Sasai Masaki

ササイマサキ | Sasai Masaki

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://www.tbp.cse.nagoya-u.ac.jp/

Research field (1)： Bio-, chemical, and soft-matter physics

Research keywords (9)：計算機シミュレーション , Computer simulations , Statistical mechanics , Stochastic processes , Gene network , Gene switch , Molecular motor , Allostery , Protein folding

Research theme for competitive and other funds (36)：

2022 - 2027 Principles of genome dynamics and DNA functions
2021 - 2023 4D genome architecture and transcription activity in cells
2020 - 2022 Stochastic thermodynamics of protein clock
2019 - 2022 ゲノム物理学-ゲノムの立体構造形成と運動の原理
2019 - 2021 相分離による分子液滴クラスター形成とクロマチン相互作用

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Papers (196)：

Shiori Iida, Satoru Ide, Sachiko Tamura, Masaki Sasai, Tomomi Tani, Tatsuhiko Goto, Michael Shribak, Kazuhiro Maeshima. Orientation-independent-DIC imaging reveals that a transient rise in depletion attraction contributes to mitotic chromosome condensation. Proceedings of the National Academy of Sciences of the United States of America. 2024. 121. 36. e2403153121
Tadasu Nozaki, Soya Shinkai, Satoru Ide, Koichi Higashi, Sachiko Tamura, Masa A Shimazoe, Masaki Nakagawa, Yutaka Suzuki, Yasushi Okada, Masaki Sasai, et al. Condensed but liquid-like domain organization of active chromatin regions in living human cells. Science advances. 2023. 9. 14. eadf1488
Takumi Nishina, Megumi Nakajima, Masaki Sasai, George Chikenji. The Structural Rule Distinguishing a Superfold: A Case Study of Ferredoxin Fold and the Reverse Ferredoxin Fold. Molecules. 2022. 27. 11. 3547-3547
Shin Fujishiro, Masaki Sasai. Generation of dynamic three-dimensional genome structure through phase separation of chromatin. Proc Natl Acad Sci USA. 2022. 119. 22. e2109838119
Masaki Sasai. Role of the reaction-structure coupling in temperature compensation of the KaiABC circadian rhythm. bioRxiv. 2021

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MISC (141)：

Sumita Das, Tomoki P. Terada, Masaki Sasai. Single-molecular and ensemble-level oscillations of cyanobacterial circadian clock. Biophysics and Physicobiology. 2018. 15. 136-150
Sumita Das, Tomoki P. Terada, Masaki Sasai. Role of ATP Hydrolysis in Cyanobacterial Circadian Oscillator. SCIENTIFIC REPORTS. 2017. 7
Masaki Sasai, George Chikenji, Tomoki P. Terada. Cooperativity and modularity in protein folding. Biophysics and Physicobiology. 2016. 13. 281-293-293
Tatsuya Okuno, Koya Kato, Shintaro Minami, Tomoki P. Terada, Masaki Sasai, George Chikenji. Importance of consensus region of multiple-ligand templates in a virtual screening method. Biophysics and Physicobiology. 2016. 13. 149-156-156
笹井理生, 寺田智樹. 真核細胞のルースな遺伝子制御とクロマチン動態. 生物物理. 2016. 56. 2. 106-108

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Books (14)：

タンパク質の時間と通信と自由エネルギー
丸善出版 2022
遺伝子スイッチのダイナミクス
丸善出版 2020
Modeling of genomes, Chapter 9 in Coarse-Grained Modeling of Biomolecules
CRC Press Taylor & Francis Group 2017
生体分子のつくるシステム
共立出版 2013 ISBN:9784320122727
論文にみる最重要概念と革新実験データその3
化学同人 2012

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Lectures and oral presentations (33)：

The role of dynamic cohesin looping in chromatin compaction and phase separation
(The 30th Hot Spring Harbor International Symposium 2022)
Stochastic dynamics of transcription and chromatin movement
(International Center for Theoretical Science Symposium 2020)
Protein Clock: How Chemical Free Energy is Used for Synchronization
(14th Asia-Pacific Physics Conference 2019)
The phase-separation principle of human genome folding
(CSRC Workshop on DNA Chromosome Structure and Dynamics 2017)
Role of Dynamical DNA Methylation in Gene Regulation
(International Conference on Biological Physics 2017 2017)

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Education (1)：

- 1985 Kyoto University Graduate School, Division of Natural Science

Professional career (2)：

理学博士 (京都大学)
Dr. Sci (Kyoto University)

Work history (24)：

2022/06 - 現在 Kyoto University Fukui Institute for Fundamental Chemistry
2022/04 - 現在 Nagoya University
2022/04 - 2023/03 Nagoya University Graduate School of Informatics
2017/04 - 2022/03 Nagoya University Graduate School of Engineering Applied Physics 3 Professor
2017/04/01 - 2018/03/31 Nagoya University School of Engineering / Graduate School of Engineering

2017/04/01 - 2018/03/31 Nagoya University Graduate School of Engineering Applied Physics

2017/04/01 - 2018/03/31 Nagoya University Graduate School of Engineering School of Engineering / Graduate School of Engineering

2011/04/01 - 2017/03/31 Nagoya University Graduate School of Engineering, Computational Science and Engineering

2011/04/01 - 2017/03/31 Nagoya University Graduate School of Engineering Department of Computational Science and Engineering Applied Computational Science and Engineering Professor

2014/04/01 - 2015/03/31 Nagoya University Graduate School of Engineering Department of Computational Science and Engineering

2012/04/01 - 2014/03/31 Nagoya University Graduate School of Engineering Center for Computational Science

2011/04/01 - 2013/03/31 Nagoya University University Library

2009/04/01 - 2011/03/31 Deoartment of Applied Physics, Nagoya University

2009/04/01 - 2011/03/31 Deoartment of Applied Physics, Nagoya University Graduate School of Engineering Department of Materials,Physics and Energy Engineering Professor

2006/04/01 - 2009/03/31 Professor, Department of Computational Science and Engineering, Graduate School of Engineering, Nagoya University

2006/04/01 - 2009/03/31 Professor, Department of Computational Science and Engineering, Graduate School of Engineering, Nagoya University Graduate School of Engineering Department of Computational Science and Engineering Professor

2003/04/01 - 2006/03/31 Professor, Department of Complex Systems Science, Graduate School of Information Science, Nagoya University

2006/03/31 - Nagoya University Graduate School of Information Science Department of Complex Systems Science Professor

2003/10 - 2006/03 Nagoya University Institute for Advanced Research Professor

1998/04/01 - 2003/03/31 Professor, Graduate School of Human Informatics, Nagoya University

1992/04/01 - 1998/03/31 Assistant Professor, Graduate School of Human Informatics, Nagoya University

1991/04/01 - 1992/03/31 Assistant Professor, College of General Education, Nagoya University Professor

1991/04/01 - 1992/03/31 Assistant Professor, College of General Education, Nagoya University

1985/08 - 1991/03/31 Research Associate, Institute for Molecular Science

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Committee career (12)：

2022/01 - 2024/12 Internationa Union of Pure and Applied Physics C6 (Biological Physics) Commission Chair
2017/10 - 2023/09 日本学術会議連携会員
2019/06 - 2021/05 日本生物物理学会監事
2018/01 - 2020/12 国際純粋及び応用物理学連合(IUPAP) Biological Physics Commission Seceretary
2017/12 - 2019/07 ICBP2019-EBSA joint conference Science Advisory Committee 委員

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Association Membership(s) (4)：

Biophysical Society , 日本蛋白質科学会 , 日本物理学会 , 日本生物物理学会

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