Hashii Yoshiko

Affiliation and department：
Homepage URL (1)： http://www.med.osaka-u.ac.jp/pub/ped/www/Welcome-jp.html

Research field (2)： Tumor diagnostics and therapeutics , Fetal medicine/Pediatrics

Research keywords (7)： Cancer Immunotherapy , 移植 , 免疫 , 血液 , transplantation , Immunology , hematology

Research theme for competitive and other funds (12)：

2022 - 2026 Identification of novel therapeutic target molecules based on correlation between leukemia stem cell heterogeneity and in vivo dynamics
2021 - 2024 腸管細胞の獲得免疫における動態評価
2017 - 2020 Clarification of the mechanism of effectiveness of the oral cancer vaccine a platform expressing a cancer antigen
2014 - 2017 Development new immunotherapy for pediatric cancer using human iPSCs
2013 - 2017 Elucidation and control of molecular mechanism in WT1 peptide vaccine therapy after allogeneic hematopoietic stem cell transplantation

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Papers (180)：

Hisashi Ishida, Toshihiko Imamura, Ryoji Kobayashi, Yoshiko Hashii, Takao Deguchi, Takako Miyamura, Megumi Oda, Masaki Yamamoto, Keiko Okada, Hideki Sano, et al. Differential impact of asparaginase discontinuation on outcomes of children with T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma. Cancer Medicine. 2024. 13. 12
Daisuke Tomizawa, Jun Matsubayashi, Shotaro Iwamoto, Hidefumi Hiramatsu, Daisuke Hasegawa, Hiroshi Moritake, Daiichiro Hasegawa, Kiminori Terui, Asahito Hama, Shin-Ichi Tsujimoto, et al. High-dose cytarabine induction therapy and flow cytometric measurable residual disease monitoring for children with acute myeloid leukemia. Leukemia. 2024. 38. 1. 202-206
Hisashi Ishida, Yuki Arakawa, Daiichiro Hasegawa, Ikuya Usami, Yoshiko Hashii, Yasuyuki Arai, Satoshi Nishiwaki, Dai Keino, Keisuke Kato, Maho Sato, et al. Reduced-intensity allogenic transplantation for children and adolescents with Philadelphia chromosome-positive acute lymphoblastic leukemia. Annals of hematology. 2023
Hisashi Ishida, Shin-Ichi Tsujimoto, Daisuke Hasegawa, Hirotoshi Sakaguchi, Shohei Yamamoto, Masakatsu Yanagimachi, Katsuyoshi Koh, Akihiro Watanabe, Asahito Hama, Yuko Cho, et al. Optimizing transplantation procedures through identification of prognostic factors in second remission for children with acute myeloid leukemia with no prior history of transplant. Haematologica. 2023
Mio Yano, Hisashi Ishida, Junichi Hara, Hiroshi Kawaguchi, Etsuro Ito, Akiko Moriya-Saito, Yoshiko Hashii, Takao Deguchi, Takako Miyamura, Atsushi Sato, et al. Outcome of hematopoietic stem cell transplantation in pediatric patients with acute lymphoblastic leukemia not in remission enrolled in JACLS ALL-02. International journal of hematology. 2023. 118. 3. 364-373

