Rchr
J-GLOBAL ID：200901086471955574   Update date: Jun. 18, 2024

Sasakawa Chihiro

ササカワ チヒロ | Sasakawa Chihiro
Affiliation and department：
Chiba University Medical Mycology Research Cdenter

About Chiba University Medical Mycology Research Cdenter


Job title： director
Homepage URL  (1)： http://www.ims.u-tokyo.ac.jp/bac/h.p./mainpage.html
Research field  (3)： Immunology ,  Bacteriology ,  Molecular biology
Research keywords  (8)： immunology ,  infection biology ,  Cellular Microbiology ,  Bacterial Infectious Disease ,  Bacterial Pathogenesis ,  細胞微生物学 ,  細菌感染症 ,  病原細菌学
Research theme for competitive and other funds  (47)：
  • 2012 - 2017 Generalization of harmonized supramolecular motility machinery and its diversity
  • 2011 - 2015 Study of bacterial stratagem to circumvent host innate immune system and its application.
  • 2008 - 2011 Study of Shigella infectious strategy for the intestinal barrier
  • 2006 - 2011 Matrix of Infection Phenomena
  • 2006 - 2010 Support for Research Techniques and Materials
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Papers (104)：
  • Ryota Otsubo, Hitomi Mimuro, Hiroshi Ashida, Jun Hamazaki, Shigeo Murata, Chihiro Sasakawa. Shigella effector IpaH4.5 targets 19S regulatory particle subunit RPN13 in the 26S proteasome to dampen cytotoxic T lymphocyte activation. Cellular Microbiology. 2019. 21. 3. e12974
  • Shiho Suzuki, Toshihiko Suzuki, Chihiro Sasakawa. IAP family members are involved in inflammasome activation in response to bacterial infection. Japanese Journal of Bacteriology. 2018. 73. 1. 130-130
  • Suzuki S, Suzuki T, Mimuro H, Mizushima T, Sasakawa C. Shigella hijacks the glomulin-cIAPs-inflammasome axis to promote inflammation. EMBO reports. 2018. 19. 1. 89-101
  • Ryu Jinhyeob, 大坪 亮太, 飯田 真珠子, 芦田 浩, 笹川 千尋, 三室 仁美. 宿主ユビキチンE3リガーゼによる腸管病原性大腸菌の病原性抑制作用(Host E3 ubiquitin ligase limits pathogenicity of Enteropathogenic E. coli). 日本細菌学雑誌. 2017. 72. 1. 60-60
  • Kenji Takagi, Minsoo Kim, Chihiro Sasakawa, Tsunehiro Mizushima. Crystal structure of the substrate-recognition domain of the Shigella E3 ligase IpaH9.8. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS. 2016. 72. Pt 4. 269-275
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MISC (63)：
  • 鈴木 志穂, 鈴木 敏彦, 三室 仁美, 笹川 千尋. GLMNは細菌感染におけるinflammasome活性化のnegative regulatorである. 日本細菌学雑誌. 2016. 71. 1. 94-94
  • 鈴木 志穂, 三室 仁美, 小川 道永, 芦田 浩, 鈴木 仁人, 真田 貴人, 笹川 千尋. 赤痢菌IpaH7.8 E3ユビキチンリガーゼはglomulinを標的化して炎症を活性化する(Shigella IpaH7.8 E3 ubiquitin ligase targets glomulin to activate inflammasomes). 日本細菌学雑誌. 2015. 70. 1. 217-217
  • Hiroshi Ashida, Minsoo Kim, Chihiro Sasakawa. Manipulation of the host cell death pathway by Shigella. CELLULAR MICROBIOLOGY. 2014. 16. 12. 1757-1766
  • Aaron Irving, Hitomi Mimuro, Thomas Kufer, Camden Lo, Lorinda Turner, Belinda Thomas, John Bertin, Ivo Boneca, Chihiro Sasakawa, Dana Philpott, et al. Identification of the intracellular location and mechanisms of NOD1-dependent inflammatory responses. CYTOKINE. 2014. 70. 1. 50-50
  • 鈴木 志穂, Franchi Luigi, He Yuan, Munoz-Planillo Raul, 三室 仁美, 鈴木 敏彦, 笹川 千尋, Nunez Gabriel. Naip2は赤痢菌MxiIを認識しNlrc4 Inflammasomeを活性化する(Shigella Mxil is recognized by Naip2 to induce Nlrc4 inflammasome activation). 日本細菌学雑誌. 2014. 69. 1. 164-164
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Books (2)：
  • 医科細菌学(編集)改訂第3版
    南江堂 2001
  • 赤痢菌の宿主細胞侵入・拡散とその発現調節(分担執筆)
    菜根出版,医学微生物学の新しい展開 1993
Education (3)：
  • 1974 - 1978 The University of Tokyo Graduate School of Medicine
  • 1972 - 1974 Chiba University Graduate School of Pharmaceutical Sciences
  • 1968 - 1972 Chiba University Faculty of Science
Professional career (2)：
  • (BLANK) (The University of Tokyo)
  • (BLANK) (Chiba University)
Work history (9)：
  • 2013/04 - 現在 Chiba University Research Center for Pathogenic Fungi and Microbial Toxicoses diector
  • 1998 - 2001 Osaka University Research Institute for Microbial Diseases Adjunct Professor
  • 1986 - 1995 The University of Tokyo
  • 1986 - 1995 University of Tokyo, Assistant Professor
  • 1995 - - 東京大学 教授
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Committee career (4)：
  • 2016 - 2023 American Society for Microbiology American Academy of Microbiology
  • 2011 - 2017 Science Council of Japan Member
  • 2012 - 2015 Federation of Microbiological Society of Japan Chaiman
  • 2006 - 2008 Japanese Society for Bacteriology Director
Awards (7)：
  • 2021 - 内閣府 瑞宝中綬章
  • 2012 - Medal with Purple Ribbon
  • 2012 - Japanese Society for Bacteriology Asakawa Award
  • 2006 - Takeda Science Foundation The Takeda Prize for Medical Science
  • 1998 - 野口英世記念医学賞
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Association Membership(s) (5)：
日本免疫学会 ,  米国微生物学会 ,  日本分子生物学会 ,  日本細菌学会 ,  日本獣医学会
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