INAGAKI-OHARA Kyoko

イナガキキョウコ | INAGAKI-OHARA Kyoko

Affiliation and department：
Job title： Professor

Research field (1)： Immunology

Research keywords (2)：消化管免疫、がん、肥満、炎症 , Mucosal Immunology

Research theme for competitive and other funds (12)：

2022 - 2025 Regulatory mechanisms of gastric cancer based on leptin signaling in mice
2017 - 2020 胃粘膜の腸型化における胃レプチンシグナルの役割
2016 - 2019 The complementary research for development of adrenomedullin therapy in inflammatory bowel disease.therapy
2014 - 2017 胃粘膜恒常性維持における胃レプチンシグナルの役割
2011 - 2014 AMPキナーゼが消化管粘膜において細胞増殖および極性形成に果たす役割

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Papers (33)：

Arita S, Ogawa T, Murakami Y, Kinoshita Y, Okazaki M, Inagaki-Ohara K. Dietary Fat-Accelerating Leptin Signaling Promotes Protumorigenic Gastric Environment in Mice. Nutrients. 2019. 11. 9
Arita S, Inagaki-Ohara K. High-fat-diet-induced modulations of leptin signaling and gastric microbiota drive precancerous lesions in the stomach. Nutrition (Burbank, Los Angeles County, Calif.). 2019. 67-68. 110556
Inagaki-Ohara K. Gastric Leptin and Tumorigenesis: Beyond Obesity. International journal of molecular sciences. 2019. 20. 11
Kinoshita Y, Arita S, Murazoe H, Kitamura K, Ashizuka S, Inagaki-Ohara K. Subcutaneously administered adrenomedullin exerts a potent therapeutic effect in a murine model of ulcerative colitis. Human cell. 2018. 32. 1. 12-21
Nishino, Tasuku, Matsunaga, Ryota, Jikihara, Hiroshi, Uchida, Moe, Maeda, Akane, Qi, Guangying, Abe, Takaya, Kiyonari, Hiroshi, Tashiro, Satoshi, Inagaki-Ohara, Kyoko, et al. Antagonizing effect of CLPABP on the function of HuR as a regulator of ARE-containing leptin mRNA stability and the effect of its depletion on obesity in old male mouse. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS. 2016. 1861. 11. 1816-1827

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MISC (28)：

Taeko Dohi, Rei Kawashima, Yuki I. Kawamura, Tomoyuki Oshio, Motomi Yamazaki, Teruki Hagiwara, Toshihiko Okada, Kyoko Inagaki-Ohara, Suzanne Szak, Ping Wu, et al. IL-13 Induces TWEAK-Dependent Activation of TNF-alpha and Intestinal Epithelial Cell Damage -a Pathway Associated With Ulcerative Colitis. GASTROENTEROLOGY. 2012. 142. 5. S346-S347
Kazuo Kitamura, Shinya Ashizuka, Kyoko Inagaki-Ohara, Kenji Kuwasako, Johji Kato, Haruhiko Inatsu. Adrenomedullin treatment reduces intestinal inflammation in mice administered dextran sulphate sodium. ENDOCRINE JOURNAL. 2010. 57. S574-S574
K Inagaki-Ohara, A Sasaki, G Matsuzaki, T Ikeda, M Hotokezaka, K Chijiiwa, M Kubo, H Yoshida, Y Nawa, A Yoshimura. Suppressor of cytokine signalling 1 in lymphocytes regulates the development of intestinal inflammation in mice. GUT. 2006. 55. 2. 212-219
K Inagaki-Ohara, A Sawaguchi, T Suganuma, G Matsuzaki, Y Nawa. Intraepithelial lymphocytes express junctional molecules in murine small intestine. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2005. 331. 4. 977-983
S Yada, N Takamura, K Inagaki-Ohara, MK O'Leary, C Wasem, T Brunner, DR Green, TS Lin, MJ Pinkoski. The role of p53 and Fas in a model of acute murine graft-versus-host disease. JOURNAL OF IMMUNOLOGY. 2005. 174. 3. 1291-1297

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Books (2)：

腸管バリアと寄生虫のせめぎあい
医学のあゆみ 2004
ヘルペスウイルス感染と生体防御
別冊医学のあゆみ 1999

Works (4)：

腸管寄生虫感染による粘膜損傷と修復における腸管上皮間T細胞の役割解明
2004 -
腸管上皮間T細胞による腸管バリア構築機構の解明
2004 -
Regulation of junctional molecules in intestinal epithelial cells during infection with intestinal nematodes
2004 -
Role of intestinal intraepithelial lymphocytes to construct epithelial barrier
2004 -

Education (2)：

Hiroshima University Faculty of Applied Biological Science
Nagoya University

Professional career (1)：

Immunology (Nagoya University)

Work history (5)：

国立国際医療研究センター研究所
National Institute for Physiological Sciences
University of the Ryukyus
University of Miyazaki Faculty of Medicine
九州大学生体防御医学研究所

Association Membership(s) (6)：

JAPAN SOCIETY OF NUTRITION AND FOOD SCIENCE , 日本分子生物学会 , THE PHYSIOLOGICAL SOCIETY OF JAPAN , JAPAN SOCIETY FOR THE STUDY OF OBESITY , Japanese Association for food Immunology , 日本免疫学会

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