Shimazu Takeshi

2019 - 2022 Trauma-specific memory-like regulatory T-cell responses and fundamental research for clinical translation

2019 - 2022 Brain circulation based on a change of the rSO2 in patients with cardiopulmonary arrest in the pre-hospital settings.

2018 - 2022 Myeloid-derived suppressor cells infiltrate the brain and suppress neuroinflammation in a mouse model of focal traumatic brain injury

2018 - 2021 New approach of improvement of emergency medical system with population-based registry about emergency patients transported by ambulance

2017 - 2020 Quality improvement of telephone-assisted dispatch system in emergency medical services for out of hospital cardiac arrest patients

2016 - 2020 A novel approach for diagnosis of meningitis and encephalitis using metagenomic sequencing

2015 - 2020 Comprehensive Registry of Intensive Cares for OHCA Survival (CRITICAL) Study in Osaka, Japan

2016 - 2019 Explanatory research of consciousness related substances in iPS cell-derived brain microvascular endothelial cell models

2016 - 2019 Elucidation of mechanisms between endothelial injury and host immune response in severe trauma patients

2016 - 2019 Citrullinated histon H3 for control of ciritical illness

2016 - 2019 A novel development of regenerative therapy following acute systemic inflammatory response syndrome: the effects of transplantation of bone marrow-derived mononuclear cells and new rejuvenation factor

2015 - 2018 A novel strategy for organ dysfunctions following systemic inflammatory response syndrome: the effect of new rejuvenation factor GDF11

2015 - 2018 elucidation of the brain circulation during prehospital resuscitation

2015 - 2018 Establishment of methods for immune response analysis of lymphocytes and neutrophils against sepsis and trauma

2015 - 2018 Blast induced Traumatic Brain Injury and Cardiovascular Response

2014 - 2017 The analysis of the gut microbiota change in severe emergency patients via high-throughput DNA sequencing

2013 - 2017 New strategy for critically ill patients by control of NETs

2013 - 2016 At the attempted suicides of secondary prevention effect of strengthening medical social worker intervention

2013 - 2016 Regenerative therapy following severe insults: Establishment of cell transplantation and elucidation of immunologic response

2012 - 2015 A novel strategy for heat stroke: targeted therapy for free nucleotides

2012 - 2015 Study on Comprehensive Registry of In-Hospital Intensive Care on OHCA Survival

2012 - 2015 A study on correlation between the occurrence point and selection of prehospital strategy of treatment for severe and critical patients using Geographic Information System (GIS)

2012 - 2015 Elucidation of the brain circulation during resuscitation.

2010 - 2014 The development of cell transplantation therapy against sepsis-associated multiple organ dysfunction targeted at endogenous stem cell function.

2009 - 2011 The effects of"Preemptive Infection Control" in critical care center

2007 - 2009 Regenerative response to insults : a novel strategy based on endothelial regeneration

2006 - 2008 A Study on the Systematic Approach to Emergency Management Medicine : From Inpatient Collapse to Local Cooperation tor Disaster and Terrorism

2005 - 2007 Gut flora and synbiotics therapy in patients with severe SIRS

2004 - 2006 ラット肺微少循環機能のリアルタイム計測技術の開発と応用

2003 - 2005 Immune response to severe insults: reaction through Toll-like receptors

2002 - 2004 Stress responses and leukocyte functions in sepsis

2001 - 2003 神経幹細胞移植による頭部外傷後の神経機能回復

2001 - 2003 脳死後の肺障害発生機序の解明と肺機能温存法開発に関する研究

2001 - 2003 Telemedical support of emergency medicine using real-time telecommunication system.

2000 - 2002 生体顕微鏡を用いた肺微小循環の可視化解析に関する研究

1999 - 2001 Investigation of the mechanism in multiple organ failure and the new approach by regulating leukocyte function

1998 - 2000 Elucidation of the mechanisms of cross-talk between the neurological, endocrine, and immune systems in the biological response to physical insults

1994 - 1996 Role of nitric oxide in septic shock

軟部組織の重症感染症の病態に関する研究

重症患者における免疫能の変化に関する研究

重症患者における呼吸循環動態に関する研究

Study on pathop hysiology and predisposition of necrotizing soft tissue infections

Study on Alterations in Immunologic Function in the Critically Ill

Study on Cardiopulmonary Function in the Critically Ill