- 2024 - 2028 Elucidation of mechanisms underlying immunosenescence resilience by NALT denritic cells-targeting mucosal adjuvant
- 2022 - 2025 舌下免疫で誘導される制御性T細胞の組織間移動によるI型アレルギー抑制機序の解明
- 2022 - 2025 高齢者気道組織を再現する動物モデルを用いた肺炎発症機構の解明と診断法への応用
- 2022 - 2023 新型コロナウイルス(SARS-CoV-2 )表面タンパク抗原に対する新規粘膜アジュバントの免 疫応答性の検証
- 2020 - 2023 Rejuvenation of mucosal immunosenescence by the sublingual vaccine: The prevention and treatment for periodontal disease and arteriosclerosis
- 2020 - 2023 Dynamic in vivo fluorescence imaging analysis of Immunocytes relevant to salivary IgA production.
- 2019 - 2022 Verification of inhibitory effect of atherogenesis on arteriosclerosis with a novel nasal adjuvant.
- 2018 - 2022 ストレス誘導性老化細胞の挙動解析から迫る未知なる骨形成阻害機構の解明
- 2018 - 2021 舌下粘膜組織に存在する免疫細胞クラスターの口腔免疫応答における役割の解明
- 2017 - 2020 Verification of the inhibitive capacity by the salivary protein derived-peptide specific secretory IgA antibody on periodontal disease-pathogenic bacteria colonization.
- 2017 - 2020 Elucidation of the terminal differentiation mechanism of IgA plasma cells on murine salivary glands and the influence of aging on the mechanism.
- 2011 - 2013 生物多様性を保つヒト唾液タンパク質由来能動・受動免疫型歯周病予防ワクチンの開発
- 2010 - 2011 The oral immunological effect on bisphosphonate-treated mice model by periodontal disease associated-pathogen
- 2007 - 2011 歯周病による動脈硬化,糖尿病,低体重児出産の誘発機序の解明とその制御
- 2010 - 2010 [フィージビリティスタディ(探索タイプ)]
- 2008 - 2010 Role of multifunctional protein, GAPDH, associated with bacteria and human cells in infection by periodontopathic bacteria
- 2009 - 2009 平成21年度「シーズ発掘試験」A(発掘型)
- 2007 - 2009 Molecular mechanism involved in the association of periodontal disease with pathology of metabolic syndrome
- 2007 - 2009 胸腺非依存性抗原特異的IgA抗体誘導のための自然免疫賦活化メカニズムの解明
- 2008 - 2008 粘膜免疫学を基盤とした粘膜ワクチン開発および粘膜免疫システムの解明
- 2006 - 2008 Search for inhibitory structures against adhesions of bacteria : construction and application of designed peptide libraries intended for prevention of infective endoearditis
- 2006 - 2007 金属結合ヒト唾液タンパク質の経口投与による金属アレルギー発症動物モデルの作製
- 2006 - 2007 Identification of Streptoooocus gordoniigenes involved in recruiting Porphyromonas gingivatiscens into a multispecies biofilm
- 2006 - 2007 Elucidation of molecular mechanism on periodontal bacterial adherence, invasion and signal transduction to human cell
- 2005 - 2006 Elucidation of molecular mechanism of binding between periodontopathic bacteria and oral streptococci, and development of agents which inhibit forming of dental biofilm
- 2005 - 2006 T細胞非依存性抗原特異的唾液IgA産生における経鼻アジュバントの機能解明
- 2001 - 2003 老人性肺炎に関与する口腔細菌の定着を阻害するペプチドの開発
- 1999 - 2001 Biomolecular analysis on iron acquisition mechanism and pathogenicity of periodontopathic bacteria
- 1999 - 2001 歯周病原性菌の定着を促す唾液タンパク質を導入した歯周病惹起動物モデルの作製
- 1997 - 1999 歯周病原性菌のペリクルへの付着を阻害するペプチドの連鎖球菌への遺伝子導入と発現
- 1997 - 1998 Development of inhibitory peptide in adherence of periodontopathic bacteria to dental plaqu
- 1996 - 1997 Analysis of structure and function of saliva protein receptor domains for periodontopathogen
- 1996 - 1996 ポルフィロモナスジンジバリスのヘモグロビン結合性蛋白質の精製と遺伝子クローニング
- 1995 - 1996 Mechanism of Periodontal Destruction in Gingival Microcirculation by Cigarette Smoking
- Adjuvant in Mucosal Immunology
- Mucosal Immunology
- Study on the periodontopathogenic bacterial adherence to salivaryprotein
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四国歯学会
, 国際粘膜免疫学会
, アメリカ免疫学会(AAI)
, 日本免疫学会
, IADR
, JADR
, 日本歯周病学会
, 日本口腔衛生学会
, AAP
, THE JAPANESE BIOCHEMICAL SOCIETY
, JAPANESE SOCIETY OF PUBLIC HEALTH
, JAPANESE DENTAL EDUCATION ASSOCIATION
, JAPANESE ASSOCIATION FOR ORAL BIOLOGY
