Mukai Takao

ムカイタカオ | Mukai Takao

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://www.vmas.kitasato-u.ac.jp/faculty/as/as_study02.html

Research field (2)： Animal production science , Applied microbiology

Research keywords (5)：応用微生物学 , 微生物工学 , 動物微生物学 , Applied Microbiology , ANIMAL ENVIRONMENTAL SCIENCE

Research theme for competitive and other funds (25)：

2022 - 2025 ビフィズス菌の腸内定着の確立におけるミルクオリゴ糖やムチン糖鎖代謝産物の役割
2019 - 2022 Effects of sulfomucin-binding bifidobacteria on intestinal barrier function and analysis of gut colonization mechanisms
2015 - 2018 Studies on prevention of obesity-induced low-grade inflammation through improving the profile of gut microbiota by potential probiotic which binds to sulfated sugar chains
2015 - 2017 Characterization of bifidobacterial glycosidase: a new colonization factor that promotes bacterial adhesion to the intestinal mucin
2012 - 2015 Evaluation for the prevention of infection by lactic acid bacteria possessing the adhesion ability to mucin

2009 - 2011 Characterization of inhibitory factors of lactic acid bacteria against gastrointestinal pathogens

2010 - 乳酸菌の機能開発

2007 - 2008 Studies on novel prevention mechanisms of infection by adhesive lactic acid bacteria to mucosal surface of intestine

2005 - 2006 Studies on induction of anti-viral substances by lactic acid bacteria adhering to mucosal surface of intestine.

2003 - 2004 物質循環型牧場における肉牛飼育管理法確立のためのウイルスの分子疫学

2003 - 2004 Induction of mucin gene expression by lactic acid bacteria adhering to intestinal epithelial cells

2003 - プレバイオティクスに関する研究

2001 - 2002 Molecular analysis of adhesion protein produced by lactic acid bacteria including Bifidobacterium for probiotic application

2002 - 腸内細菌の環境応答機構の解析

2002 - Inhibition of coronavirus by bzomolecules

1999 - 2000 感染予防へ向けたレクチン産生性ビフィズス菌の細胞接着機構の解明

1992 - 2000 Pharmacokinetics of sulfa drugs in chicken

1997 - 1998 レクチンを有する乳酸菌の細胞接着性と消化管系病原微生物に対する感染予防効果

1997 - 1998 感染防御を目的としたビフィズス菌の腸上皮細胞への接着機構の解明

1996 - 1996 感染防御を目的とした腸内有用乳酸菌の上皮細胞の接着機構の解明

1995 - 1995 畜産排水処理に関わる微生物のフロック発現因子の解析

1994 - 1994 畜産排水処理に関わる微生物由来新規タンパク質の機能特性とその遺伝学的解析

1993 - 1993 畜産廃水処理に関わる微生物が生産する新規タンパク質の機能特性とその遺伝学的解析

腸内乳酸菌と宿主との相互作用

ADHESION MECHANISM OF LACTOBACILLI TO EPITHELIAL SURFACE OF INTESTINE

Show all

Papers (30)：

Keita Nishiyama, Takao Mukai. Adhesion Inhibition Assay for Helicobacter pylori to Mucin by Lactobacillus. Methods in molecular biology (Clifton, N.J.). 2024. 2763. 353-358
Keita Nishiyama, Cheng-Chung Yong, Nobuko Moritoki, Haruki Kitazawa, Toshitaka Odamaki, Jin-Zhong Xiao, Takao Mukai. Sharing of Moonlighting Proteins Mediates the Symbiotic Relationship among Intestinal Commensals. Applied and environmental microbiology. 2023. e0219022
Tatsunari Yokoi, Keita Nishiyama, Yuka Kushida, Kazuya Uribayashi, Takahiro Kunihara, Rika Fujimoto, Yuji Yamamoto, Masahiro Ito, Tsuyoshi Miki, Takeshi Haneda, et al. O-acetylesterase activity of Bifidobacterium bifidum sialidase facilities the liberation of sialic acid and encourages the proliferation of sialic acid scavenging Bifidobacterium breve. Environmental microbiology reports. 2022. 14. 4. 637-645
Keita Nishiyama, Tatsunari Yokoi, Makoto Sugiyama, Ro Osawa, Takao Mukai, Nobuhiko Okada. Roles of the Cell Surface Architecture of Bacteroides and Bifidobacterium in the Gut Colonization. Frontiers in Microbiology. 2021. 12
Saki MATSUI, Hazuki AKAZAWA, Yuji TSUJIKAWA, Itsuko FUKUDA, Yoshihiro SUZUKI, Yuji YAMAMOTO, Takao MUKAI, Yasuhito SHIRAI, Ro OSAWA. Milk oligosaccharide-mediated cross-feeding between Enterococcus gallinarum and lactobacilli in the gut microbiota of infant rats. Bioscience of Microbiota, Food and Health. 2021. 40. 4. 204-211

ｍore...

MISC (28)：

西山啓太, 向井孝夫. Colonization strategies of bifidobacteria, viewed from symbiotic relationships of gut bacteria. アグリバイオ. 2023. 6. 14
齋藤史, 磯奏子, 尾淵駿, 吹谷智, 横田篤, 山本裕司, 向井孝夫. Bifidobacterium animalis subsp.lactisが有するストレス耐性遺伝子の探索. 日本乳酸菌学会誌. 2019. 30. 2
齋藤史, 磯奏子, 小泉亮子, 原翔, 吹谷智, 横田篤, 山本裕司, 向井孝夫. ビフィズス菌における低温生残性向上機構の解析. 日本乳酸菌学会誌. 2018. 29. 2
西山啓太, 長井暁, 吹谷智, 横田篤, 山本裕司, 向井孝夫, 岡田信彦. Bifidobacterium bifidumの細胞外シアリダーゼの腸粘液との相互作用と糖の資化における役割. 腸内細菌学雑誌. 2018. 32. 2
西山啓太, 向井孝夫. Factors involved in the interaction between Bifidobacterium and the host mucosal surface. 日本乳酸菌学会誌. 2018. 29. 1

ｍore...

Books (7)：

ｍore...

Education (2)：

Professional career (1)：

Work history (6)：

Show all

Association Membership(s) (7)：

アメリカ微生物学会 , 日本乳酸菌学会 , 日本細菌学会 , 応用微生物学会 , 日本食品衛生学会 , 日本農芸化学会 , 日本畜産学会

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page