Rchr
J-GLOBAL ID:200901073831023886
Update date: Jan. 07, 2025
Yoshiyama Hironori
ヨシヤマ ヒロノリ | Yoshiyama Hironori
Affiliation and department:
Research field (2):
Virology
, Bacteriology
Research keywords (3):
ピロリ菌
, EBウイルス
, Virology Microbiology Molecular Biology
Research theme for competitive and other funds (18):
- 2024 - 2027 EBウイルス関連腫瘍及び重篤感染症の特異的治療薬の開発
- 2021 - 2024 Importance of cell differentiation and lytic viral replication in EBV-related epithelial tumor formation
- 2018 - 2021 Elucidation of EB virus-associated epithelial tumorigenesis by integrated understanding of in vitro and in vivo studies
- 2017 - 2021 B型肝炎ウイルス(HBV)感染サイクル(生活環)で機能する宿主・ウイルス因子を標的とした新規抗HBV剤・HBV感染制御法の開発
- 2016 - 2019 Research on relations between regional distribution of nasopharyngeal cancer and genomic polymorphism of Epstein-Barr virus for vaccine development
- 2016 - 2018 Characterization of exosomes released from Epstein-Barr virus-infected cells(Fostering Joint International Research)
- 2014 - 2017 Effect of H. pylori coinfection on genesis of EB virus associated gastric cancer
- 2013 - 2017 Proteomic analysis and genotyping of nontuberculosis mycobacteria to investigate effects of traditional Chinese medicines against pathogenesis
- 2011 - 2015 Molecular machineries of antitumor immune responses triggered by anticancer chemotherapy
- 2011 - 2013 Elucidation of oncogenic role of novel EBV latent genes
- 2005 - 2006 Research in mechanism of attachment and penetration of EB virus to the epithelial cell.
- 2003 - 2003 新規EBウイルスレセプターの性状解析
- 2001 - 2001 EBウイルスの上皮細胞トロピズムを決定する新規レセプター遺伝子のクローニング
- 1999 - 2000 Modification of Cell Signaling in EBV Infected Gastric Epithelial Cells by H. pylori.
- 1996 - 1997 Studies on the pathogenic factors of Helicobacter pylori.
- 1995 - 1995 EBウイルスベクターを用いたエイズワクチンに関する研究
- 1995 - 1995 HIV感染における中和抗体からのエスケープ変異出現の定量的解析
- 1994 - 1994 HIV中和単クローン抗体のエピトープの解析
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Papers (154):
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Amrizal Muchtar, Daichi Onomura, Dan Ding, Hironori Nishitsuji, Kunitada Shimotohno, Shunpei Okada, Keiji Ueda, Koichi Watashi, Takaji Wakita, Kei Iida, et al. MicroRNA-3145 as a potential therapeutic target for hepatitis B virus: inhibition of viral replication via downregulation of HBS and HBX. Frontiers in Microbiology. 2025. 15
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Aung Phyo Wai, Richardo Timmy, Kousho Wakae, Shunpei Okada, Masamichi Muramatsu, Hironori Yoshiyama, Hisashi Iizasa. Persistent Epstein-Barr Virus Infection of Epithelial Cells Leads to APOBEC3C Expression and Induces Mitochondrial DNA Mutations. Microbiology and Immunology. 2024
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Yuxin Liu, Aung Phyo Wai, Tumurgan Zolzaya, Yuichi Iida, Shunpei Okada, Hisashi Iizasa, Hironori Yoshiyama. Exploring the anti-EBV potential of suberoylanilide hydroxamic acid: induction of apoptosis in infected cells through suppressing BART gene expression and inducing lytic infection. Virology. 2024. 110161-110161
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Jun Nishikawa, Tomohiro Fujii, Soichiro Fukuda, Shoma Yoneda, Yuta Tamura, Yuki Shimizu, Akie Yanai, Yuki Kobayashi, Koji Harada, Keisuke Kawasaki, et al. Far-ultraviolet irradiation at 222 nm destroys and sterilizes the biofilms formed by periodontitis pathogens. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi. 2024
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Afifah Fatimah Azzahra Ahmad Wadi, Daichi Onomura, Hirokazu Funamori, Mst Mahmuda Khatun, Shunpei Okada, Hisashi Iizasa, Hironori Yoshiyama. Effects of Strain Differences, Humidity Changes, and Saliva Contamination on the Inactivation of SARS-CoV-2 by Ion Irradiation. Viruses. 2024. 16. 4. 520-520
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MISC (29):
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LIU Yuxin, IIZASA Hisashi, PHYO Wai Aung, AFIFAH Fatimah, KHATUN Mst. Mahmuda, MYAT Moe Thin, TUMURGAN Zolzaya, OKADA Shunpei, YOSHIYAMA Hironori. Tyrosine kinase inhibitor Dasatinib induces apoptosis more strongly in EB virus-infected gastric epithelial cells than in uninfected cells. 日本ウイルス学会学術集会プログラム・予稿集(Web). 2023. 70th
