Rchr
J-GLOBAL ID：200901080968191847   Update date: Oct. 12, 2024

FUJISAWA J.

フジサワ ジユンイチ | FUJISAWA J.
Affiliation and department：
Kansai Medical University

About Kansai Medical University


Job title： Professor
Homepage URL  (1)： http://www3.kmu.ac.jp/microbiol/
Research field  (4)： Virology ,  Cell biology ,  Molecular biology ,  Laboratory animal science
Research theme for competitive and other funds  (41)：
  • 2018 - 2021 Expression and immunogenicity of recombinant vaccinia virus containing the HTLV-1 env gene
  • 2018 - 2020 Role of tumor microenvironment in the chronic infection HTLV-1 and the ATL development
  • 2015 - 2018 根治不能肝腫瘍に対する増殖型遺伝子組換えウイルスを用いた新治療法の臨床応用研究
  • 2015 - 2018 Analysis of factors involved in the establishment of asymptomatic carrier state in HTLV-1 infected humanized mice
  • 2012 - 2015 Efficacy of third-generation oncolytic herpes simplex virus type 1 for advanced hepatocellular carcinoma
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Papers (82)：
  • Takataro Fukuhara, Yoshihiro Ueda, Sung-Il Lee, Tokifumi Odaka, Shinsuke Nakajima, Jun-Ichi Fujisawa, Kazu Okuma, Makoto Naganuma, Kazuichi Okazaki, Naoyuki Kondo, et al. Thymocyte Development of Humanized Mice Is Promoted by Interactions with Human-Derived Antigen Presenting Cells upon Immunization. International Journal of Molecular Sciences. 2023. 24. 14. 11705-11705
  • Koma Takaaki, Odaka Tokifumi, Lee Sung-Il, Doi Naoya, Kondo Tomoyuki, Okuma Kazu, Fujisawa Jun-Ichi, Adachi Akio, Nomaguchi Masako. Humanized mice generated by intra-bone marrow injection of CD133-positive hematopoietic stem cells: application to HIV-1 research. Frontiers in Virology. 2023. 3
  • Atsuhiko Hasegawa, Megumi Murata, Tomoka Fujikawa, Kuniko Katagiri, Yoshiko Nagano, Takao Masuda, Madoka Kuramitsu, Shinsuke Nakajima, Jun-ichi Fujisawa, Kazu Okuma, et al. Vaccination with short-term-cultured autologous PBMCs efficiently activated STLV-1-specific CTLs in naturally STLV-1-infected Japanese monkeys with impaired CTL responses. PLOS Pathogens. 2023. 19. 2. e1011104-e1011104
  • Misaki Matsuo, Takaharu Ueno, Kazuaki Monde, Kenji Sugata, Benjy Jek Yang Tan, Akhinur Rahman, Paola Miyazato, Kyosuke Uchiyama, Saiful Islam, Hiroo Katsuya, et al. Identification and characterization of a novel enhancer in the HTLV-1 proviral genome. Nature Communications. 2022. 13. 1
  • Masateru Hiyoshi, Naofumi Takahashi, Youssef M. Eltalkhawy, Osamu Noyori, Sameh Lotfi, Jutatip Panaampon, Seiji Okada, Yuetsu Tanaka, Takaharu Ueno, Jun-ichi Fujisawa, et al. M-Sec induced by HTLV-1 mediates an efficient viral transmission. PLOS Pathogens. 2021. 17. 11. e1010126-e1010126
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MISC (13)：
  • 水池潤, 山岸誠, 大高時文, 中嶋伸介, 登坂充, 小林誠一郎, 中島誠, 牧山純也, 田中勇悦, 渡邉俊樹, et al. HTLV-1Taxによる標的遺伝子制御機構と感染細胞の遺伝子発現パターン形成. 日本HTLV-1学会学術集会. 2021. 7th
  • 水池潤, 山岸誠, 大高時文, 中嶋伸介, 小林誠一郎, 中島誠, 牧山純也, 田中勇悦, 渡邉俊樹, 鈴木穣, et al. RASGRP3エンハンサーへのHTLV-1 Taxの結合とNF-κB依存的発現誘導. 日本癌学会学術総会抄録集(Web). 2021. 80th
  • 水池潤, 山岸誠, 大高時文, 中嶋伸介, 小林誠一郎, 中島誠, 新谷奈津美, 牧山純也, 宇都宮與, 田中勇悦, et al. Epigenetic MAPK/ERK signaling pathway activation in HTLV-1-infected premalignant model. 日本癌学会学術総会抄録集(Web). 2020. 79th
  • 中嶋伸介, 大高時文, 李成一, 藤澤順一. HTLV-1感染ヒト化マウスにおける感染細胞の表現型解析. 日本HTLV-1学会学術集会. 2019. 6th
  • 大高時文, 中嶋伸介, 李成一, 上野孝治, 任翊華, 姚錦春, 藤澤順一. HTLV-1感染ヒト化マウスリンパ球におけるTaxおよびHBZ mRNAの発現. 日本HTLV-1学会学術集会. 2019. 6th
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Books (3)：
  • 第IV章 ウイルス学・分子生物学 4 HTLV-1のウイルス学「HTLV-1と疾患」
    文光堂 2007 ISBN:9784830614200
  • 「医学書院 医学大辞典」
    医学書院 2003 ISBN:9784260136518
  • 【ウイルス発癌の最前線】 HTLV-1感染細胞腫瘍化におけるウイルス発現抑制機構の関与
    2002
Lectures and oral presentations  (81)：
  • NAD+-poly(ADP-ribose)代謝を標的とした創薬研究の新展開 基礎から臨床応用まで ポリADPリボシル化経路とAKT経路との関連について
    (日本生化学会大会・日本分子生物学会年会合同大会講演要旨集 2015)
  • Altered pattern in viral mRNA expression of Iranian type HTLV-1 leading to enhanced viral expression
    (Retrovirology 2014)
  • ATL-like overgrowth and clonal expansion of HTLV-1 infected CD25+ CD4+ T- lymphocyte in humanized-NOG mouse model
    (Retrovirology 2011)
  • Inverse correlation between Tax and CD25 expressions in HTLV-1 infected CD4 T-cells in vivo
    (Retrovirology 2011)
  • HTLV-1の個体内発現制御における低酸素シグナルの関与
    (第30回日本分子生物学会年会・第80回日本生化学会大会 合同大会 2007)
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Awards (1)：
  • 1990/07 - 日本癌学会 第9回 日本癌学会奨励賞
Association Membership(s) (5)：
The Molecular Biology Society of Japan ,  Japanese Society for Bacteriology ,  The Japanese Cancer Association ,  The Japanese Society for AIDS Research ,  The Japanese Society for Virology
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