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J-GLOBAL ID:200901075783647034   Update date: Feb. 01, 2024

Hayakawa Sumio

ハヤカワ スミオ | Hayakawa Sumio
Affiliation and department:
Research field  (3): Immunology ,  Medical biochemistry ,  Food sciences
Research keywords  (2): 分子生物学、自然免疫、食品栄養科学 ,  Food and Nutritional Sciences
Research theme for competitive and other funds  (12):
  • 2021 - 2025 細胞内コレステロールを基軸とした炎症慢性化の基盤的研究
  • 2020 - 2024 超分子を用いた腫瘍随伴マクロファージのリプログラミングと腫瘍成育微小環境の破壊
  • 2016 - 2019 Analysis of lipid metabolism regulation through chronic inflammation
  • 2014 - 2017 Activation of innate immune response by DNA from food
  • 2013 - 2017 Novel mechanisms of cellular antiviral defense through the PARP-13 shorter isoform, ZAPS
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Papers (41):
  • Mai Kato, Momoka Yamaguchi, Akira Ooka, Ryota Takahashi, Takuji Suzuki, Keita Onoda, Yuko Yoshikawa, Yuta Tsunematsu, Michio Sato, Yasukiyo Yoshioka, et al. Non-target GC-MS analyses of fecal VOCs in NASH-hepatocellular carcinoma model STAM mice. Scientific reports. 2023. 13. 1. 8924-8924
  • Yinglan Cheng, Ichiro Manabe, Sumio Hayakawa, Yusuke Endo, Yumiko Oishi. Caspase-11 contributes to site-1 protease cleavage and SREBP1 activation in the inflammatory response of macrophages. Frontiers in Immunology. 2023. 14
  • Anna Nakagawa, Sumio Hayakawa, Yinglan Cheng, Azusa Honda, Ryo Yuzawa, Rei Ogawa, Yumiko Oishi. Cyclic stretch regulates immune responses via tank-binding kinase 1 expression in macrophages. FEBS Open Bio. 2022
  • Sumio Hayakawa, Tomokazu Ohishi, Yumiko Oishi, Mamoru Isemura, Noriyuki Miyoshi. Contribution of Non-Coding RNAs to Anticancer Effects of Dietary Polyphenols: Chlorogenic Acid, Curcumin, Epigallocatechin-3-Gallate, Genistein, Quercetin and Resveratrol. Antioxidants. 2022. 11. 12. 2352-2352
  • Sumio Hayakawa, Atsushi Tamura, Nikita Nikiforov, Hiroyuki Koike, Fujimi Kudo, Yinglan Cheng, Takuro Miyazaki, Marina Kubekina, Tatiana V. Kirichenko, Alexander N. Orekhov, et al. Activated cholesterol metabolism is integral for innate macrophage responses by amplifying Myd88 signaling. JCI Insight. 2022. 7. 22
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MISC (9):
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Books (2):
  • Tea, Coffee and Health Benefits Bioactive Molecules in Food
    Springer International Publishing AG 2018
  • Health benefits of tea consumption, Beverage Impacts on Health and Nutrition
    Springer International Publishing, Switzerland 2016
Lectures and oral presentations  (11):
  • 自然免疫応答の調節機構
    (東京医科歯科大学 免疫学・病態生化学領域合同シンポジウム 2017)
  • 炎症シグナルが調節する脂質代謝調節機構
    (第6回Molecular Cardiovascular Conference II 2015)
  • ZAPSが担う自然免疫活性化のメカニズム
    (,平成23年度 北海道大学遺伝子病制御研究所 共同研究集会 2011)
  • ZAPSトランスジェニックマウスを用いた自然免疫応答の解析
    (日本ウイルス学会 北海道支部会 第45回 夏期シンポジウム 2011)
  • 自然免疫系における核酸認識受容体を介したシグナルの新規調節因子と抗ウイルス作用
    (第58回日本ウイルス学会 2010)
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Education (2):
  • 1999 - 2002 University of Shizuoka Graduate School of Nutritional and Environmental Sciences
  • 1997 - 1999 University of Shizuoka Graduate School of Nutritional and Environmental Sciences
Professional career (1):
  • (BLANK)
Work history (6):
  • 2022/10 - 現在 Nippon Medical School Department of Biochemistry and Molecular Biology,
  • 2018/04 - 2022/09 Nippon Medical School
  • 2014/04 - 2018/03 Tokyo Medical and Dental University Medical Research Institute
  • 2007/08 - 2014/03 Hokkaido University Institute for Genetic Medicine
  • 2003/04 - 2007/07 Kindai University Faculty of Medicine
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Association Membership(s) (3):
Japan Society of Nutrition and Food Science ,  Japanese Association for Food Immunology ,  日本生化学会
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