Matsuda Akio

Matsuda Akio | Matsuda Akio

Affiliation and department：
Job title： Chief

Research field (4)： Immunology , Fetal medicine/Pediatrics , Allergies and connective tissue disease , Oral medicine (pathology)

Research keywords (5)： Allergy , Cytokine , inflammation , Kawasaki disease , vascular endothelial cells

Research theme for competitive and other funds (10)：

2022 - 2025 難治性川崎病血管炎の新しい制御方法の開発
2021 - 2024 Investigation of the relationship between complement and pediatric vasculitis; the possibility of anti-complement therapy as a novel treatment
2021 - 2023 Establishment of the molecular mechanism for the indefinite complaint caused by tissue dysfunction caused due to vascular damage
2018 - 2020 免疫グロブリン製剤(IVIG)の抗冠動脈炎症の分子メカニズム解明に基づく、IVIG不応川崎病症例に対する新規治療薬開発を目指した研究
2017 - 2017 免疫グロブリン治療の冠動脈炎症に対する抗炎症分子作用メカニズムの解明

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Papers (95)：

Kenichiro Motomura, Hideaki Morita, Naoko Okada, Akio Matsuda, Susumu Nakae, Mikiya Fujieda, Haruhiko Sago, Hirohisa Saito, Kenji Matsumoto. Comprehensive Analysis of the Expression and Functions of Pattern Recognition Receptors in Differentiated Cytotrophoblasts Derived from Term Human Placentas. Journal of immunology (Baltimore, Md. : 1950). 2023. 210. 10. 1552-1563
Kyoko Saito, Keisuke Orimo, Terufumi Kubo, Masato Tamari, Ayako Yamada, Kenichiro Motomura, Hiroki Sugiyama, Ryo Matsuoka, Naoko Nagano, Yuka Hayashi, et al. Laundry detergents and surfactants-induced eosinophilic airway inflammation by increasing IL-33 expression and activating ILC2s. Allergy. 2023
Keisuke Orimo, Masato Tamari, Tomohiro Takeda, Terufumi Kubo, Beate Rückert, Kenichiro Motomura, Hiroki Sugiyama, Ayako Yamada, Kyoko Saito, Ken Arae, et al. Direct platelet adhesion potentiates group 2 innate lymphoid cell functions. Allergy. 2021. 77. 3. 843-855
Arisa Igarashi, Kenji Matsumoto, Akio Matsuda. MicroRNA-29 suppresses the expression of soluble ST2 and IFNAR1 in human bronchial epithelial cells. Allergy. 2021. 76. 7. 2264-2267
Hirotoshi Unno, Ken Arae, Akira Matsuda, Masashi Ikutani, Masato Tamari, Kenichiro Motomura, Sumika Toyama, Hajime Suto, Ko Okumura, Akio Matsuda, et al. Critical role of IL-33, but not IL-25 or TSLP, in silica crystal-mediated exacerbation of allergic airway eosinophilia. Biochemical and Biophysical Research Communications. 2020. 533. 3. 493-500

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MISC (73)：

Frontiers of Kawasaki disease research. 2021. 35. 2. 145-151
Yohei Nomura, Naoyuki Kimura, Akinori Aomatsu, Akio Matsuda, Yusuke Imamura, Yosuke Taniguchi, Daijiro Hori, Manabu Shiraishi, Kenichi Sakakura, Hiroshi Wada, et al. Transcatheter Aortic Valve Replacement Suppresses Postoperative Immune Responses. CIRCULATION. 2019. 140
松田明生. 基礎から見た衛生仮説の再考. アレルギー. 2019. 68. 1. 29-34
Arisa Igarashi, Akio Matsuda, Kenji Matsumoto. MicroRNA-29 suppresses cytokine-mediated production of soluble IL-33 receptor, sST2, by bronchial epithelial cells. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2018. 141. 2. AB293-AB293
橋本梨沙, 橋本梨沙, 益田博司, 西村奈穂, 小野博, 今留謙一, 阿部淳, 松田明生, 小林徹, 窪田満, et al. PICU管理を要した川崎病症例. 日本川崎病学会学術集会抄録集. 2018. 38th. 87

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Lectures and oral presentations (11)：

培養冠動脈血管内皮細胞のバイオロジーから川崎病の病態メカニズム、新しい治療戦略を考える
(第41回日本川崎病学会学術集会)
Screening for novel drug candidates for treatment of IVIG-resistant Kawasaki disease
基礎研究者から見た臨床と基礎のteam-upの意義と今後の課題
(第67回日本アレルギー学会学術大会 2018)
基礎から見た衛生仮説の再考
(第67回日本アレルギー学会学術大会 2018)
アレルギー疾患の発症機序up-to-date
(第64回日本アレルギー学会学術大会 2015)

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Education (2)：

1991 - 1996 Hokkaido University
1986 - 1990 Tokyo University of Science

Professional career (1)：

PhD(Science) (Hokkaido University)

Work history (8)：

2020/10 - 現在 National Center for Child Health and Development Department of Allergy and Clinical Immunology, Division of Inflammatory Regulation Chief
2017/04 - 2020/09 国立成育医療研究センター研究所
2015/04 - 2017/03 日本医療研究開発機構(AMED) 臨床研究・治験基盤事業部主幹
2012/04 - 2015/03 国立成育医療研究センター研究所
2010/11 - 2012/03 国立成育医療研究センター研究所

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Committee career (4)：

2021/04 - 現在日本川崎病学会運営委員
2017/07 - 2021/06 日本アレルギー学会アレルギー専門医試験問題作成委員
2015/05 - 2021/06 日本アレルギー学会代議員
2016/12 - 2017/03 日本医療研究開発機構 AMEDプログラムオフィサー

Association Membership(s) (7)：

The Japanese Society for Bone and Mineral Reseaech , The Molecular Biology Society of Japan , 日本血管生物医学会 , THE JAPAN SOCIETY FOR CLINICAL IMMUNOLOGY , THE JAPANESE SOCIETY FOR IMMUNOLOGY , 日本川崎病学会 , JAPANESE SOCIETY OF ALLERGOLOGY

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