Rchr
J-GLOBAL ID：200901081877540098   Update date: Sep. 26, 2024

Mori Kazutoshi

モリ カズトシ | Mori Kazutoshi
Affiliation and department：
Kyoto University Graduate School of Science

About Kyoto University Graduate School of Science


Job title： Professor
Homepage URL  (1)： http://www.upr.biophys.kyoto-u.ac.jp/
Research field  (4)： Pharmacology ,  Pharmaceuticals - health and biochemistry ,  Cell biology ,  Molecular biology
Research keywords  (6)： transcriptional regulation ,  protein ,  organelle ,  cell ,  Signal Transduction ,  情報伝達
Research theme for competitive and other funds  (23)：
  • 2022 - 2025 哺乳動物の小胞体関連分解における小胞体内イベントの全容解明
  • 2017 - 2022 Analysis of sorting zones involved in protein quality control in the endoplasmic reticulum
  • 2017 - 2022 Toward an integrative understanding of functional zones in organelles
  • 2017 - 2020 Analysis of recognition mechanisms of misfoled proteins accumulated in the endoplasmic reticulum
  • 2014 - 2017 Elucidation of regulation mechanism of the endoplasmic reticulum membrane-bound transcription factor ATF6 and its role in the evolution of vertebrates
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Papers (135)：
  • Satoshi Ninagawa, Masaki Matsuo, Deng Ying, Shinya Aso, Kazutoshi Matsushita, Akane Fueki, Shunsuke Saito, Koshi Imami, Yasuhiko Kizuka, Tetsushi Sakuma, et al. UGGT1/2-mediated reglucosylation ofN-glycan competes with ER-associated degradation of unstable and misfolded glycoproteins. 2023
  • Tomoyo Ikeda, Tokiro Ishikawa, Satoshi Ninagawa, Tetsuya Okada, Masaya Ono, Kazutoshi Mori. Proteomic analysis of fatty liver induced by starvation of medaka fish larvae. Cell structure and function. 2023. 48. 2. 123-133
  • Byungseok Jin, Tokiro Ishikawa, Makoto Kashima, Rei Komura, Hiromi Hirata, Tetsuya Okada, Kazutoshi Mori. Activation of XBP1 but not ATF6α rescues heart failure induced by persistent ER stress in medaka fish. Life Science Alliance. 2023. 6. 7. e202201771-e202201771
  • Takashi Tanaka, Dinh Thi Nguyen, Nichakarn Kwankaew, Megumi Sumizono, Reika Shinoda, Hiroshi Ishii, Mika Takarada-Iemata, Tsuyoshi Hattori, Seiichi Oyadomari, Nobuo Kato, et al. ATF6β Deficiency Elicits Anxiety-like Behavior and Hyperactivity Under Stress Conditions. Neurochemical Research. 2023
  • Shengyu Jin, Byungseok Jin, Tokiro Ishikawa, Satoshi Ninagawa, Tetsuya Okada, Sho Koyasu, Hiroshi Harada, Kazutoshi Mori. Loss of ATF6α in a Human Carcinoma Cell Line Is Compensated not by Its Paralogue ATF6β but by Sustained Activation of the IRE1 and PERK Arms for Tumor Growth in Nude Mice. Molecular Biology of the Cell. 2023
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MISC (50)：
  • 蜷川暁, 蜷川暁, 松尾將生, DENG Ying, 森和俊. Folding or Degradation, Molecular Mechanisms Determining the Fate of Glycoproteins in the Endoplasmic Reticulum. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
  • 蜷川暁, 森和俊. 小胞体における構造不全糖タンパク質の代謝タイミング決定の分子機構. 日本生化学会大会(Web). 2023. 96th
  • 蜷川暁, 蜷川暁, 松尾將生, DENG Ying, 阿曽伸哉, 松下和俊, 笛木茜, 斎藤俊介, 今見考志, 木塚康彦, et al. UGGTs prevent premature degradation of unstable and misfolded glycoproteins in the endoplasmic reticulum. 日本糖質学会年会要旨集. 2023. 42nd
  • 松尾將生, DENG Ying, 矢木宏和, 矢木宏和, 津曲和哉, 笛木茜, 今見考志, 加藤晃一, 加藤晃一, 加藤晃一, et al. UGGTs affect not only glycoprotein folding but also degradation. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
  • 蜷川暁, 蜷川暁, 森和俊. Elucidating mechanisms underlying the robustness of the newly synthesized protein load in the endoplasmic reticulum. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
ｍore...
Books (1)：
  • Molecular Biology inside the Cell
    Kodansha-bluebacks 2016
Education (4)：
  • - 1983 Kyoto University
  • - 1983 Kyoto University Graduate School, Division of Pharmaceutical Sciences
  • - 1981 Kyoto University Faculty of Pharmaceutical Sciences
  • - 1981 Kyoto University Faculty of Pharmaceutical Science
Professional career (1)：
  • Doctor of Pharmaceutical Science
Work history (7)：
  • 2003/11/01 - Graduate School of Science, Kyoto University Peofessor
  • 1999/04/01 - Graduate School of Biostudies, Kyoto University Associate Professor
  • 1996/04/01 - HSP Research Institute Research Manager
  • 1993/10/01 - HSP Research Institute Deputy Research Manager
  • 1989/04/01 - University of Texas Southwestern Medical Center at Dallas Postdoctoral Fellow
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Awards (22)：
  • 2019/03 - 安藤百福賞大賞
  • 2018/11 - 文化功労者
  • 2017/12 - ブレークスルー賞生命科学分野
  • 2017/08 - 岡山県三木記念賞を
  • 2017/04 - 日本内分泌学会マイスター賞
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Association Membership(s) (7)：
日本細胞生物学会 ,  日本分子生物学会 ,  日本生化学会 ,  The American Society for Cell Biology ,  American Society for Biochemistry and Molecular Biology ,  The Japanese Society for Genome Editing ,  The Biomedical Society for Stress Response
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