Rchr
J-GLOBAL ID：200901078903008340   Update date: Oct. 23, 2023

Shimonaka Motoyuki

シモナカ モトユキ | Shimonaka Motoyuki
Affiliation and department：
Tokyo University of Science Faculty of Science Division I, Department of Chemistry

About Tokyo University of Science Faculty of Science Division I, Department of Chemistry


Homepage URL  (1)： http://www.rs.tus.ac.jp/mslab/
Research field  (3)： Clinical pharmacy ,  Physiology ,  Functional biochemistry
Research keywords  (2)： Regulation of angiogenesis ,  Molecular mechanism of hormone actions
Research theme for competitive and other funds  (2)：
  • 血管新生と血液凝固・線溶系の分子動態
  • Molecular dynamics of angiogenesis and coagulation/fibrinolysis
Papers (61)：
  • D Yamada, Y Kojima, A Hosoya, M Suzuki, T Watabe, T Inoue, N Tsugawa, T Asakawa, Y Yonemoto, M Onizawa, Y Nemoto, S Oshima, M Shimonaka, K Kuba, J Ishida, A Fukamizu, J M. Penninger, M Watanabe, R Okamoto, T Nagaishi. Apelin expression is downregulated in T cells in a murine model of chronic colitis. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2023. 647. 72-79
  • K Komatsuya, T Iguchi, M Fukuyama, I Kawashima, K Ogura, N Kikuchi, Y Shimoda, Y Takeda, M Shimonaka, N Yamamoto, N Sugiura, N Maeda, K Kasahara. Phosphacan acts as a repulsive cue in murine and rat cerebellar granule cells in a TAG-1/GD3 rafts-dependent manner. JOURNAL OF NEUROCHEMISTRY. 2022. 163. 5. 375-390
  • Kenichi Kitanishi, Motoyuki Shimonaka, Masaki Unno. Characterization of a Cobalt-Substituted Globin-Coupled Oxygen Sensor Histidine Kinase from Anaeromyxobacter sp. Fw109-5: Insights into Catalytic Regulation by Its Heme Coordination Structure. ACS Omega. 2021. 6. 50. 34912-34919
  • Shigehito Osawa,* Kenichi Kitanishi, Maho Kiuchi, Motoyuki Shimonaka, and Hidenori Otsuka*. Accelerated Redox Reaction of Hydrogen Peroxide by Employing Locally Concentrated State of Copper Catalysts on Polymer Chain. MACROMOLECULAR RAPID COMMUNICATIONS. 2021. 42. 16. e2100274
  • T Murata, T Kuboki, R Ishikawa, T Saito, S Taguchi, K Takeuchi, E Hatano, M Shimonaka, I Shiina. Total synthesis of violaceoid A and (-)- and (+)-violaceoid B. J NAT PROD. 2018. 81. 11. 2364-2370
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MISC (102)：
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Patents (4)：
  • 新規化合物及びその製造方法、並びに医薬組成物
  • BRAP2作用増強剤
  • BRAP2作用増強剤
  • プロテアソーム阻害剤抵抗性癌の細胞増殖抑制剤及びプロテアソーム阻害剤抵抗性癌の治療剤
Books (1)：
  • 教養化学
    丸善出版 2016
Lectures and oral presentations  (174)：
  • X線結晶構造解析に向けた好熱菌由来ガスセンサーホスホジエステラーゼの精製と結晶化
    (2023年度 日本生化学会関東支部例会 2023)
  • 抗腫瘍性化合物 M-COPA の改良合成ならびに類縁化合物の構造活性相関研究
    (日本化学会第103春季年会 2023)
  • BODIPY-FL を導入した蛍光標識型リダイフェン RID-B-BODIPY の合成研究
    (日本化学会第103春季年会 2023)
  • AMF-14 縮環部異性体の合成研究
    (日本化学会第103春季年会 2023)
  • 病原菌由来ガスセンサーホスホジエステラーゼのセンサードメインの構造解析
    (2022年度量子ビームサイエンスフェスタ(第14回MLFシンポジウム, 第40回PFシンポジウム) 2023)
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Education (2)：
  • - 1988 Tokyo Institute of Technology Graduate School, Division of Science and Engineering
  • - 1983 Tokyo Institute of Technology Faculty of Science
Professional career (1)：
  • Ph. D. (Tokyo Institute of Technology)
Work history (5)：
  • 1995 - 1996 Tokyo University of Science Assistant Professor
  • 1996 - Tokyo University of Science Associate Professor
  • 1991 - 1995 La Jolla Cancer Research Foundation Postdoctoral Fellow
  • 1989 - 1991 The Wittier Institute for Diabetes and Endocrinology Visiting Research Associate
  • 1988 - 1989 The Salk Institute for Biological Studies Visiting Research Associate
Committee career (7)：
  • 2019/11/01 - 2021/10/31 日本生化学会 代議員
  • 2017/11/01 - 2019/10/31 日本生化学会 代議員
  • 2014/10/01 - 2015/09/30 日本生化学会 代議員
  • 2012/10/01 - 2014/09/30 日本生化学会 代議員
  • 2010/10/01 - 2012/09/30 日本生化学会 関東支部 幹事
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Association Membership(s) (2)：
The Japanese Biochemical Society ,  日本生化学会
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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