2020 - 2023 Development of minimally invasive therapy for oral cancer by hyperthermia with tumor-specific targeting magnetic nanoparticles
2019 - 2023 口腔癌におけるCaveolin-1 とIL-6の役割
2019 - 2023 Interrelationship analysis of the characteristics of quiescent tumor cells with tumor heterogeneity and cancer stem cell nature, referring to application to cancer therapy
2017 - 2021 Development of hyperthermia for the treatment of oral cancer using magnetite anti-EGFR antibody.
2017 - 2020 Mechanisms of immune modulation regulated by factors from OSCC cells on the development of acquiring metastatic potential to regional lymph nodes
2016 - 2019 Combination therapy using hyperthermia and IL-6 inhibitor for oral cancer
2015 - 2019 Efficacy of proton beam therapy for advanced oral cancer with cervical lymph node metastasis
2015 - 2019 A study on the prevention of oral cancer that targets the HIV-infected persons
2014 - 2018 Development of oral cancer treatment by hyperthermia generated with contrast agent Resovist and Cetuximab
2014 - 2018 Development of combination theray with hyperthermia and Interleukin-1 inhibitor.
2014 - 2017 Modulatory effect of fluvastatin upon immune suppression regulated by mesenchymal stromal cells and oral squamous cell carcinoma cells
2013 - 2017 Immunochemotherapy combined with hyperthermia for distant metastases of oral cancer using magnetic anticancer drug
2012 - 2016 Study on early detection and prevention of oral cancer for HIV infected people
2012 - 2015 Development of tailor-made intra-arterial chemotherapy using patient specific computational fluid dynamics
2011 - 2013 Prognosis of oral squamous cell carcinoma patients using gene expression profile and immunological status.
2011 - 2013 Overexpression of the atypical protein kinase C rambda/iota in oral squamous cell carcinoma is associated with degrees of malignancy
2011 - 2013 Development od multiimage-guided navigation system for superselective intra-arterial infusion for oral cancer
2011 - 2013 Effects of topical oral G-CSF on chemotherapy induced oral mucositis in cancer patients
2011 - 2012 Identification of cervical lymphatic drainage before and after chemoradiotherapy and detection of potential lymph node metastasis using ICG
2010 - 2012 Thermochemotherapy with controlled drug delivery using a novel magnetic anti-cancer drug
2009 - 2011 Effect of Concomitant use of G-CSF in bone regeneration by CD34 positive cells.
2009 - 2011 Analysis of optimal dose of anticancer drug in superselective intra-arterial infusion using computational fluid dynamics based on biomedical engineering
2008 - 2010 Elucidation of the mechanism for radioresistance from the viewpoint of gap junction using 3D-cultured cancer cells
2008 - 2010 Quantification of cell-free DNA in the plasma during radiation therapy
2007 - 2008 CD109 expression in the head and neck squamous cell carcinoma
2005 - 2007 Heat Immunotherapy using dendritic cell for squamous cell carcinoma
2004 - 2005 Gene therapy using lympho-epithelial Kazal-type-inhibitor (LEKTI) for head and neck cancer
2000 - 2001 A study of interstitial ihermoradiotherapy using powdered ferromagnetic body for oral cancer.
Toshinori Iwai, Satomi Sugiyama, Senri Oguri, Kenji Mitsudo. Endoscopically-assisted intraoral marginal mandibulectomy with a cutting guide for mandibular posterior gingival carcinoma. Journal of dental sciences. 2024. 19. 2. 1245-1247
Minamiyama S, Iwai T, Sugiyama S, Hirota M, Mitsudo K. A submandibular mass with parapharyngeal extension. Ear, Nose & Throat Journal. 2024
Iwai T, Ishikawa S, Ideta Y, Sugiyama S, Hayashi Y, Minamiyama S, Kitajima H, Mitsudo K. Limitation of PET/CT for screening of synchronous upper gastrointestinal cancer in oral cancer patients. J Oral Maxillofac Surg Med Pathol. 2024. 36. 2. 191-194