2003 - 2005 Overcome of virus-induced neurological disorders: analysis of neurological mechanisms inducing viral persistent infection in the central nervous system
2004 - 2004 新しい学習記憶障害モデル:ウイルス蛋白質を利用したシナプス脆弱化機構の解析
2002 - 2004 Studies on the heterogeneity in the correlation between Borna disease virus location in the central nervous system(CNS) and induced CNS pathogenesis
2003 - 2003 持続感染期におけるモノネガウイルス・ゲノムRNAの安定化機序の解析
2001 - 2002 ボルナ病ウイルス感染による神経突起伸張因子の機能阻害と脳成熟への影響
2001 - 2002 Regulation of Borna disease virus (BDV) phosphoprotein expression : Implication for BDV neuropathogenesis
2000 - 2000 パーキンソン病患者脳内神経細胞の破壊とボルナ病ウイルス感染
ウイルスを利用した脳発達異常と神経機能異常の発現機序に関する研究
内在性レトロウイルスの多様性に関する研究
ボルナ病ウイルスの神経病原性に関する研究
Studies on the mechanisms of Neurodevelopmental and neurobehavioral abnormalities using virus infections
Study on polymorphism of endogenous retrovirus
Study on neuropathogenesis of Borna disease virus
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Papers (210):
Ryo Komorizono, Shima Yoshizumi, Keizo Tomonaga. Development of an RNA virus-based episomal vector with artificial aptazyme for gene silencing. Applied Microbiology and Biotechnology. 2024. 108. 1
Masayuki Kitano, Hiroe Ohnishi, Akiko Makino, Tatsuo Miyamoto, Yasuyuki Hayashi, Keisuke Mizuno, Shinji Kaba, Yoshitaka Kawai, Tsuyoshi Kojima, Yo Kishimoto, et al. An Infection Model for SARS-CoV-2 Using Rat Transplanted with hiPSC-Airway Epithelial Cells. Tissue engineering. Part A. 2024
Yusa Akiba, Hiromichi Matsugo, Takehiro Kanda, Modoka Sakai, Akiko Makino, Keizo Tomonaga. A single amino acid substitution in the Borna disease virus glycoprotein enhances the infectivity titer of vesicular stomatitis virus pseudotyped virus by altering membrane fusion activity. 2024
Takehiro Kanda, Pauline Dianne Santos, Dirk Höper, Martin Beer, Dennis Rubbenstroth, Keizo Tomonaga. The absence of superinfection exclusion of Borna disease virus 2 maintains genomic polymorphisms in persistently infected cells. 2024
Kozue Murata, Akiko Makino, Keizo Tomonaga, Hidetoshi Masumoto. Predicted risk of heart failure pandemic due to persistent SARS-CoV-2 infection using a three-dimensional cardiac model. iScience. 2024. 27. 1. 108641-108641
後藤真也, 後藤真也, 平井悠哉, 朝長啓造, 朝長啓造, 朝長啓造, 野田岳志, 野田岳志, 堀江真行, 堀江真行, et al. Structural insights into the Borna disease virus 1 nucleoprotein-RNA complex assembly. 日本ウイルス学会学術集会プログラム・予稿集(Web). 2023. 70th
杉田征彦, 杉田征彦, 杉田征彦, 平井悠哉, 後藤真也, 後藤真也, 朝長啓造, 朝長啓造, 朝長啓造, 野田岳志, et al. Three-dimensional structures of the Borna disease virus 1 nucleoprotein-RNA complex. 日本ウイルス学会学術集会プログラム・予稿集(Web). 2023. 70th
岩本将士, 岩本将士, 柴田ゆき野, 川崎純菜, 小嶋将平, LI Yung-Tsung, 岩見真吾, 村松正道, WU Hui-Lin, 和多和宏, et al. Identification and characterization of novel deltaviruses revealed the diversity of strategy for deltavirus transmission. 日本ウイルス学会学術集会プログラム・予稿集(Web). 2021. 68th
Detection and functional elucidation of endogenous RNA viruses in the mammalian genomes.
(2021 Neo-Virology Symposium 2921)
Research Progress of orthobornaviruses in Kyoto University
(2022)
Bornavirus Research: Exploring the Neovirology.
(The University of Toledo, Department of Medical Microbiology & Immunology Seminar 2022)
A novel intranuclear RNA vector system targeting stem cells and the central nervous system
(The 16th International Symposium of the Institute Network for Biomedical Sciences. KEY FORUM 2021 International Symposium 2021)
- 1994 The University of Tokyo Graduate School, Division of Agriculture
- 1990 Kagoshima University Faculty of Agriculture
- 1990 Kagoshima University Faculty of Agriculture
Professional career (1):
Ph.D., D.V.M.
Work history (7):
2011/02 - 現在 Institute for Life and Medical Sciences (LiMe), Kyoto University Professor
2000/12 - 2011/01 Osaka University Research Institute for Microbial Diseases Associated Professor
1999/04 - 2000/11 Osaka University Research Institute for Microbial Diseases Assistant Professor
1998 - 1999 北海道大学免疫科学研究所 助手
1997 - 1998 アメリカ白血病協会 特別研究員(ボストン・タフツ大学)
1995 - 1997 日本学術振興会 海外特別研究員(ボストン・タフツ大学)
1994 - 1995 日本学術振興会 特別研究員(東京大学)
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Awards (8):
2017/11 - 第60回野口英世記念医学賞
2002 - 日本ウイルス学会杉浦奨励賞
2002 - Sugiura Encouragment Award of Japanese Society for Virology
1997 - アメリカ白血病協会・特別フェロー賞
1997 - Special Fellow Award of Lekemia Society of America
1994 - 日本獣医学会大会長賞
1994 - 日本獣医学会奨励賞
1994 - Encouragment Award of Japanese Society of Veterinary Science
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Association Membership(s) (8):
日本獣医学会
, 日本ウイルス学会
, 日本分子生物学会
, Japan Society of Gene and Cell Therapy
, RNA Society of Japan
, Society of Evolutionary Studies
, Japanese Society of Veterinary Science
, Japanese Society for Virology