Yoko Akazawa

アカザワヨウコ | Yoko Akazawa

Affiliation and department：
Homepage URL (1)： http://www.aist.go.jp/RESEARCHERDB/cgi-bin/worker_detail.cgi?call=namae&rw_id=Y86123950

Research field (4)： Hygiene and public health (non-laboratory) , Hygiene and public health (laboratory) , Healthcare management, medical sociology , Molecular biology

Research keywords (3)：シングルドメイン抗体 , 神経変性疾患 , 酸化ストレス

Research theme for competitive and other funds (9)：

2020 - 2023 Establishment of innovative development scheme of anti-cancer antibody
2020 - 2023 免疫刺激によるシングルドメイン抗体の親和性成熟と抗原抗体複合体の物性変化の解明
2016 - 2019 Development of visualizing system of microRNA dynamism
2016 - 2018 シングルドメイン抗体に及ぼす異分子コンジュゲートの影響の検証
2014 - 2016 脂質酸化において生成する構造異性体種による細胞機能制御機構の解明

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Papers (29)：

Tomonari Matsuda, Yoko Akazawa-Ogawa, Lilian-Kaede Komaba, Norihiko Kiyose, Nobuo Miyazaki, Yusaku Mizuguchi, Tetsuo Fukuta, Yuji Ito, Yoshihisa Hagihara. Prediction of antigen-responding VHH antibodies by tracking the evolution of antibody along the time course of immunization. Frontiers in immunology. 2023. 14. 1335462-1335462
Masahiro Noji, Tatsushi Samejima, Keiichi Yamaguchi, Masatomo So, Keisuke Yuzu, Eri Chatani, Yoko Akazawa-Ogawa, Yoshihisa Hagihara, Yasushi Kawata, Kensuke Ikenaka, et al. Breakdown of supersaturation barrier links protein folding to amyloid formation. Communications Biology. 2021. 4. 1
Md. Golam Kibria, Yoko Akazawa-Ogawa, Yoshihisa Hagihara, Yutaka Kuroda. Immune response with long-term memory triggered by amorphous aggregates of misfolded anti-EGFR VHH-7D12 is directed against the native VHH-7D12 as well as the framework of the analogous VHH-9G8. European Journal of Pharmaceutics and Biopharmaceutics. 2021. 165. 13-21
Md Golam Kibria, Akari Fukutani, Yoko Akazawa-Ogawa, Yoshihisa Hagihara, Yutaka Kuroda. Anti-EGFR VHH Antibody under Thermal Stress Is Better Solubilized with a Lysine than with an Arginine SEP Tag. Biomolecules. 2021. 11. 6
Md. Golam Kibria, Yoko Akazawa-Ogawa, Nafsoon Rahman, Yoshihisa Hagihara, Yutaka Kuroda. The immunogenicity of an anti-EGFR single domain antibody (VHH) is enhanced by misfolded amorphous aggregation but not by heat-induced aggregation. European Journal of Pharmaceutics and Biopharmaceutics. 2020. 152. 164-174

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MISC (14)：

赤澤陽子, 松田知成, 宮崎誠生, 清瀬紀彦, 伊東祐二, 萩原義久. The predictions of high affinity single domain VHH antibody through repeated immunizations. 日本蛋白質科学会年会プログラム・要旨集. 2022. 22nd (Web)
小野陽介, 鶴田篤弘, 有馬一成, 伊東祐二, 赤澤陽子, 中島芳浩, 加藤太一郎. ホタル生物発光のアルパカ抗体による制御. 日本生物工学会大会講演要旨集. 2019. 71st
鶴田篤弘, 加藤太一郎, 有馬一成, 伊東祐二, 赤澤陽子, 中島芳浩. ホタルルシフェラーゼ生物発光活性制御におけるアルパカ抗体の利用. 日本生物工学会大会講演要旨集. 2018. 70th
鶴田篤弘, 加藤太一郎, 有馬一成, 伊東祐二, 赤澤陽子, 中島芳浩. アルパカ抗体を用いたホタルルシフェラーゼの発光活性制御. 生体触媒化学シンポジウム講演要旨集. 2017. 19th
佐竹貴莉子, 宮本結花, 岸本聡, 加藤由貴子, 加藤太一郎, 萩原義久, 赤澤陽子, 松田知成, 宮崎誠生, 清瀬紀彦, et al. 抗原免疫したアルパカVHH抗体ファージライブラリからの抗体フラグメント特異的VHH抗体の単離と特性解析. 日本生化学会大会(Web). 2016. 89th. ROMBUNNO.3P-355 (WEB ONLY)

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Patents (3)：

Association Membership(s) (1)：

PROTEIN SCIENCE SOCIETY OF JAPAN

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