Rchr
J-GLOBAL ID:200901074443189280   Update date: Sep. 25, 2024

Hara Hirokazu

ハラ ヒロカズ | Hara Hirokazu
Affiliation and department:
Research field  (1): Pharmaceuticals - health and biochemistry
Research keywords  (2): 酸化ストレス、金属、細胞死 ,  Biopharmacology
Research theme for competitive and other funds  (20):
  • 2024 - 2029 Plasma-driven Sciences: Dynamics and transports of biochemically reactive species
  • 2020 - 2023 Dysfunction of neuronal cell caused by disruption of intracellular copper homeostasis
  • 2017 - 2020 Methylation dynamics in redox regulation - Elucidation of the molecular mechanisms of tumor metastasis
  • 2016 - 2019 Cell function control by plasma induced active particles -Academic foundation for safe plasma medicine-
  • 2017 - 2019 硫化水素の新規生理機能:金属イオン恒常性破綻による神経細胞傷害に対する保護作用
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Papers (90):
  • Tetsuro Kamiya, Nagisa Mizuno, Kaho Hayashi, Tomohiro Otsuka, Manami Haba, Naohito Abe, Masayoshi Oyama, Hirokazu Hara. Methoxylated Flavones from Casimiroa edulis La Llave Suppress MMP9 Expression via Inhibition of the JAK/STAT3 Pathway and TNFα-Dependent Pathways. Journal of agricultural and food chemistry. 2024. 72. 26. 14678-14683
  • Shu Tanaka, Sae Hayashi, Tomohiro Otsuka, Tetsuro Kamiya, Kenji Ishikawa, Hirokazu Hara. Inhibition of glutamine metabolism increases sensitivity to plasma-activated medium-induced cytotoxicity. Free radical research. 2024. 1-10
  • Yuki Inoue, Marina Ienaga, Tetsuro Kamiya, Tetsuo Adachi, Mitsuhiro Ohta, Hirokazu Hara. Royal jelly fatty acids downregulate ANGPTL8 expression through the decrease in HNF4α protein in human hepatoma HepG2 cells. Bioscience, biotechnology, and biochemistry. 2022. 86. 6. 747-754
  • Manami Haba, Naohito Abe, Tetsuro Kamiya, Nagisa Mizuno, Satoshi Okubo, Takao Yamaura, Hirokazu Hara, Masayoshi Oyama. Two new methoxylated flavones isolated from Casimiroa edulis La Llave and their MMP-9 inhibitory activity. Natural product research. 2022. 1-8
  • Tetsuro Kamiya, Yuji Yamaguchi, Manami Oka, Hirokazu Hara. Combined action of FOXO1 and superoxide dismutase 3 promotes MDA-MB-231 cell migration. Free radical research. 2022. 56. 1. 106-114
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MISC (57):
Education (4):
  • 1989 - 1994 Gifu Pharmaceutical University Graduate School Department of Pharmaceutical Science
  • - 1994 Gifu Pharmaceutical University Graduate School, Division of Pharmaceutical Sciences
  • 1985 - 1989 Gifu Pharmaceutical University Faculty of Pharmaceutical Science Department of Manufacturing Pharmacy
  • - 1989 Gifu Pharmaceutical University Faculty of Pharmaceutical Science
Professional career (1):
  • Ph.D. (Gifu Pharmaceutical University)
Work history (8):
  • 2021/04 - Gifu Pharmaceutical University
  • 2007 - 2021/03 Gifu Pharmaceutical University
  • 2005 - 2007 Gifu Pharmaceutical University
  • 1998 - 2005 Gifu Pharmaceutical University
  • 2002 - 2003 University of Pittsburgh
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Awards (1):
  • 2006/07 - 平成18年度日本薬学会東海支部学術奨励賞
Association Membership(s) (4):
北米神経科学会 ,  SOCIETY FOR FREE RADICAL RESEARCH JAPAN ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  THE PHARMACEUTICAL SOCIETY OF JAPAN
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