Rchr
J-GLOBAL ID:200901072654006074
Update date: Nov. 01, 2024
Hashimoto Yoshiya
ハシモト ヨシヤ | Hashimoto Yoshiya
Affiliation and department:
Research field (5):
Prosthodontics
, Environmental policy and society
, Environmental impact assessment
, Biomaterials
, Biomedical engineering
Research keywords (5):
ハイドロキシアパタイト
, 顎骨再生
, 歯周組織再生
, iPS細胞
, Enviromental Influence Assessment(including Radiobiology)
Research theme for competitive and other funds (46):
- 2024 - 2028 セノモルフィック核酸で調製したデザイナー高齢化幹細胞で創る新たな骨再生医療戦略
- 2024 - 2027 Drilling system to reduce bone cutting damage and improve osseointegration
- 2024 - 2027 血管内皮チューブ構造を有するiPS細胞由来マイクロスフェロイドを用いた歯周組織再生
- 2024 - 2027 老化細胞除去薬の徐放化によるインプラント周囲炎治療法の開発
- 2022 - 2026 New molecular mechanism of inhibition on bone regeneration evaluated using stress-induced aging model and RNA-seq analysis
- 2022 - 2025 垂直的骨造成のための細胞誘導因子徐放ハイドロゲルによる自己組織再生誘導
- 2020 - 2023 脱分化脂肪細胞由来エクソソームが拓く広域下顎骨骨欠損の再建
- 2020 - 2023 オーダーメイド唇顎口蓋裂治療に向けた織り構造足場材料の開発
- 2020 - 2023 ゼノフリーiPS細胞由来幹細胞の三次元細胞構造体が拓く骨再生医療
- 2019 - 2022 Er:YAG-パルスレーザーデポジション法のインプラント歯周炎治療への応用
- 2018 - 2022 ストレス誘導性老化細胞の挙動解析から迫る未知なる骨形成阻害機構の解明
- 2018 - 2021 Development of an osteoinductive biphasic hybrid bone substitute
- 2017 - 2020 Translational study of dedifferentiated fat cells from the buccal fat pad / PRP complex in in mandibular regeneration
- 2017 - 2020 Basic research for regeneration of wide-area mandibular bone defect using iPS cell-derived mesenchymal stem cells
- 2016 - 2020 Bone regeneration by the osteoclast suppression factor and porous TCP polymer complex for the treatment of cleft lip and palate
- 2016 - 2020 Widespread stomatognathic tissue defect regeneration using drug-loaded carrier and stem cells
- 2015 - 2019 Control and biological functionalization of biological aging of titanium surface by electrolytic reducing ionic water
- 2014 - 2018 Transportation research of dedifferentiated fat cells derived from the human buccal fat pad for maxillofacial cartilage regeneration
- 2013 - 2017 Fabrication of growth factor-sustained release scaffold for treating root apical lesion of root incomplete teeth
- 2013 - 2016 Development of drug release materials for bone regeneration
- 2013 - 2016 Development of guided tissue regeneration membrane with the control of nanoscale surface structure
- 2013 - 2016 Bone regeneration by hypertrophic cartilage cells using iPS cells as cell source
- 2010 - 2012 Development of bioactive orthodontic mini-screw with nano-apatite layer
- 2010 - 2012 stablishment of cell therapy in maxillary and mandibular bone tissue regeneration using canine induced pluripotent stem cells
- 2009 - 2011 Development of high strength. high modulus dental matrix resin with super-high cross-linked network structure
- 2008 - 2010 Roles of the claudin family of tight junction molecules in epithelial lumenformation of the submandibular gland
- 2008 - 2010 Implant treatment in next generation by preparation technology of nano apatite thin film
- 2008 - 2008 新規バイオリアクターを用いた簡易型培養骨作製システムの開発
- 2007 - 2008 siRNAによる歯周組織再生の試み
- 2007 - インジェクション型アルギン酸/TCPビーズ複合体を用いた新規骨再構築法の開発
- 2007 - 唾液バイオマーカーと遺伝子発現パターンによる高齢者ドライマウスの病態解明
- 2006 - 2006 優れた骨再生能と操作性を有するインジェクタブル人工骨の開発
- 2006 - 高齢者に優しい,マルチファンクショナルな義歯裏装材の開発
- 2006 - 新規ペプチドを用いたナノゲルエンジニアリングによる口腔乾燥の標的治療
- 2005 - レーザーアブレージョン法(ナノテク)を用いたアパタイト超薄膜インプラントの開発
- 2005 - ナノテクノロジーを応用した歯科用バイオセンサの開発
- 2004 - 自己組識誘導能を有する新規吸収性足場材料の開発
- 2003 - 可塑剤フリーの軟質裏装材の開発
- 2003 - 生体活性処理したチタンへの破骨細胞の接着と骨改造(in vitro)
- 2002 - レーザー照射によるインプラント表面改質の効果(in vitro)
- 2000 - 歯科材料成分の代謝を考えた内分泌攪乱作用の究明に関する研究(in vitro)
- 1994 - 歯科医療従事者の職業性アレルギーに関する調査研究
- The effect of laser annealing on HA implant
- The study of endocrine disruptor on dental materials.