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飯笹久, 小野村大地, 小野村大地, LIU Yuxin, FATIMAH Afifah, 岡田俊平, 吉山裕規. miR-3145-3p is a viral suppressor induced by endoplasmic reticulum stress during hepatitis B virus replication. 日本ウイルス学会学術集会プログラム・予稿集(Web). 2023. 70th
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WADI Afifah Fatimah Azzahra Ahmad, 小野村大地, 小野村大地, 飯笹久, 岡田俊平, 吉山裕規. Effect of humidity and contaminated saliva for inactivation of SARS-CoV-2 by ion exposure. 日本ウイルス学会学術集会プログラム・予稿集(Web). 2023. 70th
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岡田俊平, KHATUN Mosammat Mahmuda, 飯笹久, 宇田川愛美, 上村尚人, 吉山裕規. Study on the SARS-CoV-2 discontinuous transcription mechanism important for distinct-size subgenomic RNA synthesis. 日本ウイルス学会学術集会プログラム・予稿集(Web). 2023. 70th
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PHYO Wai Aung, 飯笹久, 雨新, 小野村大地, 岡田俊平, 吉山裕規. ブレオマイシン誘導体ゼオシンは,EBV陽性胃がん細胞の細胞死を促進する. 日本ウイルス学会学術集会プログラム・予稿集(Web). 2022. 69th
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Patents (5):
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Epstein-Barr ウイルス関連癌に特異的な抗腫瘍剤
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VERPACKUNGSZELLSYSTEM FÜR DEN EB-VIRUSVEKTOR
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組換えEBウイルスの分離増殖法
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組換えEBウイルスの分離増殖法
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ヘリコバクター・ピロリ菌臨床分離株のβ-ラクタム系抗生物質アモキシシリン耐性に関与しているpbp1遺伝子の塩基配列とそれに基づいたアミノ酸配列の変異とその変異を有するヘリコバクター・ピロリ変異株およびそれらの診断と治療法開発への利用法
Books (15):
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EBウイルス関連胃癌 改訂第2版
診断と治療社 2022 ISBN:9784787825698
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Regulation of Epstein-Barr virus encoded microRNA in nasopharyngeal cancer cells
2021
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コンパクト微生物学 改訂第5版
南江堂 2021 ISBN:9784524226368
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標準微生物学 第14版
医学書院 2021 ISBN:9784260043311
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'Herpesviral microRNAs in cellular metabolism and immune responses': Shaping of Human Immune System and Metabolic Processes by Viruses and Microorganisms
Frontiers Media SA (ISBN: 978-2-88945-941-4) 2019
more...
Lectures and oral presentations (122):
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Bleomycin and Zeocin preferentially induce EBV-positive gastric cancer cell death.
(Viruses 2024 - A World of Viruses 2024)
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電離イオンのSARS-CoV-2不活化効果に、湿度変化と唾液混在が与える影響
(第70回日本ウイルス学会 2023)
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Tyrosine kinase inhibitor Dasatinib induces apoptosis more strongly in EB virus-infected gastric epithelial cells than in uninfected cells
(2023)
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miR-3145-3pはB型肝炎ウイルス複製に伴う小胞体ストレスが誘導するウイルス抑制因子である
(第70回日本ウイルス学会 2023)
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Study on the SARS-CoV-2 discontinuous transcription mechanism important for distinct-size subgenomic RNA synthesis
(2023)
more...
Professional career (1):
Work history (5):
- 2013/12 - 現在 Shimane University, Faculty of Medicine Department of Microbiology Professor
- 2000/05 - 2013/11 Hokkaido University, Institute for Genetic Medicine Research Center for Infection-associated Cancer Associate Professor
- 1995/07 - 2000/04 Yamaguchi University, School of Medicine Department of Microbiology, Lecturer
- 1993/04 - 1995/06 Yamaguchi University, School of Medicine Department of Virology Assistant Professor
- 1989/09 - 1993/03 The Rockefeller University Aaron Diamond AIDS Research Center Research Fellow
Committee career (7):
Awards (2):
- 1998/05 - 霜仁会学術振興賞本賞 T細胞持続感染系におけるEBウイルス初期遺伝子発現
- 1996/04 - 平成8年度日本消化器Helicobacter pylori学会基礎賞 Chemotaxis of Helicobacter pylori toward urea is independent of urease
Association Membership(s) (7):
日本小児科学会
, THE JAPANESE CANCER ASSOCIATION
, ヘルペスウイルス研究会
, 日本細菌学会中国・四国支部会
, 中国四国ウイルス学会
, 日本細菌学会
, 日本ウイルス学会
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