Nishikawa Yuji

2016 - 2021 Advanced Animal Model Support

2017 - 2019 The effects of machine perfusion preservation for pig stentotic liver

2015 - 2017 Critical mechanisms for the determination of hepatocytic and bile ductular differentiation

2014 - 2017 Roles and mechanisms of JNK pathway in liver regeneration and tumor formation

2013 - 2016 Repair method of steatotic grafts aiming to resolve the organ shortage

2012 - 2016 Mutual plasticity between hepatocytes and bile ductular cells in ductular reaction - its significance and therapeutic implications

2013 - 2015 Hepaocyte injury induced by iron overload and its application for isolation of bile duct cells and stem cells

2012 - 2015 The role of mast cells in the pathophysiology of chronic pelvic pain syndrome

2011 - 2015 Investigation of pathogenesis of Fabry nephropathy in novel model mouse

2011 - 2014 光プローブを応用した生体イメージング法による画期的術中ライブ診断法の開発

2011 - 2012 Development of perfusion preservation method of liver graft, aiming to clinical application for liver transplantation using non-heart-beating-donor

2009 - 2011 Ductular metaplasia of hepatocytes : its demonstration in vivo and the study of the mechanism

2009 - 2011 Novel roles of connexin32 in expansion of cancer stem cell population and enhancement of metastasis

2008 - 2010 Significance of the integrin beta4 in the human prostate cancer

2006 - 2007 Suppression of hepatic ischemia-reperfusion injury by Bad siRNA deliverry

2006 - 2007 Roles of TNF-α in ductular metaplasia of hepatocytes

2004 - 2005 Roles of non-coding H19 mRNA in hepatocyte proliferation and differentiation

2001 - 2002 Phenotypic plasticity of mature hepatocytes: investigation of the mechanisms for aberrant cytokeratin 19 expression in hepatocytes

2001 - 2002 ギャップ結合による細胞増殖制御の新しい分子機構の解明

1999 - 2000 A Role of Protein Tyrosine Phosphorylation in Bile Ductular Metaplasia of Hepatocytes

1992 - 1994 Genetic Analysis of Paraffin-Embedded Human Tumor Samples by GC-clamped DGGE.

1990 - 1992 Transfection of the Albumin Promoter Driven-Oncogenes to Isolated Rodent Hepatocytes, and Transplantation of the Hepatocytes into Livers and Spleens of Syngenic Animals.

1990 - 1990 初代培養肝細胞におけるアルブミン遺伝子プロモーターによる癌遺伝子の発現

1988 - 1988 肝内移植法を用いた活性癌遺伝子の肝前癌細胞に対する働きの解析

肝細胞追跡系を用いた胆管発生および細胆管反応の研究

蛋白チロシンリン酸化調節による肝構成細胞の機能制御と肝疾患治療への応用

三次元培養系を用いた肝細胞の分化,増殖調節の研究

Basic studies on hepatic sinusoidal endothelial cells

Study on the mechanism of growth inhibition by vitamin K and its analogs

Study on the regulation of hepatocytic differentiation and proliferation