Ashida Hisashi

アシダヒサシ | Ashida Hisashi

Affiliation and department：
Job title：教授

Research field (5)： Applied microbiology , Food sciences , Applied biochemistry , Applied molecular and cellular biology , Entomology

Research keywords (19)：ビフィズス菌 , 乳酸菌 , 腸内細菌 , 応用微生物学 , 糖鎖生物学 , グリコシダーゼ , 食品機能学 , 食品工学 , 免疫学 , 細胞生物学 , オートファジー , 昆虫学 , 分類学 , 生物多様性 , Applied Microbiology , Food Science and Technology , Glycobiology , Cell Biology , Biodiversity

Research theme for competitive and other funds (18)：

2022 - 2026 Optimization for Zika virus oral mucosal vaccine using recombinant saccharomyces and lactobacilli
2023 - 2025 Analysis of the association between polyamine production in the scalp bacterial flora and hair growth.
2022 - 2025 Development of the prebiotics for bifidobacteria targeting plant polysaccharide-degrading pathway
2020 - 2023 Optimization of polyamine levels in the intestinal tract by controlling gut microbiota using lactic acid bacteria from traditional fermented foods
2018 - 2022 Basic research for development of oral mucosal vaccine against Zika virus infection using recombinant lactococcus and yeast

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Papers (121)：

Toma Kashima, Megumi Akama, Takura Wakinaka, Takatoshi Arakawa, Hisashi Ashida, Shinya Fushinobu. Crystal structure of Bifidobacterium bifidum glycoside hydrolase family 110 α-galactosidase specific for blood group B antigen. Journal of Applied Glycoscience. 2024
Hisashi Ashida. Kusumia kukai (Coleoptera, Carabidae, Trechinae), a New Species Found near Kôyasan in the Northern Part of the Kii Peninsula, Central Japan. Elytra, New Series. 2023. 13. 2. 175-180
Toshihiko Katoh, Chihaya Yamada, Michael D Wallace, Ayako Yoshida, Aina Gotoh, Moe Arai, Takako Maeshibu, Toma Kashima, Arno Hagenbeek, Miriam N Ojima, et al. A bacterial sulfoglycosidase highlights mucin O-glycan breakdown in the gut ecosystem. Nature Chemical Biology. 2023. 19. 778-789
Nobuya Wada, Hisashi Ashida. A New Species of the Genus Jujiroa (Coleoptera, Carabidae, Platyninae) from the Kii Peninsula, Central Japan. Elytra, Tokyo, New Series. 2022. 12. 2. 265-270
Rika Hirano, Aiko Kume, Chisato Nishiyama, Ryosuke Honda, Hideto Shirasawa, Yiwei Ling, Yuta Sugiyama, Misaki Nara, Hiromi Shimokawa, Hiroki Kawada, et al. Putrescine Production by Latilactobacillus curvatus KP 3-4 Isolated from Fermented Foods. Microorganisms. 2022. 10. 4. 697-697

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MISC (74)：

Lernaeenicus ramosus (Copepoda: Pennellidae) from a grub fish, Parapercis sexfasciata (Perciformes: Pinguiperidae), in the Kii Channel off the Pacific coast of central Japan. Nature of Kagoshima. 2024. 50. 209-212
Toma Kashima, Toshihiko Katoh, Chihaya Yamada, Takane Katayama, Hisashi Ashida, Shinya Fushinobu. Bifidobacterium bifidum由来の硫酸化ムチン糖鎖および血液型抗原分解酵素の構造基盤. Bulletin of Applied Glycoscience. 2023. 13. 4. 194-202
Hisashi Ashida, Kenji Yamamoto. Enzyme assay for β-N-acetylhexosaminidase. NCBI Bookshelf: Glycoscience Protocols (GlycoPODv2). 2023
Tomoya Shintani, Hideya Shintani, Masashi Sato, Hisashi Ashida. Calorie restriction mimetic drugs could favorably influence gut microbiota leading to lifespan extension. GeroScience. 2023
桝本麗花子, 芦田久, 片山高嶺, 加藤紀彦. 腸内細菌由来グリコシダーゼを用いたムチン脱グリコシル化のための酵素ツールの構築. 応用糖質科学. 2023. 13. 3

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Patents (7)：

エンドグリコセラミダーゼおよびその製造方法
リゾ糖脂質の製造方法
カリウムイオン測定用試薬組成物および試験片
体液中のマグネシウム測定用試験片
ガングリオシドの定量方法

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Books (10)：

Mucins. Methods in Molecular Biology
Springer US 2024 ISBN:9781071636695
糖鎖の新機能開発・応用ハンドブック〜創薬・医療から食品開発まで〜
株式会社エヌ・ティー・エス 2015
バイオ医薬品開発における糖鎖技術
シーエムシー出版 2011
Comprehensive Glycoscience Vol. 3
Elsevier 2007
Endoglycosidases -Biochemistry, Biotechnology, Application-
Kodansha/Springer 2006

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Lectures and oral presentations (112)：

地中性ゴミムシの採集法と最近の分類学的知見
(日本甲虫学会名古屋例会 2024)
In depth insight into the structure of a bifidobacterial multiple-domain enzyme that degrades type B blood group antigen
(CBM15 (Carbohydrate Bioengineering Meeting XV) 2024)
紀伊半島の地下浅層性・地中性ゴミムシについての最近の知見
(日本甲虫学会第39回大阪例会 2023)
Bifidobacterium bifidum degrades sulfated mucin O-glycans via a sulfatase-independent pathway
(GLYCO26 2023)
Bifunctional sialidase/β-N-acetylgalactosaminidase from bifidobacteria acting on Sda antigen/GM2
(Sialoglyco 2022 2022)

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Education (2)：

2000 - 2000 京都大学博士(農学) 農論2331号
1983 - 1988 Kyoto University Faculty of Agriculture

Professional career (1)：

Ph.D (Kyoto University)

Work history (10)：

2012/04 - 現在 Faculty of Biology-Oriented Science and Technology, Kinki University Professor
2008/06 - 2012/03 Kyoto University Graduate School of Biostudies
2006/01 - 2008/05 Kyoto University Graduate School of Biostudies
2004/04 - 2005/12 Osaka University Research Institute for Microbial Diseases
2001/09 - 2004/03 Osaka University Research Institute for Microbial Diseases

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Committee career (21)：

2021/07 - 現在日本応用糖質科学会近畿支部長
2019/09 - 現在日本応用糖質科学会評議員
2013 - 現在果実酒・果実飲料と健康に関する研究会世話人
2013 - 現在日本糖質学会評議員
2012/06 - 現在和歌山県立海南高等学校スーパーサイエンスハイスクール運営指導委員会委員・委員長

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Awards (3)：

2020/09 - 日本応用糖質科学会令和2年度日本応用糖質科学会学会賞ムチン糖鎖による宿主と腸内細菌の共生機構の解明
2012/03 - JSBBA Most-Cited Paper Award Prebiotic Effect of Lacto-N-biose I on Bifidobacterial Growth
2010/03 - JSBBA Topics Award

Association Membership(s) (8)：

JAPAN SOCIETY FOR LACTIC ACID BACTERIA , 日本甲虫学会 , 日本洞窟学会 , 日本進化学会 , 日本応用糖質科学会 , 日本糖質学会 , 日本農芸化学会 , 日本生化学会

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