Ohno Yoshiya

オオノヨシヤ | Ohno Yoshiya

Affiliation and department：
Job title： Associate Professor

Research field (1)： Immunology

Research theme for competitive and other funds (9)：

2021 - 2024 IL-18が誘導するI型免疫応答と腫瘍ネオ抗原による免疫チェックポイントの制御
2016 - 2023 ナフトピジルを基盤とした新規悪性中皮腫治療薬の創製と作用メカニズムの解明
2019 - 2022 Overcoming immune-related adverse events (irAE) induced by immune checkpoint inhibitors
2018 - 2021 Regulation of immune-checkpoint by IL-18 and its application to cancer immunotherapy
2013 - 2016 Tissue-specific trafficking of immune-competent cells mediated by lymph node-associated cell trafficking signals and regulation of immune-responses towards self components.

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Papers (14)：

Natsumi Hayashi, Akitaka Yamasaki, Shiho Ueda, Shogo Okazaki, Yoshiya Ohno, Toshiyuki Tanaka, Yuichi Endo, Yoshihisa Tomioka, Kazue Masuko, Takashi Masuko, et al. Oncogenic transformation of NIH/3T3 cells by the overexpression of L-type amino acid transporter 1, a promising anti-cancer target. Oncotarget. 2021. 12. 13. 1256-1270
Eri Manabe, Satoyasu Ito, Yoshiya Ohno, Toshiyuki Tanaka, Yoshiro Naito, Naoko Sasaki, Masanori Asakura, Tohru Masuyama, Masaharu Ishihara, Takeshi Tsujino. Reduced lifespan of erythrocytes in Dahl/Salt sensitive rats is the cause of the renal proximal tubule damage. Scientific Reports. 2020. 10. 1
Ito Satoyasu, Ohno Yoshiya, Tanaka Toshiyuki, Kobuchi Shuhei, Ayajiki Kazuhide, Manabe Eri, Masuyama Tohru, Jun-Ichi Sakamoto, Tsujino Takeshi. Neutrophil/lymphocyte ratio elevation in renal dysfunction is caused by distortion of leukocyte hematopoiesis in bone marrow. Renal failure. 2019. 41. 1. 284-293
Ohno Yoshiya, Shingyoku Serina, Miyake Sakina, Tanaka Aya, Fudesaka Sena, Shimizu Yuta, Yoshifuji Ai, Yamawaki Yuki, Yoshida Sachiyo, Tanaka Saya, et al. Differential regulation of the sphere formation and maintenance of cancer-initiating cells of malignant mesothelioma via CD44 and ALK4 signaling pathways. Oncogene. 2018. 37. 49. 6357-6367-6367
Yuta Hara, Ryota Torii, Shiho Ueda, Erina Kurimoto, Eri Ueda, Hiroshi Okura, Yutaka Tatano, Hideki Yagi, Yoshiya Ohno, Toshiyuki Tanaka, et al. Inhibition of tumor formation and metastasis by a monoclonal antibody against lymphatic vessel endothelial hyaluronan receptor 1. Cancer science. 2018. 109. 10. 3171-3182

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MISC (2)：

今井一貴, 上田詩歩, 大野喜也, 石渡俊行, 益子高. テトラスパニン遺伝子破壊による膵癌エクソソーム分泌の機能解析(Analysis of exosome secretion from pancreatic cancers by knockout of tetraspanin genes). 日本癌学会総会記事. 2018. 77回. 2442-2442
田中稔之, 大野喜也. 血球のトラフィッキング~分子基盤から病態まで~1.免疫担当細胞のホーミング. 血液フロンティア. 2013. 23. 10. 1371-1380

Books (1)：

免疫ぺディア
2017

Lectures and oral presentations (22)：

マウス大腸癌細胞における mIFNGR1 シグナルの役割
(第67回日本薬学会近畿支部総会・大会 2017)
マウスがん細胞の in vivo 増殖における PD-L1 の役割
(第67回日本薬学会近畿支部総会・大会 2017)
IL-18 による免疫チェックポイント阻害剤の作用増強における CD122 陽性細胞の関与
(第67回日本薬学会近畿支部総会・大会 2017)
Activin-Aとヒアルロン酸を介するALDH陽性悪性中皮腫細胞の維持機構
(第67回日本薬学会近畿支部総会・大会 2017)
Jurkat を用いた T 細胞遊走に関する研究
(第66回日本薬学会近畿支部総会・大会 2016)

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Work history (2)：

2023/04 - 現在 Hyogo Medical University School of Pharmacy
2018/12 - 2023/03 Hyogo University of Health Sciences School of Pharmacy, Department of Pharmacy

Association Membership(s) (5)：

日本薬学会 , 日本免疫学会 , 日本癌学会 , 日本がん免疫学会 , 日本がん転移学会

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