Rchr
J-GLOBAL ID:200901072943373492   Update date: Nov. 06, 2023

Nishita Michiru

Nishita Michiru
Research field  (3): Developmental biology ,  Medical biochemistry ,  Cell biology
Research keywords  (5): 細胞移動 ,  Wntシグナル ,  細胞極性 ,  がん浸潤・転移 ,  cell biology
Research theme for competitive and other funds  (17):
  • 2021 - 2024 Wntシグナルに基づく新たな直腸癌化学放射線免疫複合療法の試み
  • 2020 - 2023 ゴルジ体微小管の構築制御に基づく癌細胞の集団的浸潤機構の解明
  • 2018 - 2020 がん細胞浸潤におけるゴルジ体内タンパク質輸送の分子機構
  • 2017 - 2020 Functional analysis of Ror1-Rif signaling in malignant progression of non-small cell lung cancer cells
  • 2016 - 2019 Analysis of molecular mechanisms of Wnt5a-Ror signaling in repair after tissue damage, inflammation, and cancer progression
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Papers (66):
  • Michiru Nishita, Koki Kamizaki, Kyoka Hoshi, Kana Aruga, Ikumi Nishikaku, Hiroshi Shibuya, Kunio Matsumoto, Yasuhiro Minami. Rho family small GTPase Rif regulates Wnt5a-Ror1-Dvl2 signaling and promotes lung adenocarcinoma progression. Journal of Biological Chemistry. 2023. 105248-105248
  • Takeshi Saji, Michiru Nishita, Kazuho Ikeda, Mitsuharu Endo, Yasushi Okada, Yasuhiro Minami. c-Src-mediated phosphorylation and activation of kinesin KIF1C promotes elongation of invadopodia in cancer cells. Journal of Biological Chemistry. 2022. 298. 7. 102090-102090
  • Daiki Okamoto, Natsuko Yamauchi, Gosuke Takiguchi, Michiru Nishita, Yoshihiro Kakeji, Yasuhiro Minami, Koki Kamizaki. Autonomous and intercellular chemokine signaling elicited from mesenchymal stem cells regulates migration of undifferentiated gastric cancer cells. Genes to cells : devoted to molecular & cellular mechanisms. 2022
  • Sonoda D, Kamizaki K, Matsuo Y, Aruga K, Mikubo M, Yamashita K, Nishita M, Minami Y, Satoh Y. Characterization of morphological alterations in micropapillary adenocarcinoma of the lung using an established cell line. Oncology reports. 2022. 47. 1
  • Alcantara MC, Suzuki K, Acebedo AR, Sakamoto Y, Nishita M, Minami Y, Kikuchi A, Yamada G. Stage-dependent function of Wnt5a during male external genitalia development. Congenital anomalies. 2021
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MISC (21):
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Patents (1):
  • コンディショナルノックアウト動物
Books (6):
  • Lippincott's Illustrated Reviews
    2019
  • Receptor Tyrosine Kinases: Family and Subfamilies
    Humana Press (Springer) 2015
  • Lippincott's Illustrated Reviews
    2015
  • Lippincott's Illustrated Reviews
    2011
  • Lippincott's Illustrated Reviews
    2008
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Lectures and oral presentations  (54):
  • Wnt5a-Rorシグナルが制御する細胞膜突起形成とがん細胞浸潤
    (第94回日本生化学会大会 2021)
  • Ror1-Rif signaling mediates filopodia formation to promote invasion and vasculogenic mimicry of lung adenocarcinoma cells.
    (第80回日本癌学会学術集会 2021)
  • Mesenchymal stromal cell-derived CXCL16 promotes proliferation and migration of gastric cancer cells by inducing STAT3-mediated expression of Ror1
    (ASCB/EMBO meeting 2019 2019)
  • Ror1 signaling through Dvl and Rif promotes invasion of lung adenocarcinoma cells
    (ASCB/EMBO 2019 meeting 2019)
  • 間葉系間質細胞由来のCXCL16は胃癌細胞においてSTAT3経路を介してRor1の発現を誘導し増殖と遊走を促進する
    (第78回日本癌学会総会 2019)
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Professional career (1):
  • 博士(薬学) (北海道大学)
Work history (7):
  • 2019/07 - 現在 Fukushima Medical University School of Medicine
  • 2007/10 - 2019/06 Kobe University Graduate School of Medicine
  • 2007/04 - 2007/09 神戸大学大学院医学系研究科・助教
  • 2004/04 - 2007/03 神戸大学大学院医学系研究科・助手
  • 2001/04 - 2004/03 日本学術振興会・特別研究員 (PD)(東北大学大学院生命科学研究科)
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Association Membership(s) (3):
日本癌学会 ,  日本生化学会 ,  日本分子生物学会
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