Rchr
J-GLOBAL ID：200901070912821354   Update date: Nov. 03, 2024

Tadagaki Kenjiro

タダガキ ケンジロウ | Tadagaki Kenjiro
Affiliation and department：
Kyoto Prefectural University of Medicine Graduate School of Medical Science

About Kyoto Prefectural University of Medicine Graduate School of Medical Science


Research field  (4)： Molecular biology ,  Pathobiochemistry ,  Tumor biology ,  Hematology and oncology
Research keywords  (5)： がん代謝 ,  遺伝子発現 ,  細胞分化 ,  ゲノム編集 ,  転写因子
Research theme for competitive and other funds  (5)：
  • 2024 - 2027 造血関連転写因子RUNX1遺伝子の発現制御機構の解明と新規治療法開発への応用
  • 2022 - 2023 白血病関連転写因子RUNX1の発現機構の解析と造血系予防医学への応用
  • 2019 - 2022 Elucidation of cell differentiation by hematopoietic transcription factor RUNX1 and translation to a novel molecular target strategy
  • 2016 - 2019 Regulation mechanisms of hematopoietic transcription factor RUNX1 through the transcription network analyses
  • 2013 - 2015 mTOR signaling mechanisms dependent on amino acid transporter
Papers (21)：
  • Renshi Kawakatsu, Kenjiro Tadagaki, Kenta Yamasaki, Yasumichi Kuwahara, Shinichiro Nakada, Tatsushi Yoshida. The combination of venetoclax and quercetin exerts a cytotoxic effect on acute myeloid leukemia. Scientific Reports. 2024. 14. 1
  • Tatsushi Yoshida, Kenta Yamasaki, Mano Horinaka, Kenjiro Tadagaki. Coffee extracts and caffeine upregulate the expression of the immune checkpoint factors, PD-1 and PD-L1. International Journal of Functional Nutrition. 2024. 5. 1
  • Renshi Kawakatsu, Kenjiro Tadagaki, Kenta Yamasaki, Tatsushi Yoshida. Venetoclax efficacy on acute myeloid leukemia is enhanced by the combination with butyrate. Scientific Reports. 2024. 14. 1
  • Tatsushi Yoshida, Kenta Yamasaki, Kenjiro Tadagaki. Caspase inhibition improves viability and efficiency of liposomal transfection. Scientific Reports. 2023. 13. 1
  • Akifumi Matsumoto, Tatsushi Yoshida, Takahiro Shima, Kenta Yamasaki, Kenjiro Tadagaki, Noriko Kondo, Yasumichi Kuwahara, Dong-Er Zhang, Tsukasa Okuda. C11orf21, a novel RUNX1 target gene, is down-regulated by RUNX1-ETO. BBA Advances. 2022. 2. 100047-100047
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MISC (6)：
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Lectures and oral presentations  (17)：
  • プロテオミクス的手法によるRUNX1/AML1遺伝子発現を制御する新規転写因子の探索
    (日本生化学会大会 2023)
  • RUNX1/AML1遺伝子の発現を制御する新規候補転写因子
    (日本癌学会学術総会 2023)
  • G1サイクリン遺伝子CCND1はRUNX1とその白血病関連融合型蛋白RUNX1-ETOの転写標的となる
    (日本分子生物学会 2022)
  • RUNX1/AML1遺伝子の発現を制御する新規転写因子群の探索
    (日本生化学会大会 2022)
  • A seaweed-derived compound that inhibits growth of acute myeloid leukemia cells.
    (2021)
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Education (3)：
  • 2001 - 2005 Osaka University Graduate School of Medicine
  • 1999 - 2001 Osaka University Graduate School of Engineering Division of Biotechnology
  • 1995 - 1999 Osaka University School of Engineering Division of Applied Science
Professional career (1)：
  • 博士(医学) (大阪大学)
Work history (6)：
  • 2023/04 - 現在 Kyoto Prefectural University of Medicine Graduate School of Medical Science
  • 2014/07 - 2023/03 Kyoto Prefectural University of Medicine Graduate School of Medical Science
  • 2012/07 - 2014/06 Osaka University Graduate School of Medicine
  • 2008/04 - 2012/06 フランス パリ第五大学 Institut Cochin 博士研究員
  • 2005/04 - 2008/03 Osaka University Graduate School of Medicine
Show all
Awards (1)：
  • 2008 - フランス パリ第五大学 フェローシップ
Association Membership(s) (5)：
THE JAPANESE SOCIETY OF HEMATOLOGY ,  THE JAPANESE CANCER ASSOCIATION ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE SOCIETY FOR VIROLOGY
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