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MISC (321)：

Atsushi Sato, Hirohide Kawasaki, Takao Deguchi, Yoshiko Hashii, Yuka Iijima-Yamashita, Sachiko Yonezawa, Chiyo K. Imamura, Haruko Shima, Hirotoshi Sakaguchi, Yuichi Kodama, et al. Chemotherapy with the Use of TKIs Based on MRD Has the Potential to Avoid Hematopoietic Stem Cell Transplantation in Treatment for Children with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph plus ALL). Results of the Japanese Pediatric Leukemia/Lymphoma Study Group (JPLSG) Study ALL-Ph13. BLOOD. 2021. 138
橋井佳子, 岡芳弘, 坂田尚己, 渡辺新, 尾路祐介, 保仙直毅, 山本紘司, 服部聡, 中島博子, 中田潤, et al. WT1-targeteing immunotherapy after allogeneic HSCT in children with refractory acute leukemias(和訳中). 日本血液学会学術集会. 2021. 83回. OS1-5
Naoki Kagawa, Takako Miyamura, Ryuichi Hirayama, Chisato Yokota, Tomoyoshi Nakagawa, Noriyuki Kijima, Manabu Kinoshita, Yoshiko Hashii, Keiko Okada, Jyunichi Hara, et al. ASSESSMENT OF NEUROCOGNITIVE FUNCTION AND MRI PARAMETERS IN LONG-TERM SURVIVORS WITH POSTERIOR FOSSA TUMORS: A COMPARISON BETWEEN MEDULLOBLASTOMAS TREATED BY REDUCED-DOSE CRANIOSPINAL IRRADIATION AND OTHER TUMORS. NEURO-ONCOLOGY. 2020. 22. 439-439
宮村能子, 橋井佳子, 藤原隆弘, 中川夏季, 五百井彩, 桂聡哉, 皆川光, 横井健人, 吉田寿雄, 大薗恵一. 小児・AYA世代血液・悪性腫瘍疾患治療後のQOL評価. 日本小児血液・がん学会雑誌. 2019. 56. 4. 342-342
香川尚己, 平山龍一, 橋井佳子, 三善陽子, 木下学, 有田英之, 原純一, 貴島晴彦. 中枢神経系胚細胞腫瘍および視神経視床下部神経膠腫の病態と治療. 日本内分泌学会雑誌. 2019. 95. Suppl.HPT. 27-32

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Books (3)：

小児血液・腫瘍学 = Pediatric hematology and oncology
診断と治療社 2015 ISBN:9784787820983
これでOK!小児救急ケーススタディ : Osaka University, Kansai Medical University
診断と治療社 2015 ISBN:9784787821270
Acute Leukemia
Mariastefania Antica 2011

Lectures and oral presentations (24)：

HEMATOPOIETIC STEM CELL TRANSPLANTATION FOR SEVERE COMBINED IMMUNODEFICIENCY IN JAPAN: A NATIONWIDE RETROSPECTIVE ANALYSIS
(46th Annual Meeting of the European Society for Blood and Marrow Transplantation 2020)
IMPACT OF HLA-MISMATCH ON OUTCOMES AFTER UNRELATED BONE MARROW TRANSPLANTATION IN PEDIATRIC PATIENTS: A RETROSPECTIVE ANALYSIS BY THE JSHCT HLA WORKING GROUP
(46th Annual Meeting of the European Society for Blood and Marrow Transplantation 2020)
WT1蛋白を標的としたがんワクチン治療の現状とあらたな展開
(第123回日本小児科学会学術集会 2020)
MECOM(EVI1)遺伝子変異による無巨核球性血小板減少症を伴う橈骨尺骨融合症
(日本小児血液・がん学会雑誌 2018)
Stem Cell Transplantation for Patients with Adrenoleukodystrophy in Japan
(BONE MARROW TRANSPLANTATION 2018)

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Works (1)：

HGFの血液系への働き
1994 -

Professional career (1)：

医学 (大阪大学)

Work history (4)：

2018/04 - 2018/12 大阪大学医学部附属病院病院教授
2013/07 - 2016/06 医局長
2011/07 - 2013/06 病棟医長
2009/10 - 2011/06 外来医長

Committee career (5)：

2020/05 - 現在日本造血細胞移植学会 WGタスクフォース
2018/07 - 現在日本小児血液・がん学会学会誌編集委員会
2014/04 - 2020/06 日本小児血液がん学会造血細胞移植委員会委員長
2014/04 - 日本造血細胞移植学会一元管理委員会
日本造血細胞移植学会造血幹細胞移植患者手帳作成委員会

Awards (4)：

2018 - 日本白血病基金一般研究賞免疫制御・エピゲノムに関与する多因子のクラスタリングによる小児白血病の包括的評価を行う。臨床情報と比較することで小児に適切な免疫制御因子の使用やエピゲノム治療薬の開発の可能性を探索する。
2010/10 - 日本白血病基金一般研究賞小児白血病に対する同種造血幹細胞移植後のWT1ペプチドワクチン療法の開発と抗腫瘍免疫動態の解析
2006/10 - 日本白血病基金一般研究賞フローサイトメトリーによる小児骨髄異形成症候群に対する細胞表面マーカーの検索
2005/11 - 日本小児血液がん学会研究奨励賞

Association Membership(s) (7)：

The American Society of Clinical Oncology , American Society of Hematology , 日本癌学会 , 日本小児血液がん学会 , 日本造血細胞移植学会 , 臨床血液学会 , 日本血液学会

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