Rchr
J-GLOBAL ID：200901086123806336
Update date: Jan. 31, 2024
Kashiwagi Kenji
カシワギ ケンジ | Kashiwagi Kenji
Affiliation and department：
Job title：
Professor
Research field (1)：
Ophthalmology
Research keywords (7)：
glaucoma drug therapy screening medical supporting system
, 緑内障 薬物治療 スクリーニング 診療支援システム
, Mechanisum of glaucoma medicine; culture of retinal ganglion cells
, 網膜神経節細胞培養
, 緑内障薬物治療のメカニズム
, 眼科学
, ophthalmology
Research theme for competitive and other funds (31)：
- 2022 - 2027 AIR-Glasses:AI-ARを用いた視知覚ベース個別適応型色覚情報補償技術
- 2022 - 2025 Investigation of the onset and progression mechanisms of primary open-angle glaucoma - Association between the genetic variants associated with primary open-angle glaucoma and visual field loss -
- 2021 - 2024 Mechanisms underlying retinal glia-mediated glaucoma
- 2020 - 2024 加齢黄斑変性患者の視界を改善するコレクト/コンプリメント・リアリティ(CR)技術
- 2020 - 2023 山梨県域をバーチャル診療機関とした緑内障プレシジョンメディシンの推進
- 2017 - 2022 Computational Ophthalmology: Adaptive Vision Enhancement for the Visually Impaired using Augment Reality
- 2018 - 2021 Investigation of the onset and progression mechanisms of primary open-angle glaucoma -Involvement of genetic variants associated with primary open-angle glaucoma in phenotypic features-
- 2017 - 2020 Development of bio-nanosheet for newly ophthalmic treatment devices
- 2015 - 2018 Investigation of the onset mechanism of primary open-angle glaucoma -Genetic investigation of the mechanism of intraocular pressure elevation-
- 2014 - 2017 Development of new drug delivery systems in ophthalmology using bionanosheet
- 2013 - 2016 Study on Developing Regional-Sharing of Drug-Administrating Information as a Purpose of Realizing "DOKODEMO MY-BYOUIN (My Hospital Anywhere)" Plan
- 2012 - 2015 Investigation of the mechanisms of intraocular pressure regulation (elevation) by estrogen-receptor
- 2011 - 2012 Elucidation of cause of glaucoma by a MAN-network analysis
- 2009 - 2011 Investigation of susceptibility genes for primary open-angle glaucoma-Analysis of ESR2 gene polymorphisms-
- 2009 - 2011 Investigation of role of glial cells in glaucomatous optic neuropathy and searching glial cell-related treatment for glaucoma
- 2007 - 2008 Research for mechanisms and treatments of glaucomatous axonal flow damage
- 2006 - 2008 Damage of retinal ganglion cells : Mechanism of the cell death in the local and central nervous system and protection and regeneration of the neural cells.
- 2005 - 2006 Comprehensive and prompt basic science study for protecting retinal ganglion cell by combined system of cultured cell and individual animals and application for clinical approach
- 2003 - 2004 Investigation for mechanism and protection of retinal ganglion cell death using several culture disease-model systems
- 2002 - 2004 Basic and practical investigations on neuro-protective or regenerative treatments of retinal neuropathic ocular
- 2000 - 2001 Research about etiology and prophylactic program in open angle glaucoma
- 1999 - 2001 Development of readily applicable glaucoma new drugs for lowering intraocular pressure, improvement of ocular circulation, and neuronprotection
- 1999 - 2000 プロスタグランデイン点眼薬の眼圧下降機序と神経保護作用に関する影響の研究
- 1998 - 2000 Todevelopea handy home-use tonometry
- 1997 - 1998 プロスタグランジン製剤点眼薬の眼圧降下機序解明に関する研究
- Glaucoma,Regional medical coaliation
- 緑内障、地域医療連携
- survival associated factors of retnal neuron cell
- Development of screening system for angle-closure glaucoma
- survival associated factors of refiral neuron cell
- The mechanism of IOP reduction by prostoglandins
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Papers (77)：
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Fumihiko Mabuchi, Nakako Mabuchi, Yoichi Sakurada, Seigo Yoneyama, Kenji Kashiwagi, Zentaro Yamagata, Mitsuko Takamoto, Makoto Aihara, Takeshi Iwata, Kazuki Hashimoto, et al. Genetic variants associated with glaucomatous visual field loss in primary open-angle glaucoma. Scientific reports. 2022. 12. 1. 20744-20744
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Yang Pan, Akiko Suga, Itaru Kimura, Chojiro Kimura, Yuriko Minegishi, Mao Nakayama, Kazutoshi Yoshitake, Daisuke Iejima, Naoko Minematsu, Megumi Yamamoto, et al. METTL23 mutation alters histone H3R17 methylation in normal-tension glaucoma. The Journal of clinical investigation. 2022. 132. 21
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柏木 賢治, 豊浦 正広, 茅 暁陽, 川瀬 和秀, 谷戸 正樹, 中澤 徹, 三木 篤也, 森 和彦, 吉冨 健志. 医師による緑内障判定に対する人工知能の影響. 日本眼科学会雑誌. 2022. 126. 臨増. 177-177
