Rchr
J-GLOBAL ID：200901071320433161
Update date: Feb. 01, 2024
TSUJITA Tadayuk
ツジタ タダユキ | TSUJITA Tadayuk
Affiliation and department：
Job title：
Associate Professor
Homepage URL (1)：
http://seika.ag.saga-u.ac.jp/
Research field (1)：
Applied biochemistry
Research theme for competitive and other funds (8)：
- 2022 - 2026 Molecular mechanisms of the alternative splicing regulation in response to a variable nutrient environment in plants
- 2022 - 2025 New strategic approach for ameliorate hypoxic injury using the PHD1 specific inhibitor and definition of the molecular mechanism.
- 2022 - 2025 Controlling the anti aging mechanism through modification of the protein translation pathway and Amine metabolizing pathway
- 2021 - 2025 Effects of ALDH2 Polymorphism and Alcohol Consumption on Melanoma Onset-Experimental Approach
- 2019 - 2022 Controlling the aging and metabolic process with anti-stress enzyme expression profiles through those controlling transcriptional factor, Nrf1
- 2017 - 2020 Development the culture method for primary hepatocyte to keeping a same response range in vitro and in vivo for exogenous stimulus.
- 2016 - 2019 Modulation and/or controlling of the aging event by the basic anti-oxidative response with environmental transcriptional factor Nrf1
- 2013 - 2015 Does adjusting Nrf1 active status lead to remediate reductive stress and aging-related diseases?
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Papers (40)：
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Atsushi Hatanaka, Sota Nakada, Gen Matsumoto, Katsuya Satoh, Iori Aketa, Akira Watanabe, Tomoaki Hirakawa, Tadayuki Tsujita, Tsuyoshi Waku, Akira Kobayashi. The transcription factor NRF1 (NFE2L1) activates aggrephagy by inducing p62 and GABARAPL1 after proteasome inhibition to maintain proteostasis. Scientific reports. 2023. 13. 1. 14405-14405
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Sudarma Bogahawaththa, Tomoaki Kawamura, Udari Bandaranayake, Tomoaki Hirakawa, Goki Yamada, Hana Ishino, Tsuzumi Hirohashi, Shin-Ichi Kawaguchi, Kavindra K Wijesundera, Missaka P B Wijayagunawardane, et al. Identification and mechanistic investigation of ellagitannins from Osbeckia octandra that attenuate liver fibrosis via the TGF-β/SMAD signaling pathway. Bioscience, biotechnology, and biochemistry. 2023. 87. 11. 1295-1309
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Kento Sonoda, Sudarma Bogahawaththa, Akito Katayama, Saki Ujike, Sae Kuroki, Naho Kitagawa, Kohichi Hirotsuru, Norio Suzuki, Toshio Miyata, Shin-Ichi Kawaguchi, et al. Correction to "Prolyl Hydroxylase Domain Protein Inhibitor Not Harboring a 2-Oxoglutarate Scaffold Protects against Hypoxic Stress". ACS pharmacology & translational science. 2022. 5. 7. 512-512
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Kento Sonoda, Sudarma Bogahawatta, Akito Katayama, Saki Ujike, Sae Kuroki, Naho Kitagawa, Kohichi Hirotsuru, Norio Suzuki, Toshio Miyata, Shin-Ichi Kawaguchi, et al. Prolyl Hydroxylase Domain Protein Inhibitor Not Harboring a 2-Oxoglutarate Scaffold Protects against Hypoxic Stress. ACS pharmacology & translational science. 2022. 5. 5. 362-372
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Sudarma Bogahawaththa, Suranga P Kodithuwakku, Kavindra K Wijesundera, Eranga H Siriweera, Lalith Jayasinghe, Waruna L Dissanayaka, Jayanthe Rajapakse, Chandana B Herath, Tadayuki Tsujita, Missaka P B Wijayagunawardane. Anti-Fibrotic and Anti-Angiogenic Activities of Osbeckia octandra Leaf Extracts in Thioacetamide-Induced Experimental Liver Cirrhosis. Molecules (Basel, Switzerland). 2021. 26. 16
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MISC (2)：
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青木淳賢, 可野邦行, 濱直人, 辻田忠志, 土井隆行, 菅原明, 清水律子, 大島吉輝, 山本雅之. アカデミック創薬-東北からの発信-. 日本薬学会年会要旨集(CD-ROM). 2015. 135th. 1. ROMBUNNO.S20-3-155
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Rowena Hancock, Helene Bertrand, Shama Naz, Tadayuki Tsujita, John Hayes, Geoff Wells. Design, synthesis and biological evaluation of peptide inhibitors of the Keap1-Nrf2 protein-protein interaction. CANCER RESEARCH. 2011. 71
Education (3)：
- 2002 - 2005 Nara Institute of Science and Technology Graduate School of Biological Sciences
- 2000 - 2002 九州大学大学院 生物資源環境科学府 生物機能科学専攻
- 1996 - 2000 Kyushu University School of Agriculture
Work history (8)：
- 2023/04 - 現在 Kagoshima University Associate Professor
- 2023/04 - 現在 Saga University Associate Professor
- 2015/08 - 2023/04 Saga University Faculty of Agriculture, Laboratory of Biochemistry Lecturer
- 2022/10 - 2023/03 Kagoshima University United Graduate School of Agricultural Sciences Lecturer
- 2017/04 - 2022/09 Kagoshima University United Graduate School of Agricultural Sciences, Course of Biological Science and Technology
- 2011 - 2015 Tohoku University Graduate School of Medicine, Department of Medical Biochemistry Assistant Professor
- 2008 - 2011 University of Dundee, UK Biomedical Research Centre Postdoctoral Fellow
- 2005 - 2008 JST-ERATO Environmental Response Project Postdoctoral Fellow
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Committee career (1)：
Awards (4)：
- 2015 - 日本生化学会東北支部 優秀論文賞
- 2015 - 東北大学医学部 奨学賞(銀賞)
- 2015 - 宮城県医師会 医学奨学賞
- 2008 - 第2回 JST-ERATO 環境応答国際シンポジウム ポスター賞
Association Membership(s) (4)：
日本ポリアミン学会
, 日本農芸化学会
, 日本生体防御学会
, 日本生化学会
