Satoh Mamoru

サトウマモル | Satoh Mamoru

Affiliation and department：
Job title： Guraduate student,Special researcher of the Japan Society for the Promotion of Science (DC2)

Research field (1)： Other

Research keywords (27)： Clinical Chemistry , S-Plus , R , 多変量解析 , 質量分析計 , 二次元電気泳動 , プロテオーム解析 , タンパク質 , 膵臓 , 糖尿病 , 甲状腺機能低下 , 疾患関連タンパク質 , マウス , ラット , S-Plus , R , Multivariate analysis , Mass Spectrometry , Two-dimensional gel electrophoresis , Proteome analysis , Protein , pancreas , Diabetes , Hypothyroidism , Disease related protein , mouse , rat

Research theme for competitive and other funds (30)：

2019 - 2022 分泌蛋白を含む癌微小環境と補体因子による膵胆道癌進展機構の解明と測定系の開発
2019 - 2022 脱髄型ギラン・バレー症候群の新規標的分子の探索と分子相同性による発症機序の解明
2018 - 2021 メタゲノムによる新意義を持つ臨床細菌検査の開発とそれへのDNAメチル化解析の応用
2018 - 2021 臨床検査応用を目指したLC-MS/MS定量測定法の開発と基盤技術の構築
2018 - 2021 ユビキトーム解析による歯周疾患のバイオマーカー開発

2017 - 2020 質量分析計によるトキソプラズマ症の再活性化検出法及び重症度の評価法の確立

2017 - 2020 MS臨床検査をハイスループット化するアナログ/アイソトポログ誘導体化法の開発

2017 - 2020 Exploration of molecular biomarker for early prognostification of spinal cord injury

2016 - 2019 Elucidation a novel development mechanism of T cell acute lymphoblastic leukemia by quantitative proteome analysys

2016 - 2019 Clinical application of rapid bacterial identification using mass spectrometry

2016 - 2019 Expression of annexin II and stromal tenascin C promotes epithelial to mesenchymal transition and correlates with distant metastasis in pancreatic cancer

2016 - 2018 The impact of visceral obesity-induced insulin resistance and chronic inflammation on breast cancer chemotherapy for Japanese patients

2015 - 2018 Development of the quantitative measurement methods by LC-MS/MS for clinical laboratory applications.

2015 - 2018 Development of immunocomplex pretreatment method for mass spectrometry (MS, Immuno-MS) which is applicable to clinical testing

2015 - 2018 Application of modificomic technologies to discover and identify biomarkers for periodontal diseases

2015 - 2017 Development of LC-MS/MS-based accurate quantification methods for assessing serum vitamin D metabolites

2015 - 2017 Search for chemotherapeutic sensitive markers of esophageal squamous cell carcinoma by proteomic analysis

2014 - 2017 Proteome analysis of toxoplasmic retinochoroiditis-a quest of biomarker

2014 - 2017 Clinical and bacteriological analysis of nontypeable Haemophilus influenzae isolated from invasive diseases

2013 - 2015 プロテオーム解析を用いた脱髄型ギラン・バレー症候群の新規標的分子の網羅的解析

2013 - 2015 Multidisciplinary modificomics to search for novel and early markers to detect hepatobiliary cancers

2012 - 2015 Identification of drug resistance-related proteins in pancreatic cancer by SILAC quantitative proteomic approach.

2012 - 2015 Clinical application of rapid bacterial identification using mass spectrometry

2011 - 2013 Clinical appliciation of cancer treatment by revealing alternative splicing mechanism of c-myc transcriptional suppressor FBP-interacting repressor

2010 - 2011 Development of a diagnostic marker and method for pancreatic cancer using secretome and proteome analysis.

2008 - 2009 A searching of novel biomarker in digestive organ cancer serum and the establishment of a practical diagnostic method using unique high-yield peptide-extraction method.

2006 - 2007 患者血清中の自己抗体を用いた消化器ガン診断法の開発

2002 - 2003 プロテオームによる糖尿病病態解析法の開発

疾病関連たんぱく質の探索と解析

A proteome analysis of sickness-related protein

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Papers (113)：

土田祥央, 村田正太, 宮部安規子, 中嶋優貴, 飯塚和秀, 佐藤守, 松下一之, 中山智祥, 野村文夫, 梅村啓史. マトリックス支援レーザー脱離イオン化飛行時間型質量分析法(Matrix-assisted laser desorption/ionization-time of flight mass spectrometry MALDI-TOF MS)による細菌同定における試料調製時の湿度の影響. JSBMS Letters. 2024. 49. Suppl. 118-118
梅村啓史, 滝脇正貴, 菊谷善國, 福沢世傑, 阿部健太郎, 藤野清孝, 中山智祥, 土田祥央, 佐藤守, 野村文夫, et al. 最新の質量分析技術と臨床検査医学のコラボレーション質量分析法によるメラニン中間代謝産物の血中濃度測定と悪性黒色腫への臨床応用. 日本臨床検査医学会誌. 2023. 71. 3. 144-144
Sachio Tsuchida, Koji Yamashita, Syota Murata, Akiko Miyabe, Mamoru Satoh, Kazuyuki Matsushita, Tomohiro Nakayama, Fumio Nomura, Hiroshi Umemura. Evaluation of a novel sample preparation method for identifying Aspergillus fumigatus using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry: Combining Yatalase and silica beads treatment. Journal of Microbiological Methods. 2023. 106706-106706
梅村啓史, 滝脇正貴, 菊谷善國, 福沢世傑, 阿部健太郎, 藤野清孝, 中山智祥, 土田祥央, 佐藤守, 野村文夫, et al. 最新の質量分析技術と臨床検査医学のコラボレーション質量分析法によるメラニン中間代謝産物の血中濃度測定と悪性黒色腫への臨床応用. 日本臨床検査医学会誌. 2022. 70. 補冊. 032-032
Masaki Takiwaki, Fumio Nomura, Mamoru Satoh, Sachio Tsuchida, Kazuo Otake, Junko Takagi. Development of a sensitive liquid chromatography-tandem mass spectrometry method for quantification of human plasma arginine vasopressin. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 2021. 1181

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MISC (164)：

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Works (3)：

膵分泌顆粒の解析
2001 -
Discrete Density Distribution and Size Heterogenity of Rat Pancreatic Zymogen Granules
2001 -
新生仔期DES投与により不可逆的増殖・角質化を示すマウスの膣における蛋白質発現
2000 -

Education (4)：

- 2001 Kitasato University
- 2001 Kitasato University Graduate school of Fundamental Life Science Biosciences
- 1999 Kitasato University School of Science Department of Physics
- 1999 Kitasato University Faculty of Science Physics

Professional career (1)：

Master (Kitasato University)

Work history (6)：

2015/04 - Chiba University Hospital
2008/04 - 2014/03 Chiba University Hospital
2005/04 - 2008/03 Chiba University School of Medicine
2002 - - Special researcher of the Japan Society
2001 - ~ 日本学術振興会特別研究員(DC2)

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Association Membership(s) (8)：

比較内分泌学会 , 生化学会 , The Japan Society for Comparative Endocrinology , The Japanese Biochemical Society , 日本医用マススペクトル学会 , 日本臨床化学会 , 日本医療検査科学会 , 日本プロテオーム学会

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