YASUHARA Noriko

ヤスハラノリコ | YASUHARA Noriko

Affiliation and department：
Job title： Professor

Research field (2)： Developmental biology , Cell biology

Research keywords (8)： importinα , 核-細胞質間分子輸送 , 情報伝達制御 , 初期胚発生 , 細胞分化 , imortin α , 胚発生 , 核-細胞質間蛋白質輸送

Research theme for competitive and other funds (10)：

2021 - 2025 核輸送因子による新たなDNAターゲッティング機構の解明
2018 - 2020 核輸送因子局在化ゾーンによる細胞核内外オルガネラ連携
2015 - 2018 The role of the nucleocytoplasmic transport during embryogenesis
2013 - 2018 Mechanisms of nuclear transport factor/nucleoporin-mediated chromatin regulation
2014 - 2017 Control of transcription factors and epigenetic factors via nuclear transport and its application to targeted therapy

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Papers (26)：

Rashid Mehmood, Alanoud Alsaleh, Muzamil Y. Want, Ijaz Ahmad, Sami Siraj, Muhammad Ishtiaq, Faizah A. Alshehri, Muhammad Naseem, Noriko Yasuhara. Integrative Molecular Analysis of DNA Methylation Dynamics Unveils Molecules with Prognostic Potential in Breast Cancer. BioMedInformatics. 2023. 3. 2. 434-445
Kazuya Jibiki, Takashi S. Kodama, Noriko Yasuhara. Importin alpha family NAAT/IBB domain: Functions of a pleiotropic long chameleon sequence. Advances in Protein Chemistry and Structural Biology. 2023. 134. 175-209
Rashid Mehmood, Kazuya Jibiki, Zakeya J. Alsafwani, Muhammad Naseem, Noriko Yasuhara. Systems genomics of nucleoporins provides prognostic insights into breast cancer. Advancements in Life Science. 2022. 9. 1. 98-110
Kazuya Jibiki, Mo-yan Liu, Chao-sen Lei, Takashi S. Kodama, Chojiro Kojima, Toshimichi Fujiwara, Noriko Yasuhara. Biochemical propensity mapping for structural and functional anatomy of importin α IBB domain. Genes to Cells. 2021. 27. 3. 173-191
Kazuya Jibiki, Takashi S. Kodama, Atsushi Suenaga, Yota Kawase, Noriko Shibazaki, Shin Nomoto, Seiya Nagasawa, Misaki Nagashima, Shieri Shimodan, Renan Kikuchi, et al. Importin α2 association with chromatin: Direct DNA binding via a novel DNA-binding domain. Genes to Cells. 2021. 26. 12. 945-966

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MISC (5)：

Books (1)：

Regulation of Downstream Targets - Advances in Protein Chemistry and Structural Biology, Volume 134
Academic Press, an imprint of Elsevier 2023 ISBN:9780443131813

Lectures and oral presentations (7)：

Importin α proteins differentially localize in cytoplasm
(MBSJ2020 2020)
A nuclear transport receptor importin α2 associates with chromatin via novel DNA binding domain, NAAT
(MBSJ2020 2020)
新規ドメインを介した核輸送因子importinαのDNA結合様式解析
(第93回日本生化学会大会 2020)
核輸送因子importin αのクロマチン結合解析
(第72回日本細胞生物学会大会 2020)
核輸送因子importin α2はDNAとの結合を介して遺伝子の発現に関わる
(第42回日本分子生物学会年会 2019)

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Work history (4)：

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