Rchr
J-GLOBAL ID：200901079760910949   Update date: Jun. 24, 2024

Tomoyoshi Soga

ソガ トモヨシ | Tomoyoshi Soga
Affiliation and department：
Keio University Faculty of Environment and Information Studies

About Keio University Faculty of Environment and Information Studies


Job title： Professor
Homepage URL  (2)： http://www.iab.keio.ac.jp/ ,  http://www.iab.keio.ac.jp/en/index.html
Research field  (1)： Systems genomics
Research theme for competitive and other funds  (33)：
  • 2021 - 2024 Spatio-temporal trans-omics analysis of metabolic control mechanisms of multi-cellular organ systems
  • 2021 - 2024 Mitochondrial Medicine
  • 2018 - 2023 Development of risk prediction models for mild cognitive decline and frailty using metabolomics in a population-based cohort
  • 2021 - 2022 Development of novel therapy targeting SUCLA2 deficiency in advanced prostate cancer
  • 2019 - 2021 Drug development targeting metabolic vulnerability of SUCLA2 deletion
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Papers (385)：
  • Salim, F, Mizutani, S, Shiba, S, Takamaru, H, Yamada, M, Nakajima, T, Yachida, T, Soga, T, Saito, Y, Fukuda, S, et al. Fusobacterium species are distinctly associated with patients with Lynch Syndrome colorectal cancer. iScience. 2024. 27. 7. 110181-110181
  • Tabata, S, Endo, H, Makinoshima, H, Soga, T, Inoue, M. The γ-glutamyl cycle serves as an amino acids supply system in colorectal cancer organoids under chronic hypoxia. Biochem. Biophys. Res. Commun. 2024. 714. 149977-149977
  • Fukuda, H, Arai, K, Mizuno, H, Nishito, Y, Motoi, N, Arai, Y, Hiraoka, N, Shibata, T, Sonobe, Y, Kayukawa, Y, et al. Molecular subtypes of lung adenocarcinoma present distinct immune tumor microenvironments. Cancer Sci. 2024. 115. 6. 1763-1777
  • Katsuumi, G, Shimizu, I, Suda, M, Yoshida, Y, Furihata, T, Joki, Y, Hsiao, CL, Jiaqi, L, Fujiki, S, Abe, M, et al. SGLT2 inhibition eliminates senescent cells and alleviates pathological aging. Nat. Aging. 2024. online
  • Nagao, M, Oshima, M, Suto, H, Sugimoto, M, Enomoto, A, Murakami, T, Shimomura, A, Wada, Y, Matsukawa, H, Ando, Y, et al. Serum Carbohydrate Antigen 19-9 and Metabolite Hypotaurine Are Predictive Markers for Early Recurrence of Pancreatic Ductal Adenocarcinoma. Pancreas. 2024. 54. 4. e301-e309
ｍore...
MISC (176)：
  • Saito, Y, Soga, T. 腫瘍における分岐鎖アミノ酸トランスポーターの役割. Experimental Medicine. 2022. 40. 14. 2239-2244
  • Saito, Y, Soga, T. アミノ酸トランスポーターを標的とした個別化医療. Precision Medicine. 2021. 4. 13. 18-22
  • 北島正二朗, 曽我朋義. メタボロミクスによるがん幹細胞の代謝研究. (別冊 医学のあゆみ) 治療標的としてのがん幹細胞. 2021. 117-121
  • Hara, Y, Sugawara, A, Yamada, KC, Endo, K, Ashitani, S, Igarashi, K, Soga, T, Shinjo, A, Kuroda, H. Comprehensive Measurement and Comparison of Ionic Small Molecules Contained in Citrus Unshiu Marc. Using Metabolomic Analysis. JOURNAL OF THE JAPANESE SOCIETY FOR FOOD SCIENCE AND TECHNOLOGY. 2020. 67. 12. 499-513
