Rchr
J-GLOBAL ID：200901079034864431
Update date: Mar. 16, 2024
Taguchi Hiroyasu
タグチ ヒロヤス | Taguchi Hiroyasu
Affiliation and department：
Job title：
Special Contract Professor
Research field (1)：
Synthetic organic chemistry
Research theme for competitive and other funds (6)：
- 2019 - 2022 Development of novel ligands for in vivo imaging of amyloid oligomers in the brain of Alzheimer's disease
- 2019 - 2022 Microscopic analysis of amyloid beta oligomers to elucidate the function of candidate medicinal agents for Alzheimer's disease
- 2015 - 2019 Development novel probes for fluorine MRI to detect neurodegenerative diseases
- 2014 - 2017 Development of novel diagnostic and therapeutic methods on Alzheimer's disease by targeting amyloid oligomers
- 2010 - 2014 Development of amyloid imaging using fluorine-MRI
- 2007 - 2009 Development of diagnostic methods for Parkinson disease using high fieled magnetic resonance imaging
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Papers (107)：
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Asraa Faris Aldoghachi, Daijiro Yanagisawa, Aslina Pahrudin Arrozi, Zulzikry Hafiz Abu Bakar, Hiroyasu Taguchi, Shinsuke Ishigaki, Katsutaro Morino, Ikuo Tooyama. Fluorinated curcumin derivative (Shiga-Y6) modulates the level of thioredoxin-interacting protein (TXNIP) in a mouse model of diabetes. Biochemical and biophysical research communications. 2023. 694. 149392-149392
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Atsuya Matsui, Jean-Pierre Bellier, Daiki Hayashi, Takafumi Ishibe, Yoshiaki Nakamura, Hiroyasu Taguchi, Nobuyasu Naruse, Yutaka Mera. Curcumin tautomerization in the mechanism of pentameric amyloid- β42 oligomers disassembly. Biochemical and Biophysical Research Communications. 2023. 666. 68-75
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Ikuo Tooyama, Tomoko Kato, Hiroyasu Taguchi, Yusuke Kageyama, Kazuhiro Irie, Yukie Hirahara, Daijiro Yanagisawa. Visualization of Amyloid Oligomers in the Brain of Patients with Alzheimer’s Disease. ACTA HISTOCHEMICA ET CYTOCHEMICA. 2023
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柳沢 大治郎, 田口 弘康, 森川 茂廣, 遠山 育夫. ケト型クルクミン誘導体Shiga-Y51によるAβオリゴマーの画像化の検討. 老年精神医学雑誌. 2022. 33. 増刊II. 222-222
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柳沢 大治郎, 田口 弘康, 森川 茂廣, 遠山 育夫. ケト型クルクミン誘導体Shiga-Y51によるAβオリゴマーの画像化の検討. Dementia Japan. 2022. 36. 4. 742-742
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MISC (35)：
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柳沢 大治郎, 田口 弘康, 遠山 育夫. フッ素MRIによるアミロイドβ・タウ病理の画像化研究-Fluorin-19 MR imaging for detecting abnormal amyloid β and tau aggregates in the brain-特集 新規MRI計測・解析技術の認知症への応用. Dementia Japan : 日本認知症学会誌 / 日本認知症学会誌編集委員会 編. 2022. 36. 3. 440-447
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Molecular imaging for dementia using fluorine-MRI. 2021. 35. 3. 346-354
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加藤智子, 柳沢大治郎, 田口弘康, 白井伸明, 平尾浩一, 曾我部孝行, 富山貴美, 蒲生恵三, 平原幸恵, 北田容章, et al. アルツハイマー病におけるAβオリゴマーに結合するケト型クルクミン化合物の可能性. Dementia Japan. 2021. 35. 4
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柳沢大治郎, 田口弘康, 遠山育夫. フッ素MRIによるアミロイドβ・タウ病理の画像化研究. Dementia Japan. 2021. 35. 4
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遠山育夫, 柳沢大治郎, 田口弘康. MRIを用いた認知症の分子イメージング. Dementia Japan. 2020. 34. 4
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Education (3)：
- - 1972 The Australian National University
- - 1964 Nagoya University School of Science Department of Chemistry
- - 1964 Nagoya University Faculty of Science
Professional career (1)：
Work history (6)：
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