Matsuo Muneaki

マツオムネアキ | Matsuo Muneaki

Affiliation and department：
Job title： Professor

Research field (1)： Fetal medicine/Pediatrics

Research keywords (2)：小児科学 , Pediatrics

Research theme for competitive and other funds (23)：

2024 - 2029 Environmental factors under autophagy regulation causing the development of Hutchinson-Gilford progeria syndrome
2024 - 2027 iPS細胞を用いた反復性急性肝不全(RALF)の病態解明
2023 - 2026 Kleine-Levin症候群の実態調査及び病態解明に関する研究
2023 - 2026 Basic and clinical research to elucidate the pathophysiological feature of Niemann Pick disease type C for creating next-generation treatments
2023 - 2026 神経皮膚症候群および色素性乾皮症・ポルフィリン症の学際的診療体制に基づく医療最適化と患者 QOL 向上のための研究

2022 - 2025 小児有熱性けいれん重積のなかでのけいれん重積型急性脳症発症予測

2023 - 2025 新・標的分子と新・神経機能解析法を用いた糖脂質代謝異常症の薬剤開発

2021 - 2024 Nationwide study to improve the quality of medical care and patient QOL through the accumulation of evidence on progeroid syndromes

2021 - 2023 新技術と新治療コンセプトに基づく先天代謝異常症に対する治療薬開発

2017 - 2021 Development of ICT-based nursing education programs for long-term home support for children and families

2017 - 2020 Establishment of lipid carrier therapy using cyclodextrin derivatives against Niemann-Pick disease type C

2016 - 2019 Study for the pathogenesis of moyamoya disease from aspect of vascular shear stress and endothelium

2014 - 2017 Translational research on the effects of intracerebroventricular administration of 2-hydroxypropyl-beta-cyclodextrin against Niemann-Pick disease type C

2013 - 2016 Study for pathogenesis of Moyamoya disease using induced pluripotent stem cells

2011 - 2013 Cyclodextrins as Modifiers of Intracellular Cholesterol Trafficking in Niemann-Pick Disease Type C

2003 - 2004 INF-α productivity and Toll-like receptor 3 gene polymorphism in patients with febrile seizure

2002 - 2004 Regulatory mechanisms of leukotrene(LT) synthesizing and degrading enzymes, and LT receptos

1998 - 1999 脳腫瘍の増殖におけるプロスタグランディンの関与とその機序

熱性けいれんの発症機序

中枢神経のリピッドメディエーター

小児神経学に関する研究

Lipid mediators in central nervus system

Study on Pediatric Neurology

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Papers (115)：

Yusei Yamada, Yoichi Ishitsuka, Madoka Fukaura-Nishizawa, Tatsuya Kawata, Akira Ishii, Aina Shirakawa, Taichi Sakai, Mayuko Tanaka, Yuki Kondo, Toru Takeo, et al. Intracerebroventricular 2-hydroxypropyl-γ-cyclodextrin alleviates hepatic manifestations without distributing to the liver in a murine model of Niemann-Pick disease type C. Life Sciences. 2024. 350. 122776-122776
Muneaki Matsuo, Takafumi Sakakibara, Yoshio Sakiyama, Tetsumin So, Motomichi Kosuga, Toshihiko Kakiuchi, Fumio Ichinose, Takuji Nakamura, Yoichi Ishitsuka, Tetsumi Irie. Long-term efficacy of intrathecal cyclodextrin in patients with Niemann-Pick disease type C. Brain & development. 2024. 46. 5. 207-212
Kinuka Doi, Rintaro Sogawa, Yuko Eguchi, Muneaki Matsuo, Chisato Shimanoe. Association between Early Guanfacine Discontinuation and Somnolence for Attention-Deficit/Hyperactivity Disorder. Biological & pharmaceutical bulletin. 2024. 47. 6. 1204-1208
Maika Kudoh, Toshihiko Kakiuchi, Masato Yoshiura, Motohiro Esaki, Muneaki Matsuo. Fecal calprotectin measurement to detect recurrence of solitary juvenile polyps: A case report. Medicine. 2023. 102. 43. e35448
Toshihiko Kakiuchi, Muneaki Matsuo, Hiroyoshi Endo, Yasuhisa Sakata, Motohiro Esaki, Takahiro Noda, Ichiro Imamura, Kazutoshi Hashiguchi, Shinichi Ogata, Yasuhiko Fujioka, et al. Efficacy and safety of vonoprazan-based regimen for Helicobacter pylori eradication therapy in Japanese adolescents: a prospective multicenter study. Journal of gastroenterology. 2023. 58. 3. 196-204

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MISC (69)：

Yoichi Ishitsuka, Tetsumi Irie, Muneaki Matsuo. Cyclodextrins applied to the treatment of lysosomal storage disorders. Advanced Drug Delivery Reviews. 2022. 191
石井亮良, 片山莉乃, 近藤悠希, 山田侑世, 山田侑世, 東大志, 本山敬一, 有馬英俊, 檜垣克美, 松尾宗明, et al. Niemann-Pick病C型治療薬候補としての2-hydroxypropyl-β-cyclodextrinの有効性と安全性に対する置換度の影響. 日本薬学会九州支部大会講演要旨集. 2021. 38th
井原健二, 松尾宗明, 小崎里華. 早老症の医療水準やQOL向上を目指す集学的研究ハッチンソン・ギルフォード症候群:指定難病の承認に向けた取り組みとプロジェリアハンドブック改訂2版日本語版の作成. 早老症の医療水準やQOL向上を目指す集学的研究令和元年度総括・分担研究報告書(Web). 2020
前田寿幸, 樋口直弥, 峰松伸弥, 一ノ瀬文男, 宇田恵子, 岩永学, 松尾宗明, 古賀靖敏, 村山圭. 生下時より著明な筋緊張・筋力低下を認め,経過中に血球貪食症候群を呈した新生児/乳児ミトコンドリア病の3か月男児例. 脳と発達. 2019. 51. 1. 41
中山愛子, 垣内俊彦, 松尾宗明. タクロリムスで寛解維持できず、インフリキシマブにスイッチした難治性潰瘍性大腸炎の小児例. 小児科臨床. 2018. 71. 9. 1525-1530

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Education (2)：

- 1985 Saga Medical School
- 1985 Saga Medical School Faculty of Medicine

Professional career (1)：

(BLANK)

Work history (1)：

2014/12 - 現在 Saga University Faculty of Medicine, Department of Pediatrics Professor

Association Membership(s) (2)：

日本小児神経学会 , 日本小児科学会

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