
2005 - 2006 Regulation of the CD38-cyclic ADP-ribose signal system by tissue-specific slicing of ryanodine receptor
2000 - 2002 Physiological and pathological Roles of the CD38/cyclic ADP-ribose signal system in cardiac myocytes
2000 - 2001 Structure and transcriptional regulation of gene encoding human FK506 binding protein 12 and 12.6
1999 - 2001 Targeted disruption of all the Reg family genes: A new animal model for regeneration deficient disorders
1998 - 1999 Mechanisms for transcriptional activation of Reg (Regenerating gene)
1996 - 1998 Generation of animal model of diabetes by disrupting the ADP-ribosyl cyclase (CD38) gene
1996 - 1997 Study for the molecular pathogenesis of the idiopathic chronic pancreatitis, especially familial pancreatitis
1996 - 1997 Targeted disruption of Reg gene : A new animal model of diabetes and pancreatitis.
1991 - 1993 Production of the two enzymes concerned in peptide C-terminal alpha-amidation by genetic engineering and in vitro reconstitution of peptide C-terminal alpha-amidation reaction
1988 - 1989 膵ポリペプチド遺伝子の構造と発現調節
インスリン産生膵β細胞の機能と増殖機構に関する研究
Function and proliferation of insulin-producing pancreatic beta cell
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Papers (79)：
OHASHI Kazuaki, OHASHI Hiroyoshi, YE Bin, NATA Koji. New Systematic Position of Desmodiastrum (Leguminosae Tribe Desmodieae). The Journal of Japanese Botany. 2022. 97. 3. 131-144
Yuriko Matsushita, Yutaka Hasegawa, Noriko Takebe, Ken Onodera, Masaharu Shozushima, Tomoyasu Oda, Kan Nagasawa, Hiroyuki Honma, Koji Nata, Akira Sasaki, et al. Serum C-X-C motif chemokine ligand 14 levels are associated with serum C-peptide and fatty liver index in type 2 diabetes mellitus patients. Journal of diabetes investigation. 2021. 12. 6. 1042-1049
Mami Obara, Sachiko Sato, Kumi Takahashi, Yukiko Kondo, Masamichi Hirose, Koji Nata, Eichi Taira. Expression of cell adhesion molecule, Gicerin/CD146 during the formation of heart and in the cardiac hypertrophy. Molecular and cellular biochemistry. 2021. 476. 5. 2021-2028
Yutaka Hasegawa, Yoshihiko Takahashi, Yuichiro Kezuka, Wataru Obara, Yoichiro Kato, Shukuko Tamura, Ken Onodera, Toshie Segawa, Tomoyasu Oda, Marino Sato, et al. Identification and Analysis of a Novel NR0B1 Mutation in Late-Onset Adrenal Hypoplasia Congenita and Hypogonadism. Journal of the Endocrine Society. 2021. 5. 2. bvaa176
Kazuaki Ohashi, Hiroyoshi Ohashi, Koji Nata, P. Souladeth, S. Tagane. A New Species and a New Combination of Grona with a List of Desmodium s.l. (Leguminosae) of Indochina. J Jpn. Bot. 2021. 96. 5. 264-278
Obara Mami, Sato Sachiko, Takahashi Kumi, Kondo Yukiko, Hirose Masamichi, Nata Koji, Taira Eichi. Elucidation of expression and regulation mechanism of cell adhesion factor Gicerin/CD146 in cardiac hypertrophy model. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2020. 93. 1-P-067
Molecular cloning, expression and chromosomal localization of novel human REG family gene, REG III.
(American Diabetes Association 65th Scientific Sessions 2005)
Works (1)：
Reg因子による諸組織の再生促進機構の研究
1995 - 1997
Education (2)：
1985 - 1988 Tohoku University Graduate School of Medicine
1978 - 1984 Toyama Medical and Pharmaceutical University School of Medicine
Professional career (1)：
M.D. & Ph.D (Tohoku University)
Work history (3)：
2007/04 - 現在 Iwate Medical School School of Pharamacy Professor
1990/04 - 2007/03 Tohoku University Research associate
1988/04 - 1990/03 Japan Society for the Promotion of Science Research fellowship for young scientists
Committee career (2)：
2015/06 - 現在 日本臨床化学会 評議員
2008/04 - 現在 日本生化学会 評議員
Awards (1)：
1996/10 - ベーリンガーインゲルハイム ベルツ賞 新しいインスリン分泌機構とその病態
Association Membership(s) (6)：
THE JAPANESE SOCIETY OF CARBOHYDRATE RESEARCH
, The Asian Association for the Study of Diabetes
, JAPAN SOCIETY OF CLINICAL CHEMISTRY
, THE PHARMACEUTICAL SOCIETY OF JAPAN
, JAPAN DIABETES SOCIETY
, THE JAPANESE BIOCHEMICAL SOCIETY
