Rchr
J-GLOBAL ID：200901074908564750
Update date: Jun. 13, 2024
Nishida Atsushi
ニシダ アツシ | Nishida Atsushi
Affiliation and department：
Research field (1)：
Pharmaceuticals - chemistry and drug development
Research keywords (2)：
有機合成化学
, synthetic organic chemistry
Research theme for competitive and other funds (37)：
- 2017 - 2020 Medicinal Chemistry Based on the Total Synthesis of Polycyclic Alkaloids
- 2017 - 2019 Modification of trafficking/degradation of Ab protein by sphingolipids
- 2014 - 2019 Targeting ceramide synthase 6-dependent metastasis-prone phenotype in lung cancer cells
- 2014 - 2017 Regulatory mechanism of inflammation and mitochondrial function by galactolipids and SM
- 2013 - 2017 Synthetic Study of Polycyclic Natural Alkaloids and Application to Drug Development
- 2014 - 2016 Identification of cancer initiating cell factors and an attempt of drug development
- 2013 - 2016 Synthesis of double labeled ceramide fluorescent probes to analyze metabolism of sphingolipids
- 2011 - 2013 Development of reagents regulating metabolism of ceramide and aranidonic acid and its application to lung disorder
- 2009 - 2012 Development of Selective Method for Synthesis of Polycyclic NaturalProducts
- 2007 - 2008 光学活性(ビスアシルアミノ)ビナフタレンを配位子とする新規不斉合成反応の開発
- 2006 - 2007 海洋産マンザミンアルカロイドの不斉合成研究と機能解明
- 2005 - 2007 ナノテクノロジーを利用した半導体担持型有機金属触媒の開発
- 2006 - 2006 光学活性(ビスアシルアミノ)ビナフタレンを配位子とする新規不斉合成反応の開発
- 2005 - 2006 生理活性セラミドおよびスフィンゴシンリン酸プローブの開発と細胞死機能解明への応用
- 2004 - 2006 Synthesis of Biologically Active Alkaloids and Lead Compounds for Drug Development
- 2005 - 2005 海洋産マンザミンアルカロイドの不斉合成研究と機能解明
- 2002 - 2004 新規機能性金属錯体マテリアルの創出とキノリン・インドールライブラリー構築への展開
- 2002 - 2003 新規合成法の開発を基盤とする含窒素複素環天然物合成と生物活生物質の探索
- 2001 - 2002 DEVELOPMENT OF CATALYTIC ASYMMETRIC REACTIONS USING LANTANOIDS
- 2001 - 2001 新規合成法の開発を基盤とする含窒素複素環天然物合成と生物活性物質の探索
- 1999 - 2000 キニ-ネ・スフィンゴ脂質ハイブリッド構造を基本とする抗マラリア剤の開発
- 1999 - 2000 Synthesis of Antitumor Manzamine Alkaloid Isolated from Sponge and Development of Highly Bioactive Molecule
- 1999 - 2000 Synthesis of New Axially Chiral Ligand Library and Application to Asymmetric Synthesis of Biologically Active Compounds.
