Ohno-Oishi Michiko

オオノミチコ | Ohno-Oishi Michiko

Research field (4)： Immunology , Applied biochemistry , Nutrition and health science , Applied molecular and cellular biology

Research keywords (6)：加齢性疾患 , 緑内障 , 熱ショックタンパク , 脂質代謝 , 老化 , ストレス応答

Research theme for competitive and other funds (5)：

2024 - 2027 ヒト緑内障GWASからの個別化創薬プラットフォーム構築研究
2022 - 2025 疾患関連マイクログリアクラスター制御による視神経保護治療
2014 - 2017 Identification of a homeostatic factor which restores age-related dysfunctions of mesenchymal stem/stromal cells
2012 - 2013 NASHにおける脂肪酸代謝異常とn-3PUFA摂取による予防・改善メカニズム
2008 - 2009 Studies on Role of the C-terminal region of Heat Shock Protein 72 in Innate immunity

Papers (27)：

Kazuki Okuyama, Motoi Yamashita, Artemis Koumoundourou, Christoph Wiegreffe, Michiko Ohno-Oishi, Samuel J H Murphy, Xin Zhao, Hideyuki Yoshida, Takashi Ebihara, Naoko Satoh-Takayama, et al. A mutant BCL11B-N440K protein interferes with BCL11A function during T lymphocyte and neuronal development. Nature immunology. 2024
Michiko Ohno-Oishi, Zou Meiai, Kota Sato, Seiya Kanno, Chihiro Kawano, Makoto Ishikawa, Toru Nakazawa. SH-SY5Y human neuronal cells with mutations of the CDKN2B-AS1 gene are vulnerable under cultured conditions. Biochemistry and Biophysics Reports. 2024. 38
Kota Sato, Daisuke Saigusa, Taiki Kokubun, Amane Fujioka, Qiwei Feng, Ritsumi Saito, Akira Uruno, Naomi Matsukawa, Michiko Ohno-Oishi, Hiroshi Kunikata, et al. Author Correction: Reduced glutathione level in the aqueous humor of patients with primary open-angle glaucoma and normal-tension glaucoma. npj aging. 2024. 10. 1. 8-8
Kota Sato, Yuto Sasaki, Michiko Ohno-Oishi, Kuniyuki Kano, Junken Aoki, Kosuke Ohsawa, Takayuki Doi, Hiroyuki Yamakoshi, Yoshiharu Iwabuchi, Chihiro Kawano, et al. New Dihydropyridine Derivative Attenuates NF-κB Activation via Suppression of Calcium Influx in a Mouse BV-2 Microglial Cell Line. The Tohoku Journal of Experimental Medicine. 2024
Kota Sato, Daisuke Saigusa, Taiki Kokubun, Amane Fujioka, Qiwei Feng, Ritsumi Saito, Akira Uruno, Naomi Matsukawa, Michiko Ohno-Oishi, Hiroshi Kunikata, et al. Reduced glutathione level in the aqueous humor of patients with primary open-angle glaucoma and normal-tension glaucoma. npj aging. 2023. 9. 1. 28-28

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MISC (33)：

佐藤孝太, 大石路子, 林宏亮, 中澤徹. Neuroprotective effect of hexokinase 2 against optic nerve injured mice. 日本眼科学会雑誌. 2024. 128
佐藤大夢, 石川誠, 大石路子, 神位りえ子, 佐藤孝太, 俵山寛司, 中澤徹. Changes in NLRP3 modulated by microglia in a rat ex vivo glaucoma model. 日本眼科学会雑誌. 2024. 128
OKUYAMA Kazuki, YAMASHITA Motoi, YAMASHITA Motoi, MATSUMOTO Kazuaki, MATSUMOTO Kazuaki, OHNO-OISHI Michiko, OHNO-OISHI Michiko, KOJO Satoshi, KOJO Satoshi, MORIO Tomohiro, et al. A do novo missense mutation of Bcl11b gene causes an abnormal thymopoiesis. 日本免疫学会総会・学術集会記録(CD-ROM). 2021. 50
佐藤孝太, 大石路子, 吉田真彰, 前川重人, 中澤徹. Rho-kinase involvement on microglial activation of mice retina by nerve crush. 日本眼科学会雑誌. 2021. 125
吉田真彰, 佐藤孝太, 大石路子, 市川惠一, 原精一, 五味恵子, 伊藤考太郎, 中澤徹. Neuroprotective effect of Selenoneine in cultured neurons. 日本緑内障学会抄録集. 2020. 31st

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Education (3)：

2002 - 2007 Kyoto University
2000 - 2002 Kyoto University
1996 - 2000 Doshisha Women's College of Liberal Arts Faculty of Human Life and Science

Professional career (1)：

博士(農学) (京都大学)

Work history (8)：

2021/04 - 現在東北大学大学院医学系研究科視覚先端医療学寄付講座学術研究員
2019/10 - 2021/03 Tohoku University University Hospital Ophthalmology
2017/04 - 2018/03 RIKEN
2015/04 - 2017/03 RIKEN
2013/04 - 2015/03 RIKEN

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Association Membership(s) (4)：

日本免疫学会 , 日本分子生物学会 , 日本生化学会 , 日本農芸化学会

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