Rchr
J-GLOBAL ID：200901068690837686
Update date: Feb. 13, 2024
Yakura Hidetaka
YAKURA HIDETAKA | Yakura Hidetaka
Affiliation and department：
Job title：
Director
Homepage URL (2)：
http://science-he.blogspot.com/
,
https://hyakura.blogspot.com/
Research field (2)：
Immunology
, Philosophy and ethics
Research keywords (6)：
life
, nature
, Tyrosine phosphatases
, Signal transduction
, Immunology
, Philodophy of science, biology and medicine
Research theme for competitive and other funds (23)：
- 2004 - 2005 Regulation of mast Cell activation by tyrosine phosphatase
- 2002 - 2003 Novel mechanisms of Src-family kinase regulation by CD45
- 2001 - 2002 Dynamic regulation of Src-family tyrosine kinases by CD45
- 2000 - 2001 Search for CD45 ligand
- 1999 - 2000 Regulation of the immune system by tyrosine phosphatases and adaptor molecules
- 1999 - 2000 B cell signaling molecules which regulated by protein tyrosine phosphatase CD45
- 1999 - 2000 Signaling pathways regulated by PEST-domain tyrosine phosphatase PEP
- 1997 - 1998 Regulation of B cell antigen receptor-mediated signaling by SHP-1
- 1996 - 1998 Physiological significance of protein phosphatases on cellular signal transduction
- 1997 - 1997 Role of tyrosine phosphatases in lymphocyte signaling
- 1996 - 1997 CD45により制御されるB細胞核内因子の解析
- 1996 - 1997 Molecular mechanisms of PEST-domein tyrosine phosphatase PEP in B cells
- 1996 - 1996 B細胞シグナル伝達機構のチロシンホスファターゼによる制御
- 1995 - 1996 Molecular Mechanism of CD45 in B cell signal transduction
- 1995 - 1995 チロシンホスファターゼによるB細胞活性他・不活性の制御機構
- 1994 - 1995 ldentification of CD 45 ligand
- 1994 - 1994 チロシンホスファターゼによるB細胞活性化・不活化の制御機構
- 1993 - 1993 B細胞免疫寛容誘導におけるチロシンホスファターゼの役割
- 1992 - 1993 Receptor-type Protein Tyroshine Phosphatases Expressed in the Immune System and the Central Nervous System
- 1992 - 1992 レセプター型チロシンフォスファターゼのリンパ球活性化・腫瘍化における役割
- 1989 - 1990 Regulatory Mechanisms of Antibody Class Expression and Therapy of Autoimmunity
- 1987 - 1988 Mechanisms of B Cell Activation Mediated by B Cell Stimulatory Factor-1 and Lyb-2
- 1985 - 1986 Development of methods detecting HLA-D region genes and their products regulating disease susceptibility
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Papers (26)：
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Yakura H. Immunity in light of Spinoza and Canguilhem. Philosophies. 2020. 5. 38
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Yakura H. Cognitive and memory functions in plant immunity. Vaccines. 2020. 8. 541
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Yakura H. Response to Fred Keijzer’s comments. Adaptive Behavior. 2019. 27. 3. 179-180
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A hypothesis: CRISPR-Cas as a minimal cognitive system. Adaptive Behavior. 2019. 27. 3. 167-173
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Yakura H. Philosophize immunity. Bulletin of the Franco-Japanese Biological Society. 2019. 59. 3-12
ｍore...
MISC (14)：
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Yakura H, Shimaoka K. Study abroad as liberal arts. 2013. 245. 12. 1043-1053
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Akimoto M, Mishra K, Lim KT, Tani N, Hisanaga S, Katagiri T, Elson A, Mizuno K, Yakura H. Protein Tyrosine Phosphatase epsilon is a Negative Regulator of Fc epsilon RI-mediated Mast Cell Responses. SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2009. 69. 5. 401-411
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Nakata K, Yoshimaru T, Suzuki Y, Inoue T, Ra C, Yakura H, Mizuno K. Positive and negative regulation of high affinity IgE receptor signaling by Src homology region 2 domain-containing phosphatase 1. 2008. 181. 8. 5414-5424
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Ogimoto M, Ichinowatari G, Watanabe N, Tada N, Mizuno K, Yakura H. Impairment of B cell receptor-mediated Ca2+ influx, activation of mitogen-activated protein kinases and growth inhibition in CD72-deficient BAL-17 cells. International Immunology. 2004. 16. 7. 971-982
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Shrivastava P, Katagiri T, Ogimoto M, Mizuno K, Yakura H. Dynamic regulation of Src-family kinases by CD45 in B cells. Blood. 2004. 103. 4. 1425-1432
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Books (7)：
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Immunity: From Science to Philosophy
CRC Press 2024 ISBN:9781032776590
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From Immunity to Science as Philosophy
Misuzu Shobo 2023 ISBN:9784622096009
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Meditative Life of an Immunologist in Paris: In Search of a New Ethics of Knowledge
Ishiyaku Publishers 2022 ISBN:9784263206881
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A New Microbiology: From Microbiota to CRISPR
Misuzu Shobo 2019 ISBN:9784622087670
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The Game of Chance and Complexity: The New Science of Immunology
Misuzu Shobo 2018 ISBN:9784622086932
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Lectures and oral presentations (23)：
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Considering the relationship between science/medicine and philosophy
(Hokkaido Pediatric Advanced Medical Research Society 2020)
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Philosophize immunity
(The 190th French-Japanese Biological Society Meeting 2019)
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Think about recognition from the immunological perspective
(Meeting for the public lecture “The Ontology of Lukács” 2019)
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Immunity and cognition
(Colloque, Centre Cavaillès, Ecole Normale Supérieure 2019)
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Towards a metaphysics of immunity
(Tokyo University of Science, Research Institute for Biomedical Sciences Seminar 2017)
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Education (4)：
- 2009 - 2016 Paris Cité University Scientifi Knowledge
- 2007 - 2009 Paris 1 Panthéon-Sorbonne University Social and Humain Sciences
- 1973 - 1978 Graduate School of Medicine, Hokkaido University
- 1966 - 1972 Hokkaido University School of Medicine
Professional career (2)：
- MD, PhD (Graduate School of Medicine, Hokkaido University)
- Doctor of Philosophy (Epistemology of Science, History of Science and Technology) (Sorbonne University Paris Cité (currently, Paris Cité University))
Work history (7)：
Association Membership(s) (2)：
Japanese Association for Protein Tyrosine Phosphatase Research
, Japanese Society for Immunology
