Uzawa Katsuhiro

2021 - 2024 Japan-US Research Collaboration on the Development of a Novel Therapeutic Strategy Targeting the Cancer-Associated Collagen to Overcome Treatment-Resistant Cancer Phenotypes

2020 - 2023 スーパーエンハンサーを標的とした口腔癌薬剤耐性機構の解明による治療法開発

2019 - 2022 Elucidation of the role of non-coding RNA adsorbed cyclic RNA in cancer growth invasion and metastasis.

2018 - 2020 Evaluate changes in collagen cross-linking in lysyl hydroxylase 2 knockout mice and elucidate the role of PLOD2 in cancer metastasis

2018 - 2020 Development study of normal salivary gland cell function maintenance, long-term mass culture method and completely new autotransplantation method

2017 - 2019 Development of novel strategy for molecular diagnosis/treatment via circular RNAs adsorbing cancer-associated miRNAs in peripheral blood and saliva from cancer patients

2017 - 2019 Development of siRNA / missile therapy using exosomes for oral cancer cells

2016 - 2018 千葉大学医学部附属病院先進医療開発推進経費

2015 - 2017 Development of a novel medicine for reducing side effects for cetuximab, a new therapeutic agent for head and neck cancer

2014 - 2017 Regeneration of muscle by introduction of MyoD family gene into adipose-derived stem cells

2016 - 2016 平成28年度千葉大学研究費獲得促進プログラム(多様型A)

2013 - 2015 Development of induction method using adipose-derived mesenchymal stem cells by transcription factor group for salivary gland differentiation

2013 - 2013 唾液腺細胞の継代安定培養法を用いた唾液分泌細胞再生療法の開発

2011 - 2013 Study on the expression status of CEA gene family in cancer and surrounding normal tissue and on the interaction between cancer and normal mesenchymal cells.

2011 - 2012 Development of the radioresistance conquest reinforcement therapy by an EGFR/FGFR dual inhibitor.

2010 - 2012 Cancer-targeted liposome coupled to viral proteins for imaging cancer cells

2011 - 2011 PDE3Bインヒビターを用いた抗癌剤治療増強法の開発

2008 - 2010 Total analysis of Pax family genes in oral carcinoma.

2007 - 2009 Development of cancer-targeted liposome with viral proteins

2005 - 2007 Profiling of mRNA and proteins in salivary gland tumors and search for the factors associated with carcinogenesis

2005 - 2006 マイクロアレイ・プロテオーム解析に基づく口腔粘膜疾患関連因子の検索

2004 - 2006 Identification of proteins associated with oral cancer by global proteomic approach.

2004 - 2005 Molecular biologic and histopathologic study on the expression status of Ca^<2+> binding protein genes in oral carcinoma

2004 - 2005 Construction of in-house cDNA microarrays for identifying radiotherapeutic molecular markers in human aquamous cell carcinoma

2003 - 2004 唾液腺組織のcDNAライブラリー作成と唾液腺疾患用DNAチップの開発作製

1993 - 2004 Tumor Suppressor Gene in Human Oral Cancer.

2002 - 2003 Study on the role of DNA methyltransferases in regulation of the expression of genes associated with the control of cell cycle

2001 - 2003 Reduced expression and hypermethylation of HEADPIN, a serine proteinase inhibitor (serpin) in human squamous cell carcinoma

2001 - 2003 Development of the diagnostic method to evaluate the risks for carcinogenesis, micro-metastasis, and malignant grade of oral cancer using in-house cDNA microarray

2001 - 2003 Development of the method to select the most effective anti-cancer chemotherapy using in-house cDNA microarray

2001 - 2003 In-house cDNA microarray analysis of gene expression profiles involved in SCC cell lines.

2001 - 2002 独自に開発したDNAチップを用いた発癌因子抵抗性評価および発癌予防法の開発

2000 - 2001 セメント質由来細胞を用いた歯周組織再生法の開発

1999 - 2001 Isolation of a novel tumor suppressor gene on the Chromosome 11 associated with oral squamous cell carcinoma.

1999 - 2001 Isolation of a novel tumor suppressor gene on the Chromosome 7 associated with oral squamous cell carcinoma.