  • Soga, T, Sugimoto, M. メタボローム解析に基づく癌診断法の開発. Gastroenterology & Hepatology. 2020. 8. 2. 137-143
ｍore...
Patents (26)：
  • Method of Creating Spray Device for Sheathless CE-MS, Spray Device for Sheathless CE-MS, And Sheathless CE-MS Device
  • シースレスCE-MS用スプレーデバイスの作成方法、シースレスCE-MS用スプレーデバイス、及び、シースレスCE-MS装置(Method of Creating Spray Device for Sheathless CE-MS, Spray Device for Sheathless CE-MS, And Sheathless CE-MS Device)
  • Liver Disease Marker, Method and Apparatus for Measuring Same, And Test Method for Pharmaceutical Preparation
  • Method Of Creating Spray Device For Sheathless CE-MS, Spray Device For Sheathless CE-MS, And Sheathless CE-MS Device
  • Liver Disease Marker, Method and Apparatus for Measuring Same, And Test Method for Pharmaceutical Preparation
ｍore...
Books (25)：
  • (別冊・医学のあゆみ)メタボローム解析UPDATE
    医歯薬出版株式会社 2020
  • (別冊・医学のあゆみ) メタボローム解析UPDATE
    医歯薬出版株式会社 2020
  • Cancer Biology Illustrated
    Yodosha 2019 ISBN:9784758120968
  • (医学のあゆみ)メタボローム解析UPDATE
    医歯薬出版株式会社 2019
  • Amino Acid Analysis : Methods and Protocols
    Humana Press 2019 ISBN:9781493996384
ｍore...
Lectures and oral presentations  (437)：
  • One minute メタボロミクス解析への挑戦
    (第42回キャピラリー電気泳動シンポジウム(SCE2022) 2022)
  • 1分メタボロミクスへの挑戦
    (第16回メタボロームシンポジウムin 鶴岡 2022)
  • がんと代謝
    (第25回日本がん免疫学会総会 2021)
  • 最新のCE-MSメタボローム測定技術
    (第40回キャピラリー電気泳動シンポジウム(SCE2020) 2020)
  • 高感度、高速メタボローム解析技術の開発とがん研究
    (第93回日本生化学会大会 2020)
ｍore...
Works (3)：
  • キャピラリー電気泳動による無機陰イオン、有機酸、アミノ酸の分析
    そがともよし 2001 - 現在
  • 経済産業省主催「バイオ人材育成事業」メタボローム実習講師
    SOGA TOMOYOSHI 2004 - 2004
  • 日経BP社主催バイオファイナンスギルド メタボローム講座
    SOGA TOMOYOSHI 2004 -
Education (1)：
  • 1980 - 1984 Keio University Faculty of Engineering Applied Chemistry
Professional career (1)：
  • Ph.D. (Toyohashi University of Technology)
Work history (17)：
  • 2022/04 - 現在 Graduate School of Media and Governance, Keio University Professor
  • 2013/04 - 現在 RIKEN Center for Sustainable Resource Science(CSRS) Senior Visiting Scientist
  • 2010/04 - 現在 Technical Advisory Board, Human Metabolome Technologies Inc.
  • 2008/04 - 現在 School of Medicine, Keio Univ. Professor
  • 2006/04 - 現在 Keio University Faculty of Environmental Information/ Institute for Advanced Biosciences, Professor
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Awards (10)：
  • 2022/11 - Keio Univ. Fukuzawa Award
  • 2015/11 - Division of Electrophoresis, Japan Society for Analytical Chemistry The 2nd Shigeru Terabe Award CE-MSメタボローム測定技術の開発と実用化
  • 2011/11 - Keio University Keio Award CE-MSメタボローム測定技術の開発と実用化
  • 2010/11 - 酸化ストレスと肝研究会 第7回酸化ストレスと肝研究会 奨励賞 メタボロミクスによる新規酸化ストレスマーカーの同定と肝臓疾患スクリーニング
  • 2009/07 - Japan Institute of Invention and Innovation The prize of the chairman of HATSUMEI KYOKAI Apparatus and Method for Metabolome Analysis
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