- 1998 - 1998 キニーネ・スフィンゴ脂質ハイブリッド構造を基本とする抗マラリヤ剤の開発
- 1996 - 1998 DEVELOPMENT OF ASYMMETRIC RADICAL REACTIONS AND APPLICATION TO THE SYNTHESIS OF BIO-ACTIVE COMPOUNDS
- 1992 - 1993 エリスロマイシンの化学変換とそれを用いるマクロリド抗生物質の作用機序の解明
- 1990 - 1993 Highly selective fine organic synthesis
- 1990 - 1990 カルボニル基を用いるラジカル環化反応:不斉環形成反応および骨格転移反応の開発
- 1990 - 1990 基底状態および励起状態における選択的電子移動複合体を経る反応の表発と応用
- 1988 - 1990 Synthesis of Macrolide and Polyether Antibiotics and Chemical Hybrids
- 1989 - 1989 基底状態および励起状態における選択的電子移動複合体を経る反応の開発と応用
- 生物活性含窒素化合物の合成,反応と機能
- ジアステレオ選択的ラジカル環化反応の開発
- 新規ラジカル骨格変換反応の開発
- Synthesis and Reaction of Biologically Active Compounds containing Nitrogen
- Development of Diastereoselective Radical Cyclization
- Development of New Radical Skeltal Rearrangement
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Papers (182)：
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Shinji Harada, Shihori Sekino, Marisa Inaba, Ayumi Okita, Tetsuhiro Nemoto, Shigeru Arai, Hitomi Ohmagari, Miki Hasegawa, Atsushi Nishida. Synthesizing Chiral Hydrocarbazoles with a Tetrasubstituted Carbon Using Holmium-Catalyzed Enantioselective [4 + 2] Cycloaddition: Mechanistic Insights from Luminescence and DFT Studies. The Journal of Organic Chemistry. 2024
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Natsuki Ito, Shigeru Arai, Atsushi Nishida. Construction of C2-C3 Contiguous Stereogenic Centers in Indoline Derivatives by 1,3-Dipolar Cycloaddition. Asian Journal of Organic Chemistry. 2024
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Shigeru Arai, Koichi Nakazawa, Xiao-Fei Yang, Masaya Nakajima, Shinji Harada, Atsushi Nishida. Nickel-catalysed regio- and stereoselective hydrocyanation of alkynoates and its mechanistic insights proposed by DFT calculations. Organic & Biomolecular Chemistry. 2024
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Shinji Harada, Ryuya Masuda, Takahiro Morikawa, Atsushi Nishida. Trichloromethylative Olefin Cycloamination by Photoredox Catalysis. European Journal of Organic Chemistry. 2021
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Yuna Kawata, Shigeru Arai, Masaya Nakajima, Atsushi Nishida. Regio- and stereoselective synthesis of cyclobutanes by nickel-catalyzed homodimerizative [2 + 2] cycloaddition using allenamides. Tetrahedron Letters. 2021. 69
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MISC (55)：
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Shigeru Arai, Yuka Amako, Hiroto Hori, Atsushi Nishida. Nickel-catalyzed hydrocyanation of carbon-carbon multiple bonds and its application. Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 2019. 77. 4. 341-350
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Shigeru Arai, Masaya Nakajima, Atsushi Nishida. Total synthesis of lundurines and related alkaloids. Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 2018. 76. 7. 668-677
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Shigeru Arai, Masaya Nakajima, Atsushi Nishida. Total Synthesis of Lundurine and Related Alkaloids: Synthetic Approaches and Strategies. Alkaloids: Chemistry and Biology. 2017. 78. 167-204
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Minoru Isobe, Atsushi Nishida, Yeun-Mun Choo, Noorsaadah Abd. Rahman, Poonsakdi Ploypradith, Somsak Ruchirawat, Guo-Qiang Lin, Ang Li, Zhu-Jun Yao, Biing-Jiun Uang, et al. The last and next decades of the asian core program on cutting-edge organic chemistry in asia. Chemistry - An Asian Journal. 2015. 10. 4. 790-804
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Mitsuhiro Arisawa, Atsushi Nishida, Satoshi Shuto. Design and synthesis of biologically active substituted indole compounds using enamide-ene metathesis. Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 2015. 73. 3. 254-265
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Education (4)：
- - 1979 Hokkaido University
- - 1979 Hokkaido University Graduate School, Division of Pharmaceutical Sciences
- - 1977 Hokkaido University Faculty of Pharmaceutical Sciences
- - 1977 Hokkaido University Faculty of Pharmaceutical Science
Professional career (1)：
Committee career (2)：
- 有機合成化学協会 関東支部幹事
- 日本薬学会 関東支部常任幹事
Awards (2)：
- 2020/03 - The Pharmaceutical Society of Japan The Pharmaceutical Society of Japan Award Synthetic Study of Polycyclic Natural Products Based on Development of New Strategy
- 2004/03 - The Pharmaceutical Society of Japan The Pharmaceutical Society of Japan Award for Divisional Scientific Promotion
Association Membership(s) (3)：
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