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J-GLOBAL ID：200901078866545712   Update date: Apr. 27, 2024

Ishihara Jun

イシハラ ジュン | Ishihara Jun
Affiliation and department：
Nagasaki University Graduate School of Biomedical Sciences, Pharmaceutical Sciences

About Nagasaki University Graduate School of Biomedical Sciences, Pharmaceutical Sciences


Job title： Professor
Research field  (3)： Pharmaceuticals - chemistry and drug development ,  Bioorganic chemistry ,  Structural/physical organic chemistry
Research keywords  (6)： 天然物合成 ,  海洋天然物 ,  天然物化学 ,  有機合成化学 ,  synthetic chemistry ,  organic chemistry
Research theme for competitive and other funds  (35)：
  • 2021 - 2022 高効率的合成に基づく微少多環性マクロリド天然物の創薬展開
  • 2018 - 2021 Efficient synthesis of mutifunctionalized cyclic compounds utilizing Lewis acid templates and its applications
  • 2020 - 2021 自己会合型触媒を用いる複雑な多環性天然物の迅速合成
  • 2018 - 2020 ルイス酸テンプレートを基軸とする多官能基化環状化合物の効率的合成とその応用展開
  • 2016 - 2019 Total Synthesis of Nitrogen-containing Macrocyclic Natural Products Useful for Drug Discovery
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Papers (135)：
  • Jun Ishihara. Progress in Lewis-Acid-Templated Diels-Alder Reactions. Molecules. 2024
  • Jun Takouda, Moeka Nakamura, Akane Murasaki, Waka Shimosako, Aoi Hidaka, Shino Honda, Susumu Tanimura, Fumito Ishibashi, Norihiko Kawasaki, Jun Ishihara, et al. Identification of Azalamellarin N as a Pyroptosis Inhibitor. Biological and Pharmaceutical Bulletin. 2024. 47. 1. 28-36
  • Keita KOMINE, Yuta YAMAZAKI, Taiga IWANAGA, Hikaru SAKAGUCHI, Hayato FUKUDA, Jun Ishihara. Visible-Light-Induced Three-Component Radical Coupling of Selenocarbamates, Enones, and Allylstannanes with Diphenyl(2,4,6-trimethylbenzoyl)phosphine Oxide. Synlett. 2023
  • Satoshi Mizuta, Masahiro Tabira, Naoki Shichiro, Tomoko Yamaguchi, Jun Ishihara, Takeshi Ishikawa. Reaction Mechanism and Origin of Stereoselectivity in the Fluorination and Trifluoromethylthiolation of 2-Bromoamides with AgF and AgSCF3. European Journal of Organic Chemistry. 2023
  • Jun Ishihara, Norihiko Kawasaki, Yu Kikuoka, Keita Komine, Hayato Fukuda. Concise Formal Synthesis on Solandelactone E Based on a Regioselective Cyclopropanation. HETEROCYCLES. 2023. 106. 2. 346-346
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MISC (52)：
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Patents (1)：
  • 新規キノリン誘導体およびこれを含有する有機触媒
Books (3)：
  • Marine natural products / Topics in Heterocyclic Chemistry 58
    Springer 2021 ISBN:9789811646362
  • Total Syntheses of (+)-Eremantholide A and (-)-Verrucarol : Form D-Glucose to Biologically Intriguing Sesquiterpenes
    Studies in Natural Products Chemistry 2000
  • Total Syntheses of (+)-Eremantholide A and (-)-Verrucarol : Form D-Glucose to Biologically Intriguing Sesquiterpenes
    Studies in Natural Products Chemistry 2000
Lectures and oral presentations  (41)：
  • タンデム反応に基づく多環性天然物の合成展開
    (九州大学 大学院理学附 特別講演会 2023)
  • タンデム反応に基づく多環性天然物の合成展開
    (九州大学 先導物質化学研究所 特別講演会 2023)
  • Recent Advances in the Total Synthesis of Macrocyclic Natural Products
    (7th Gratama Workshop 2023)
  • ペリ環状反応を基軸とする天然物合成の展開
    (API 講演会 2023)
  • Lewis Acid Template-Catalyzed Asymmetric Diels-Alder Reaction and Application to the Natural Products Synthesis
    (The 15th International Symposium on Organic Reactions (ISOR-15) 2022)
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Works (7)：
  • 特異な神経毒性を有する大環状アルカロイド、スピロライドの合成
    2009 - 2012
  • A New Variant of Reformatsky-Claisen Rearrangement Mediated by Indium Chloride
    2011 -
  • 特異な細胞機能制御活性を有する創薬リード天然物の高効率合成
    2008 - 2010
  • αーケトエステルを基質とする効率的置換クエン酸不斉構築法の開発
    2006 - 2008
  • 新規キレーション制御クライゼン転位反応を基軸とする天然物合成
    2005 - 2007
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Education (6)：
  • - 1993 Keio University
  • - 1993 Keio University Graduate School, Division of Engineering
  • - 1990 Keio University
  • - 1990 Keio University Graduate School, Division of Engineering
  • - 1984 Keio University Faculty of Science and Technology Department of Applied Chemistry
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Professional career (1)：
  • PhD (Keio University)
Work history (12)：
  • 2017/04/01 - Professor,Pharmaceutical Sciences,Pharmaceutical Sciences,Graduate School of Biomedical Sciences,Nagasaki University
  • 2008 - 2017/03/31 Associate Professor,Pharmaceutical Sciences,Pharmaceutical Sciences,Graduate School of Biomedical Sciences,Nagasaki University
  • 2008 - 2017 Nagasaki University Graduate School of Biomedical Sciences
  • 2010 - Chair, Universite de Haut-Alsace, ENSCMu
  • 2003 - 2008 Nagasaki University Graduate School of Biomedical Sciences
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Committee career (14)：
  • 2018 - 現在 複素環化学討論会世話人
  • 2018 - 現在 天然有機化合物討論会世話人
  • 2023/04 - 日本化学会 代表正会員
  • 2014 - 2018 有機合成化学協会 九州山口支部幹事
  • 2015 - 2016 日本薬学会 代議員
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Awards (3)：
  • 2020 - Nagase Science and Technology Foundation Nagase Science and Technology Award Synthesis of Functionalized Cyclic Natural Products by Self-Assembling Catalysts
  • 2005 - The Society of Synthetic Organic Chemistry, Japan Research Planning Award Synthetic Studies of Natural Products Using By a Chelation Controlled Claisen Rearrangement
  • 1999 - The Chemical Society of Japan Presentation Awards for young chemists Progress towards the Total Synthesis of Azadirachtin
Association Membership(s) (6)：
International Society of Heterocyclic Chemistry ,  日本コンピューター化学会 ,  有機合成化学協会 ,  日本薬学会 ,  American Chemical Society ,  日本化学会
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