Ikuta Koichi

イクタコウイチ | Ikuta Koichi

Affiliation and department：
Job title： Professor
Homepage URL (1)： https://www2.infront.kyoto-u.ac.jp/Ikuta-Lab/

Research field (3)： Immunology , Pathobiochemistry , Medical biochemistry

Research keywords (10)： innate lymphoid cell , innate-like lymphocyte , glucocorticoid , sex hormone , circadian rhythm , lymphocyte , microenvironment , IL-7 receptor , cytokine receptor , cytokine

Research theme for competitive and other funds (43)：

2023 - 2026 Control of immune response and tissue homeostasis by novel IL-15-dependent innate lymphocytes
2020 - 2023 IL-15-producing microenvironment supporting innate lymphoid cells and its role in diseases
2020 - 2022 Induction of autoimmune diseases by glucocorticoids
2017 - 2019 Regulation of immune microenvironment by IL-15-expressing cells in vivo
2016 - 2019 Control of innate immune cells, chronic inflammation and infection by cytokine-producing immune microenvironment

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Papers (169)：

Akihiro Shimba, Shizue Tani-Ichi, Kyoko Masuda, Guangwei Cui, Satoru Munakata, Shinya Abe, Satsuki Kitano, Hitoshi Miyachi, Hiroshi Kawamoto, Koichi Ikuta. A Chimeric IL-7Rα/IL-2Rβ Receptor Promotes the Differentiation of T Cell Progenitors into B Cells and Type 2 Innate Lymphoid Cells. Journal of immunology (Baltimore, Md. : 1950). 2024
Shizue Tani-ichi, David Obwegs, Alice Yoshikawa, Hitomi Watanabe, Satsuki Kitano, Aki Ejima, Shinya Hatano, Hitoshi Miyachi, Guangwei Cui, Akihiro Shimba, et al. A RORE-dependent Intronic Enhancer in the IL-7 Receptor-α Locus Controls Glucose Metabolism via Vγ4+ γδT17 Cells. The Journal of Immunology. 2024. 213. 3. 283-295
Koichi Ikuta, Takuma Asahi, Guangwei Cui, Shinya Abe, Daichi Takami. Control of the Development, Distribution, and Function of Innate-Like Lymphocytes and Innate Lymphoid Cells by the Tissue Microenvironment. Advances in experimental medicine and biology. 2024. 1444. 111-127
Guangwei Cui, Shinya Abe, Ryoma Kato, Koichi Ikuta. Insights into the heterogeneity of iNKT cells: tissue-resident and circulating subsets shaped by local microenvironmental cues. Frontiers in immunology. 2024. 15. 1349184-1349184
Shinya Abe, Takuma Asahi, Takahiro Hara, Guangwei Cui, Akihiro Shimba, Shizue Tani-Ichi, Kohei Yamada, Kazuko Miyazaki, Hitoshi Miyachi, Satsuki Kitano, et al. Hematopoietic cell-derived IL-15 supports NK cell development in scattered and clustered localization within the bone marrow. Cell reports. 2023. 113127-113127

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MISC (71)：

CUI Guangwei, 生田宏一. Circulating iNKT cells mediate antiviral and antitumor immunity. 医学のあゆみ. 2023. 286. 3
榛葉旭恒, 生田宏一. 【免疫系の概日リズム】グルココルチコイドによる免疫応答能の概日制御. 医学のあゆみ. 2022. 281. 2. 159-163
谷一靖江, 生田宏一. 【γδT細胞による生体制御】γδT細胞の恒常性維持機構. 炎症と免疫. 2022. 30. 3. 212-214
谷一靖江, 生田宏一. 〈Basic Science〉γδT細胞による生体制御 γδT細胞の恒常性維持機構. 炎症と免疫. 2022. 30. 3
山本れいこ, JIN Jianshi, CUI Guangwei, 竹内直志, 宮内栄治, 北條望, 大野博司, 大野博司, 生田宏一, 城口克之. Influence of vitamin A deficiency on the mouse gut microbiota revealed by our newly developed method,“BarBIQ”. 腸内細菌学雑誌. 2022. 36. 2

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Books (2)：

Role of the IL-7 receptor in γδ T-cell development from hematopoietic stem cells
In “Hematopoietic Stem Cell Biology”. Kondo, M., ed. Humana Press Inc. pp143-159 2009
Developmental potential of fetal hematopoietic stem cells.
In " Hematopoietic stem cells: Biology and therapeutic applications". Levitt, D. J., and Mertelsmann, R. eds. pp69-83. 1995

Lectures and oral presentations (124)：

ストレスはグルココルチコイドを介してTh17細胞の分化を促進し腸炎を増悪させる
(Kyoto T Cell Conference 第30回学術集会 2021)
ステロイドホルモンによる免疫機能とアレルギーの制御
(日本アレルギー学会学術集会、JSA-JSI Joint Session 2021)
胎児肝臓に由来する1型自然リンパ球の同定
(Kyoto T Cell Conference 第30回学術集会 2021)
Circadian control of immunity by glucocorticoid
(2020)
免疫学の視点からコロナ時代を見る
(東京大学医学部医学序論連続講座シリーズXX「医の原点」 2020)

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Education (4)：

1984 - 1987 Kyoto University Graduate School of Medicine
1983 - 1984 Osaka University Graduate School of Medicine
1979 - 1983 The University of Tokyo Faculty of Medicine School of Medicine
1977 - 1979 The University of Tokyo College of Arts and Sciences

Professional career (1)：

Doctor of Medicine (Kyoto University)

Work history (9)：

2022/04 - 現在 Kyoto University Institute for Life and Medical Institute Professor
2016/10 - 2022/03 Kyoto University Institute for Frontier Life and Medical Sciences Professor
2002/04 - 2016/09 Kyoto University Institute for Virus Research Professor
1996/07 - 2002/03 Kyoto University Graduate School of Medicine Associate Professor
1992/03 - 1997/03 The University of Tokyo Faculty of Medicine Visiting Associate Professor

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Committee career (4)：

2003 - 現在日本生化学会評議員
1997 - 現在日本免疫学会評議員
2005 - 2010 日本免疫学会学会のあり方検討委員会委員
2000 - 2005 日本免疫学会教育推進委員会委員

Awards (1)：

2002 - 日本免疫学会賞

Association Membership(s) (3)：

日本生化学会 , 日本分子生物学会 , 日本免疫学会

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