Hanashima Shinya

ハナシマシンヤ | Hanashima Shinya

Affiliation and department：
Job title： Professor
Homepage URL (1)： https://sites.google.com/tottori-u.ac.jp/hanashima-lab

Research field (3)： Molecular biochemistry , Bioorganic chemistry , Biophysics

Research keywords (9)： lipid membrane , glycan , fluorescence spectroscopy , Glycolipids , lipids , Organic synthesis , Biomolecular Chemistry , NMR , Natural Products

Research theme for competitive and other funds (12)：

2023 - 2026 Average orientation of lipid acyl chains in the domain structure of model membranes
2023 - 2026 植物特有のスフィンゴ脂質の構造と相互作用が誘起する脂質ラフトの描像の構築
2021 - 2025 Chemical study on dynamics of model lipid bilayers reproducing biomembrane under non-equilibrium conditions
2018 - 2024 高精度1分子観察によるエクソソーム膜動態の解明
2019 - 2022 脂質ラフトにおける糖脂質ータンパク質会合体の形成機序の解明

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Papers (116)：

Tomokazu Yasuda, Daiki Ueura, Madoka Nakagomi, Shinya Hanashima, J. Peter Slotte, Michio Murata. Design, synthesis of ceramide 1-phosphate analogs and their affinity for cytosolic phospholipase A2 as evidenced by surface plasmon resonance. Bioorganic & Medicinal Chemistry Letters. 2024
Michio Murata, Yuichi Umegawa, Shinya Hanashima. NMR Studies on the Structure and Functions of Small Biomolecules with Highly Flexible Conformation. Bulletin of the Chemical Society of Japan. 2023. 96. 10. 1156-1168
Hirofumi Watanabe, Shinya Hanashima, Yo Yano, Tomokazu Yasuda, Michio Murata. Passive Translocation of Phospholipids in Asymmetric Model Membranes: Solid-State 1H NMR Characterization of Flip-Flop Kinetics Using Deuterated Sphingomyelin and Phosphatidylcholine. Langmuir : the ACS journal of surfaces and colloids. 2023. 39. 43. 15153-15408
Shinya Hanashima, Mikito Nakano, Michio Murata. Dynamic assembly and interaction of glycosphingolipids in cholesterol-containing model membranes. Pure and Applied Chemistry. 2023
Joan Candice Ondevilla, Shinya Hanashima, Akane Mukogawa, Darcy Garza Miyazato, Yuichi Umegawa, Michio Murata. Effect of the number of sugar units on the interaction between diosgenyl saponin and membrane lipids. Biochimica et biophysica acta. Biomembranes. 2023. 1865. 5. 184145-184145

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MISC (66)：

花島慎弥, 花島慎弥, 安田智一, 樺山一哉, 廣澤幸一朗, 鈴木健一. Modification of membrane properties of small extracellular vesicle exosomes using lipid exchange. 日本化学会春季年会講演予稿集(Web). 2023. 103rd
YASUDA Tomokazu, HIROSAWA Koichiro M., SUZUKI Kenichi G.N., KABAYAMA Kazuya, MURATA Michio, HANASHIMA Shinya. Elucidation of dynamic behavior of exosome membranes involved in intracellular uptake efficiency. 日本化学会春季年会講演予稿集(Web). 2022. 102nd
渡辺宏史, 花島慎弥, 安田智一, 村田道雄. Leaflet-specific quantification of choline lipids in the two layers of asymmetric vesicles. 日本化学会春季年会講演予稿集(Web). 2022. 102nd
西直也, 安田智一, 花島慎弥, 村田道雄. Dynamic behavior of phosphatidylethanolamine as an inner leaflet lipid in biological model membranes. 日本化学会春季年会講演予稿集(Web). 2022. 102nd
植浦大貴, 中込まどか, 花島慎弥, 安田智一, 安田智一, 村田道雄. Elucidation of dynamic behavior of Ceramide 1-phosphate in lipid bilayers in association with cytosolic phospholipase A₂ activation. 日本化学会春季年会講演予稿集(Web). 2022. 102nd

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Patents (2)：

Lectures and oral presentations (60)：

脂質交換反応を利用した細胞外小胞エクソソームの膜物性改変法
(日本化学会第103春季年会 2023)
ラフト環境でのGM3糖鎖の立体構造ダイナミクス
(第41回日本糖質学会年会 2022)
固体NMR測定による脂質膜環境におけるガングリオシドGM3糖鎖の配座・配向解析
(第41回日本糖質学会年会 2022)
脂質膜近傍のGlycoscience; 糖脂質の脂質膜における構造と相互作用を介した機能の解明を目指して
(第41回日本糖質学会年会 2022)
Conformation of the Ganglioside GM3 Glycan in Lipid Bilayers as Elucidated by Solid-State NMR
(第30回国際糖質会議 ICS2022 2022)

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Education (4)：

2000 - 2003 Tokyo University of Science Graduate School of Science and Technology
1998 - 2000 Tokyo University of Science Graduate School of Science and Technology
1994 - 1998 Tokyo University of Science
- 1994 千葉県立船橋高等学校

Professional career (1)：

Ph.D (Tokyo University of Science)

Work history (7)：

2023/01 - 現在 Tottori University Graduate School of Engineering Chemistry and Biotechnology Biotechnology Professor
2020/10 - 2023/12 Osaka University Graduate School of Science Department of Chemistry Associate Professor
2013/04 - 2020/09 Osaka University Graduate School of Science Department of Chemistry Lecturer
2008/05 - 2013/03 RIKEN Researcher
2007/04 - 2008/04 Kanagawa University Faculty of Engineering, Department of Material and Life C

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Committee career (4)：

2021/07 - 現在 The Japan Society of Carbohydrate Research
2020/01 - 現在 Trends in Glycoscience and Glycotechnology誌編集委員
2019/10 - 現在 FCCA 幹事
2022/10 - 2023/09 日本糖質学会第42回日本糖質学会年会世話人

Awards (2)：

2011/08 - 日本糖質学会日本糖質学会奨励賞
2009/10 - 東京糖鎖研究会 GlycoTokyo 奨励賞

Association Membership(s) (6)：

FCCA , Japan Society for Bioscience, Biotechnology, and Agrochemistry , Japanese Society for Chemical Biology , THE CHEMICAL SOCIETY OF JAPAN , THE NUCLEAR MAGNETIC RESONANCE SOCIETY OF JAPAN , The Japanese Society of Carbohydrate Research

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