Rchr
J-GLOBAL ID：200901069238685255
Update date: Jan. 31, 2024
Yamamoto Hideki
ヤマモト ヒデキ | Yamamoto Hideki
Affiliation and department：
Job title：
Associate Professor
Research field (3)：
Pathobiochemistry
, Medical biochemistry
, Cell biology
Research theme for competitive and other funds (10)：
- 2020 - 2023 Regulation of signal response through a novel DKK1 receptor "CKAP4"
- 2014 - 2017 Regulation of membrane traffic of Wnt and its receptors
- 2011 - 2013 Selective activation of Wnt signaling pathway using with purified Wnt proteins
- 2010 - 2011 細胞分裂期におけるWntシグナル因子Dvlによる紡錘体形成の制御機構
- 2009 - 2011 Regulation of signaling network and cellular responses by Wnt
- 2009 - 2010 Regulation of Wnt signaling by different endocytic pathway
- 2005 - 2009 Abnormal Differentiation in Cancer Cells and Intracellular Signaling
- 2005 - 2006 エンドサイトーシスによるWntシグナル伝達経路の制御機構の解析
- 2003 - 2004 Regulation of the Wnt signal by receptor-mediated endocytosis
- 2000 - 2004 Identification of intercellular signal transduction molecules and analysis of their functional abnormality in human cancer
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Papers (50)：
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Hirokazu Kimura, Ryota Sada, Naoki Takada, Akikazu Harada, Yuichiro Doki, Hidetoshi Eguchi, Hideki Yamamoto, Akira Kikuchi. The Dickkopf1 and FOXM1 positive feedback loop promotes tumor growth in pancreatic and esophageal cancers. Oncogene. 2021. 40. 26. 4486-4502
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山本 英樹, 佐田 遼太, 菊池 章. アネキシンA2によるDKK1受容体CKAP4の細胞膜への輸送制御. 日本生化学会大会プログラム・講演要旨集. 2020. 93回. [P-318]
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Ryota Sada, Hirokazu Kimura, Yuko Fukata, Masaki Fukata, Hideki Yamamoto, Akira Kikuchi. Dynamic palmitoylation controls the microdomain localization of the DKK1 receptors CKAP4 and LRP6. Science signaling. 2019. 12. 608
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Hideki Yamamoto, Akira Sato, Akira Kikuchi. Apical secretion of Wnt1 in polarized epithelial cells is regulated by exocyst-mediated trafficking. Journal of biochemistry. 2017. 162. 5. 317-326
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Hideki Yamamoto, Daisuke Umeda, Shinji Matsumoto, Akira Kikuchi. LDL switches the LRP6 internalization route from flotillin dependent to clathrin dependent in hepatic cells. JOURNAL OF CELL SCIENCE. 2017. 130. 20. 3542-3556
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Education (1)：
- - 2001 Hiroshima University Graduate School, Division of Medical Sciences
Work history (3)：
- 2011/04/01 - 現在 Osaka University Graduate School of Medicine Division of Medicine Associate Professor
- 2009/12/01 - 2011/03/31 Osaka University Division of Physiological Sciences Associate Professor
- 2007/12 - 2009/11 広島大学・准教授
Awards (1)：
- 2007/10 - Japanese Biochemistry Society Japanese Biochemistry Society Young Investigator Award
Association Membership(s) (3)：
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