FUMITAKA TAKESHITA

タケシタフミタカ | FUMITAKA TAKESHITA

Affiliation and department：
Job title： Chief
Homepage URL (1)： http://www.nccri.ncc.go.jp/s028/

Research field (4)： Experimental pathology , Pathobiochemistry , Cell biology , Molecular biology

Research keywords (3)： metastasis , tumor biology , RNA interference

Research theme for competitive and other funds (6)：

2023 - 2026 Development of novel therapeutic approach using serum exosomes to conquer bone metastases from lung cancer
2020 - 2023 Elucidation of molecular mechanism via NREF1 antisense RNA1 related to relapse of breast cancer
2009 - 2014 Medicinal Application of Functional Machinery for non-coding RNAs
2009 - 2014 Functional machinery for non-coding RNAs
2005 - 2009 Atelocollagen-mediated delivery of nucleic acid medicines

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Papers (102)：

吉岡祐亮, 竹下文隆, 横井暁, 落谷孝広, 落合孝広. ドラッグリポジショニングを用いた卵巣がん細胞のエクソソーム分泌抑制剤のスクリーニング(Drug repositioning screening for an inhibitor of EV secretion in ovarian cancer cells). 日本癌学会総会記事. 2023. 82回. 791-791
Masayuki Komatsu, Hitoshi Ichikawa, Fumiko Chiwaki, Hiromi Sakamoto, Rie Komatsuzaki, Makoto Asaumi, Kazuhisa Tsunoyama, Takeo Fukagawa, Hiromichi Matsushita, Narikazu Boku, et al. ARHGAP-RhoA signaling provokes homotypic adhesion-triggered cell death of metastasized diffuse-type gastric cancer. Oncogene. 2022
Marta Prieto-Vila, Wataru Usuba, Yusuke Yoshioka, Fumitaka Takeshita, Miki Yoshiike, Hideo Sasaki, Yusuke Yamamoto, Eiji Kikuchi, Takahiro Ochiya. High-grade bladder cancer cells secrete extracellular vesicles containing miRNA-146a-5p and promotes angiogenesis. Journal of Extracellular Biology. 2022. 1. 8
Fumihiko Urabe, Juntaro Matsuzaki, Fumitaka Takeshita, Takeshi Kishida, Takahiro Ochiya, Kotaro Hirai. Independent verification of circulating miRNA as diagnostic biomarkers for urothelial carcinoma. Cancer science. 2022
Seiichiro Abe, Juntaro Matsuzaki, Kazuki Sudo, Ichiro Oda, Hitoshi Katai, Ken Kato, Satoko Takizawa, Hiromi Sakamoto, Fumitaka Takeshita, Shumpei Niida, et al. A novel combination of serum microRNAs for the detection of early gastric cancer. Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association. 2021. 24. 4. 835-843

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MISC (35)：

Anna Sanchez Calle, Yumi Kawamura, Yusuke Yamamoto, Fumitaka Takeshita, Takahiro Ochiya. Emerging roles of long non-coding RNA in cancer. Cancer Science. 2018. 109. 7. 2093-2100
Kazuki Sudo, Ken Kato, Juntaro Matsuzaki, Junpei Kawauchi, Satoko Takizawa, Takahiro Miyamoto, Hirokazu Shoji, Satoru Iwasa, Yoshitaka Hon Ma, Atsuo Takashima, et al. Serum microRNAs to predict the response to nivolumab in patients with esophageal squamous cell carcinoma. JOURNAL OF CLINICAL ONCOLOGY. 2017. 35
高橋陵宇, 宮崎裕明, 竹下文隆, 山本雄介, 小野麻紀子, 田村研治. 乳がんにおけるがん幹細胞形質獲得機構の解明. 日本癌学会総会記事. 2015. 74回. E-1132
吉岡祐亮, 竹下文隆, 尾崎充彦, ギャイユスツ・リュク, 小坂展慶, 萩原啓太郎, 内野慧太, 落合孝広. マイクロRNAのがん治療および癌診断への応用がん抑制性miRNAを用いた治療への可能性(MicroRNA for cancer therapy and diagnosis Therapeutic applications of tumor suppressor miRNAs in cancer against cancer development). 日本癌学会総会記事. 2013. 72回. 41-41
Ryou-u Takahashi, Fumitaka Takeshita, Kimi Honma, Masaya Ono, Kikuya Kato, Takahiro Ochiya. Ribophorin II regulates breast tumor initiation and metastasis through the functional suppression of GSK3 beta. SCIENTIFIC REPORTS. 2013. 3. 3. 2474-2474

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Professional career (1)：

Ph.D. (Medical Science) (Nagoya City University, Graduate School of Medical Sciences)

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