Ozawa Toshihiko | Researcher Information

1997 - 3.活性酸素及び遊離基に対する生物学的防護剤の研究
1997 - 3.Studies on biological defence compounds against active oxygens and free radicals
1995 - 2.活性酸素及び遊離基に対する生物学的防御機構
1995 - 2.Studies on biological defence mechanisms against active oxygens and free radicals
1990 - 1.活性酸素及び遊離基のESR測定

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K Takeshita, K Fujii, K Anzai, T Ozawa. In vivo monitoring of hydroxyl radical generation caused by x-ray irradiation of rats using the spin trapping/EPR technique. FREE RADICAL BIOLOGY AND MEDICINE. 2004. 36. 9. 1134-1143
C Nishizawa, K Takeshita, JI Ueda, M Mizuno, KT Suzuki, T Ozawa. Hydroxyl radical generation caused by the reaction of singlet oxygen with a spin trap, DMPO, increases significantly in the presence of biological reductants. FREE RADICAL RESEARCH. 2004. 38. 4. 385-392
K Saito, K Takeshita, K Anzai, T Ozawa. Pharmacokinetic study of acyl-protected hydroxylamine probe, 1-acetoxy-3-carbamoyl-2,2,5,5-tetramethylpyrrolidine, for in vivo measurements of reactive oxygen species. FREE RADICAL BIOLOGY AND MEDICINE. 2004. 36. 4. 517-525
K Anzai, K Saito, K Takeshita, S Takahashi, H Miyazaki, H Shoji, MCI Lee, T Masumizu, T Ozawa. Assessment of ESR-CT imaging by comparison with autoradiography for the distribution of a blood-brain-barrier permeable spin probe, MC-PROXYL, to rodent brain. MAGNETIC RESONANCE IMAGING. 2003. 21. 7. 765-772
K Saito, K Takeshita, JI Ueda, T Ozawa. Two reaction sites of a spin label, TEMPOL (4-hydroxy-2,2,6,6-tetramethylpiperidine-N-oxyl), with hydroxyl radical. JOURNAL OF PHARMACEUTICAL SCIENCES. 2003. 92. 2. 275-280

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光学活性系ポリヒドロキシピロリジンとアレキシン異性体
ジチオカルバメート化合物とこれを含有する一酸化窒素捕捉用スピントラップ剤

Biodefence Mechanisms against Environmental Stress
Kodansha and Springer-Verlag, Tokyo and Heiderberg, 1998 1998
ビタミンE研究の進歩VIII
共立出版、東京、1998 1998
Effects of Hydroxyl Radicals and Peroxyl Radicals on Iron Permeability of Membranes.
Biological Oxidants and Antioxidants: Milecular Mechanisms and Health Effects, ed. by Lester Packer and Augustine S. H. Ong, AOC Press, USA 1998
Biodefence Mechanisms against Environmental Stress
Kodansha and Springer-Verlag, Tokyo and Heiderberg, 1998 1998
The Advance on the Vitamin E Research VIII
Kyouritsu Publication, Tokyo 1998 1998

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生体計測用ESRによる生体への酸化的ストレスの非侵襲的評価法の開発
1998 - 2004
Development on Non-invasive Evalution of Oxidative Stress by Invivo ESR
1998 - 2004

- 1974 The University of Tokyo
- 1974 The University of Tokyo Graduate School of Pharmaceutical Sciences
- 1968 The University of Tokyo Faculty of Pharmaceutical Sciences Department of Pharmacy
- 1968 The University of Tokyo Pharmaceutical Sciences

Doctor of Pharmaceutical Science (The University of Tokyo)

2000 - 2001 放射線科学総合研究所研究総務官
2000 - 2001 Dupty Director-General, NIRS
2001 - - 放射線科学総合研究所理事
2001 - - Exective Director, NIRS
1993 - 2000 放射線科学総合研究所部長

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2000 - 2002 日本薬学会理事
2000 - 2002 Pharmaceutical Society of Japan Director
2001 - 日本過酸化脂質・フリーラジカル学会評議員
2001 - 日本フリーラジカル学会(SFRR Japan) 理事
2001 - 電子スピンサイエンス学会理事

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2000 - 日本フリーラジカル学会学会賞(2000年)
2000 - The Society of Free Radical Research Japan Prize
1993 - 科学技術庁長官賞(1993年)
1993 - Director General of Science and Technology Agency Award
1990 - 日本薬学会奨励賞(1990年)

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日本過酸化脂質・フリーラジカル学会 , 日本薬学会 , 日本化学会 , 日本フリーラジカル学会(SFRR Japan) , 日本NO学会 , 電子スピンサイエンス学会 , The Japanese Society of Lipid Peroxide and Free Radical Research , Society for Free Radical Research(Japan) , Society for Free Radical Research(International) , Royal Society of Chemistry , Pharmaceutical Society of Japan , Nitric Oxide Society of Japan , New York Academy of Sciences , The Society of Electron Spin Science and Technology , Chemical Society of Japan , American Chemical Society