Miyazaki Taisuke

ミヤザキタイスケ | Miyazaki Taisuke

Affiliation and department：
Homepage URL (1)： http://kaken.nii.ac.jp/ja/r/90374230

Research field (2)： Neuroanatomy and physiology , Neuroscience - general

Research keywords (17)：小脳 , グルタミン酸受容体 , プルキンエ細胞 , 登上線維 , 平行線維 , 神経標識法 , ルガロ細胞 , 遺伝子改変動物 , バスケット細胞 , 臨界期 , カルシウムイオン , 脳 , シナプス刈込み , シナプス回路 , 発達 , 大脳皮質 , シナプス

Research theme for competitive and other funds (9)：

2022 - 2025 Developmental neural circuit formation based on the competition between excitatory and inhibitory inputs in the cerebellum
2021 - 2025 Functional involvement of P/Q-type calcium channel in synapse elimination in adult brains
2020 - 2024 発達期からの慢性ニコチン曝露がもたらす神経回路変容の統合的理解
2017 - 2020 プルキンエ細胞シナプス後部におけるカルシニューリン依存的入力認識機構の解明
2012 - 2017 Molecular-anatomical research on multi-modal regulation of synaptic transmission in higher brain regions

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Papers (79)：

Ken-ichi Dewa, Nariko Arimura, Wataru Kakegawa, Masayuki Itoh, Toma Adachi, Satoshi Miyashita, Yukiko U. Inoue, Kento Hizawa, Kei Hori, Natsumi Honjoya, et al. Neuronal DSCAM regulates the peri-synaptic localization of GLAST in Bergmann glia for functional synapse formation. Nature Communications. 2024. 15. 1
Kohtarou Konno, Miwako Yamasaki, Taisuke Miyazaki, Masahiko Watanabe. Glyoxal fixation: An approach to solve immunohistochemical problem in neuroscience research. Science advances. 2023. 9. 28. eadf7084
Taisuke Miyazaki, Megumi Morimoto-Tomita, Coralie Berthoux, Kotaro Konno, Yoav Noam, Tokiwa Yamasaki, Matthijs Verhage, Pablo E Castillo, Masahiko Watanabe, Susumu Tomita. Excitatory and inhibitory receptors utilize distinct post- and trans-synaptic mechanisms in vivo. eLife. 2021. 10
Esther Suk King Lai, Hisako Nakayama, Taisuke Miyazaki, Takanobu Nakazawa, Katsuhiko Tabuchi, Kouichi Hashimoto, Masahiko Watanabe, Masanobu Kano. An Autism-Associated Neuroligin-3 Mutation Affects Developmental Synapse Elimination in the Cerebellum. Frontiers in neural circuits. 2021. 15. 676891-676891
Salm EJ, Dunn PJ, Shan L, Yamasaki M, Malewicz NM, Miyazaki T, Park J, Sumioka A, Hamer RRL, He WW, et al. TMEM163 Regulates ATP-Gated P2X Receptor and Behavior. Cell Rep. 2020. 31. 2. 107704-107704

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MISC (29)：

柿澤昌, 岸本泰司, 宮崎太輔, 田中碧, 村山尚, 渡辺雅彦, 飯野正光, 竹島浩. 新規カルシウム放出機構「一酸化窒素依存的カルシウム放出」と小脳依存性運動学習への関与. 日本NO学会学術集会プログラム抄録集. 2015. 15th. 52
Sho Kakizawa, Yasushi Kishimoto, Taisuke Miyazaki, Midori Tanaka, Takashi Murayama, Masahiko Watanabe, Masamitsu Iino, Hiroshi Takeshima. Involvement of Nitric oxide-induced calcium release in extinction of cerebellum-dependent motor learning. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. 100P-100P
相川知徳, 宮崎太輔, 三國貴康, 重本隆一, 若森実, 狩野方伸, 渡邊雅彦, 水澤英洋, 渡瀬啓. Cav2.1カルボキシル末端細胞質内ドメインの病態生理学的意義の検討. 臨床神経学. 2013. 53. 12. 1495-1495
Kobayashi S, Hida Y, Ishizaki H, Inoue E, Tanaka-Okamoto M, Yamasaki M, Miyazaki T, Fukuya M, Kitajima I, Takai Yoshimi, et al. The active zone protein CAST regulates synaptic vesicle recycling and quantal size. J Physiol Sci. 2013. 63. S67
Developmental switching of perisomatic innervation from climbing fibers to basket cell fibers in cerebellar Purkinje cells. 2012. 87. 2. 73-73

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Lectures and oral presentations (63)：

Carbonic anhydrase related protein Car8 is essential for the establishment of cerebellar neuronal circuit, regulating precise matching of pre and postsynapse in Purkinje cell.
(2021)
小脳抑制性介在ニューロンルガロ細胞の帯状構造特異的な入出力様式.
(生理学研究所研究会自閉症、てんかんの病態原理に関与するシナプス制御・神経回路機構 2021)
Principal rule of neurotransmitter receptor localization at synapse
(2019)
Compartmentalized input-output organization of cerebellar Lugaro cells, as revealed using knockin-mediated yellow cameleon reporter mice
(2019)
"Morphological classification of cerebellar interneurons and their connections"
("Synaptic Transmission Synaptic Transmission Gordon Research Conference" 2018)

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Professional career (1)：

博士(医学) (北海道大学)

Work history (3)：

2019/04 - 現在 Hokkaido University School of Medicine, Department of Health Sciences
2018/03 - 2019/03 Yale University School of Medcine, Department of Physiology Visiting Researcher
2012/04 - 2019/03 Hokkaido University

Awards (3)：

2020/09 - 日本解剖学会東北・北海道連合支部会学会賞小脳抑制性介在ニューロンルガロ細胞の帯状構造特異的な入出力様式
2017 - 北海道大学北海道大学医学部優秀論文賞 Glutamate transporter GLAST controls synaptic wrapping by Bergmann glia and ensures proper wiring of Purkinje cells
2009 - 日本解剖学会解剖学会奨励賞異種および同種入力線維間の競合を基盤とする小脳シナプス回路発達の分子機構に関する神経解剖学的研究

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