Novel approach: Elucidating the intracellular clearance mechanism of toxic AGEs (TAGE) utilizing the artificial. CHK1 mutant d270KD as a substrate model.
(2023)
The HECT-type ubiquitin ligase Mule is involved in the kinase-inactive mutation-specific rapid degradation of Chk1 lacking its carboxyl terminus.
(The 43rd Annual Meeting of the Molecular Biology Society of Japan 2020)