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福田 佳子, 柏木 賢治, 豊浦 正広, 茅 暁陽, 村尾 晃平, 佐藤 真一, 二宮 洋一郎, 川瀬 和秀, 谷戸 正樹, 中澤 徹, et al. 眼底写真による緑内障重症度判定能の医師と人工知能の比較. 日本眼科学会雑誌. 2022. 126. 臨増. 178-178
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Kentaro Hamada, Youichi Shinozaki, Kazuhiko Namekata, Mami Matsumoto, Nobuhiko Ohno, Takahiro Segawa, Kenji Kashiwagi, Takayuki Harada, Schuichi Koizumi. Loss of P2Y 1 receptors triggers glaucoma-like pathology in mice. British Journal of Pharmacology. 2021
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MISC (231)：
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HAMADA Kentaro, SHINOZAKI Yoichi, SHINOZAKI Yoichi, NAMEKATA Kazuhiko, OHNO Nobuhiko, OHNO Nobuhiko, SEGAWA Takahiko, HARADA Takayuki, KASHIWAGI Kenji, KOIZUMI Shuichi, et al. P2Y1 receptor is a novel target for anti-glaucoma treatment. 日本薬理学会年会(Web). 2021. 94th
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篠崎陽一, 篠崎陽一, 行方和彦, 柏木賢治, 大野伸彦, 大野伸彦, 繁冨英治, 繁冨英治, 原田高幸, 小泉修一, et al. Astrocytes trigger early remodeling of optic nerve head in NTG model mouse. 日本眼科学会雑誌. 2021. 125
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濱田健太郎, 篠崎陽一, 篠崎陽一, 行方和彦, 大野伸彦, 大野伸彦, 原田高幸, 柏木賢治, 小泉修一, 小泉修一. P2Y1 receptor loss causes ocular hypertension and loss of retinal ganglion cells. 日本眼科学会雑誌. 2021. 125
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HAMADA Kentaro, SHINOZAKI Youichi, SEGAWA Takahiro, NAMEKATA Kazuhiko, OHNO Nobuhiko, OHNO Nobuhiko, HARADA Takayuki, KASHIWAGI Kenji, KOIZUMI Schuichi. Loss of P2Y1 receptor causes ocular hypertension and glaucoma-like phenotype in mice. 日本薬理学会年会(Web). 2020. 93rd
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HAMADA Kentaro, SHINOZAKI Yoichi, SHINOZAKI Yoichi, NAMEKATA Kazuhiko, OHNO Nobuhiko, OHNO Nobuhiko, SEGAWA Takahiro, HARADA Takayuki, KASHIWAGI Kenji, KOIZUMI Schuichi, et al. Hypertensive glaucoma is induced by impairment of P2Y1 receptor function. 日本神経化学会大会抄録集(Web). 2020. 63rd
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Patents (3)：
Books (25)：
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閉塞隅角とその類縁状態 見落としやすい間欠的な閉塞隅角
メディカルビュー社 2008
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瞳孔ブロック
金原出版(株) 2008
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PRACTICE
医歯薬出版株式会社 2008
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手術手技 コツと落とし穴/強角膜ブロック切除 無硝子体・無水晶体眼での注意と対処
メディカルビュー社 2008
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術後管理 低眼圧黄斑症のメカニズムと対処索
メディカルビュー社 2008
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Lectures and oral presentations (310)：
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眼科遠隔診療ロボットと細隙灯顕微鏡による緑内障術後評価の一致性
(第20回日本緑内障学会 2009)
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Reverse pupillary blockが原因と思われた中心前房深度が深い閉塞隅角緑内障眼の1例
(第20回日本緑内障学会 2009)
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塩酸ロメリジン内服の緑内障性視野障害進行に対する影響
(第20回日本緑内障学会 2009)
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緑内障患者における心気-うつ傾向に関与する因子についての検討
(第20回日本緑内障学会 2009)
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前眼部OCT(CASIA)と走査型周辺前房深度計(SPAC)の測定結果の比較
(第20回日本緑内障学会 2009)
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Education (2)：
- - 1986 山梨医科大学
- - 1986 Yamanashi Medical University Faculty of Medicine
Professional career (2)：
Work history (5)：
- 2019/11 - 現在 University of Yamanashi Ophthalmology Professor
- 2008/04 - University of Yamanashi Graduate Faculty of Interdisciplinary Research Faculty of Education, Education (Childhood developmental education)
- 2002/10 - University of Yamanashi Human Science (Science education), Graduate Faculty of Interdisciplinary Research Faculty of Education
- 1997/05 - 山梨医科大学講師(眼科学)
- 1994/01 - 山梨医科大学助手(眼科学)
Committee career (11)：
- 2020/05 - 現在 日本眼科AI学会 理事
- 2007/04 - 2011/03 日本緑内障学会 評議員
- 2007/12 - 2010/01 The Open Journal of Ophthalmology Editorial board member
- 2007/10 - 2009/09 World Glaucoma Association Associated advisory board member
- 2009/06 - 日本遠隔医療学会 理事
- 2007/06 - 2009/05 The International Glaucoma Review Editorial board member
- 2007/04 - 2009/03 日本眼科学会 評議員
- 2005/04 - 2008/03 Association of International Glaucoma Societies Associate Advisory board member
- 2007/04 - 日本眼薬理学会 評議員
- Journal of Glaucoma Editorial board member
- Journal of Current Glaucoma Proctice Editorial board member
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Awards (7)：
Association Membership(s) (7)：
American Academy of ophthalmology
, The Association for research in vison and ophthalmology
, 日本遠隔医療学会
, 日本眼薬理学会
, 日本緑内障学会
, 日本眼科学会
, 日本手術学会