- Biological Evaluation of New Glass Ionomer Cements
- In vitro cytotoxicity test under dynamic extraction
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Papers (186):
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張 若楠, 城 潤一郎, 西浦 亜紀, 本田 義和, 橋本 典也, 松本 尚之. Fisetinを被覆したTi-6Al-4VはRAW264の抗炎症作用を増強し破骨細胞分化能を抑制する. 日本歯科理工学会誌. 2024. 43. Special Issue82. 83-83
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Yufan Wu, Kengo Iwasaki, Yoshiya Hashimoto. Induction of mesenchymal stem cell (MSC) differentiation from iPS cells using MSC medium. Dental materials journal. 2024. 43. 1. 20-27
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Yuri Kuki, Kenzo Morinaga, Naoya Uemura, Tomoharu Okamura, Shigeki Hontsu, Yoshiya Hashimoto, Shunsuke Baba. Biocompatibility of dental implants coated with hydroxyapatite using pulsed Er:YAG laser deposition. Dental Materials Journal. 2024. 43. 2. 269-275
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Keiju Omatsu, Isao Yamawaki, Yoichiro Taguchi, Norimasa Tsumori, Yoshiya Hashimoto, Makoto Umeda. Surface modification affects human gingival epithelial cell behavior on polyetheretherketone surfaces. Dental Materials Journal. 2024. 43. 2. 191-199
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Yusuke Nishiguchi, Mamoru Ueda, Hirohito Kubo, Jun Ichiro Jo, Yoshiya Hashimoto, Toshihiko Takenobu. Optimized human dedifferentiated fat cells from the buccal fat pad-derived osteoinductive extracellular vesicles promote osteoblast differentiation. Journal of Dental Sciences. 2024
more...
MISC (86):
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松並智子, 今井弘一, 前岨亜優子, 中井真理子, 白井翼, 橋本典也. Cell Survival Rate using Three-dimensional Culture Technique with Type I Collagen on Three Commercially Pit and Fissure Sealants. 日本再生歯科医学会誌. 2024. 22. 1
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白井翼, 今井弘一, 中井真理子, 松並智子, 桝田康宏, 橋本典也. Cell Recovery by Exposure to Titanium and Zirconium Ions. 日本再生歯科医学会誌. 2024. 22. 1
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神田 龍平, 津田 進, 藤井 孝政, 柏木 宏介, 橋本 典也. Friedel-Craftsアシル化反応を用いたPEEK表面のカルボキシ化. 日本歯科理工学会誌. 2023. 42. Special Issue81. 80-80
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Tsubasa Shirai, Yoshiya Hashimoto, Koichi Imai. Study of cytotoxicity level by combining nanomaterials and chemical substances dissolved in culture medium. Nano Biomedicine. 2020. 12. 2. 120-124
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Koichi Imai, Yoshiya Hashimoto. Research targets of regenerative culture system. Nano Biomedicine. 2020. 12. 1. 39-42
more...
Patents (7):
Books (1):
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Cell-to-Materials Interaction-An Approach to Elucidate Biocompatibility of Biomaterials In Vitro(共著)
Biomaterials' Mechanical Properties. ASTM STP1173, Philadelphia 1994
Education (2):
- - 1990 Osaka Dental University Faculty of Dentistry
- - 1990 Osaka Dental University Faculty of Dentistry
Professional career (1):
- (BLANK) (Osaka Dental University)
Association Membership(s) (5):
日本補綴歯科学会
, 環境ホルモン学会
, 口腔組織培養研究会
, 大阪歯科学会
, 日本歯科理工学会
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