Murakami Yoshinori

ムラカミヨシノリ | Murakami Yoshinori

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://www.ims.u-tokyo.ac.jp/hitogan/index.html

Research field (2)： Hygiene and public health (laboratory) , Tumor diagnostics and therapeutics

Research keywords (9)： Genomic Medicine and Disease Prevention , 細胞接着 , がん抑制遺伝子 , 遺伝医学 , 分子腫瘍学 , Molucular Oncology , Genomic Medicine , DNA Diagnosis of Cancer , Tumor Suppressor Gene

Research theme for competitive and other funds (15)：

2022 - 2028 Platform of Supporting Cohort Study and Biospecimen Analysis
2022 - 2028 生命科学連携推進協議会
2022 - 2025 Elucidation of mechanisms of carcinogenesis, metastasis, and metabolism based on histological characteristics of HNF4alpha-positive lung adenocarcinoma
2020 - 2024 Development of novel diagnostic and therapeutic approaches to cancer by analyzing specific features of the immunoglobulin superfamily of molecules.
2021 - 2023 多層的生体情報の統合による疾患予防システムの構築

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Papers (133)：

Yue Guo, Yutaka Kasai, Yuto Tanaka, Yuki Ohashi-Kumagai, Takeharu Sakamoto, Takeshi Ito, Yoshinori Murakami. IGSF3 is a homophilic cell adhesion molecule that drives lung metastasis of melanoma by promoting adhesion to vascular endothelium. Cancer science. 2024
Anqi Wang, Jiayi Shen, Alex A. Rodriguez, Edward J. Saunders, Fei Chen, Rohini Janivara, Burcu F. Darst, Xin Sheng, Yili Xu, Alisha J. Chou, et al. Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants. Nature Genetics. 2023. 55. 12. 2065-2074
Go Sato, Yuya Shirai, Shinichi Namba, Ryuya Edahiro, Kyuto Sonehara, Tsuyoshi Hata, Mamoru Uemura, Yuji Yamanashi, Yoichi Furukawa, Takayuki Morisaki, et al. Pan-cancer and cross-population genome-wide association studies dissect shared genetic backgrounds underlying carcinogenesis. Nature Communications. 2023. 14. 1
Atsushi Kawamura, Koichi Matsuda, Yoshinori Murakami, Masayuki Saruta, Takashi Kohno, Kouya Shiraishi. Contribution of an Asian-prevalent HLA haplotype to the risk of HBV-related hepatocellular carcinoma. Scientific reports. 2023. 13. 1. 12944-12944
Yoshiyuki Akiyama, Kyuto Sonehara, Daichi Maeda, Hiroto Katoh, Tatsuhiko Naito, Kenichi Yamamoto, Koichi Matsuda, Yuji Yamanashi, Yoichi Furukawa, Takayuki Morisaki, et al. Genome-wide association study identifies risk loci within the major histocompatibility complex region for Hunner-type interstitial cystitis. Cell Reports Medicine. 2023. 4. 7

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MISC (160)：

Yunye He, Masaru Koido, Yoichi Sutoh, Mingyang Shi, Yayoi Otsuka-Yamasaki, Hans Markus Munter, Takayuki Morisaki, Akiko Nagai, Yoshinori Murakami, Chizu Tanikawa, et al. East Asian-specific and cross-ancestry genome-wide meta-analyses provide mechanistic insights into peptic ulcer disease. medRxiv. 2022
関根悠哉, 平田真, 鎌谷洋一郎, 松田浩一, 菅野康吉, 吉田輝彦, 村上善則, 赤松秀輔, 小川修, 沼倉一幸, et al. 腎がんの組織型に寄与する遺伝子が異なることを示した大規模ゲノム解析. 日本泌尿器科学会総会. 2021. 109回. AOP03-05
佐藤綾花, 田辺真彦, 坪井裕見, 牛久綾, 瀬戸泰之, 村上善則. BRAF V600E変異をもつ甲状腺乳頭癌においてctDNA検出は予後予測因子となる可能性がある. 日本癌学会総会記事. 2021. 80回. [P15-6]
関根悠哉, 平田真, 松田浩一, 菅野康吉, 吉田輝彦, 村上善則, 福井智洋, 赤松秀輔, 小川修, 中川英刀, et al. 腎細胞がんの組織型によって寄与する遺伝子が異なることを示した大規模ゲノム解析. 日本癌学会総会記事. 2021. 80回. [J7-1]
舩城桐子, 伊東剛, 後藤明輝, 仁木利郎, 松原大祐, 村上善則. 細胞接着分子CADM1は4.1Rを介して小細胞肺がんの悪性化を促進する. 日本癌学会総会記事. 2021. 80回. [P11-3]

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Patents (1)：

遺伝子異常検索法並びに遺伝子異常検索装置

Education (2)：

1977 - 1983 The University of Tokyo Faculty of Medicine School of Medicine
University of Tokyo, Faculty of Medicine

Professional career (1)：

M.D. & Ph.D. (The University of Tokyo)

Work history (20)：

2024/04 - 現在 Nippon Medical School Institute for Advanced Medical Sciences. Department of Molecular Biology Professor
2019/07 - 2024/03 The University of Tokyo The Institute of Medical Science, Project Division of Genomic Medicine and Disease Prevention Adjunctive Professor
2007/04 - 2024/03 The Institute of Medical Science, The University of Tokyo Division of MolecularPathology Professor
2015/04 - 2019/03 The University of Tokyo The Institute of Medical Science Dean
2000/07 - 2007/03 国立がんセンター研究所がん抑制ゲノム研究プロジェクトプロジェクトリーダー

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Awards (7)：

2013/02 - Princess Takamatsu Cancer Research Fund Academic Award
1998 日本癌学会、奨励賞
1992 日本肝臓学会、研究奨励賞
the Japanese Cancer Association
1998 Incitement Award of

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Association Membership(s) (10)：

米国人類遺伝学会 , 米国癌学会 , 日本分子生物学会 , 日本人類遺伝学会 , 日本癌学会 , American Society of Human Genetics , American Association of Cancer Research , Japanese Molecular Biological Society , Japanese Society of Human Genetics , Japanese Cancer Association

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