INAGAKI-OHARA Kyoko

イナガキキョウコ | INAGAKI-OHARA Kyoko

Affiliation and department：
Job title： Guest Professor

Research field (1)： Immunology

Research keywords (2)：胃がん、消化管免疫、肥満、炎症 , Mucosal Immunology

Research theme for competitive and other funds (12)：

2022 - 2025 Regulatory mechanisms of gastric cancer based on leptin signaling in mice
2017 - 2020 胃粘膜の腸型化における胃レプチンシグナルの役割
2016 - 2019 The complementary research for development of adrenomedullin therapy in inflammatory bowel disease.therapy
2014 - 2017 胃粘膜恒常性維持における胃レプチンシグナルの役割
2011 - 2014 AMPキナーゼが消化管粘膜において細胞増殖および極性形成に果たす役割

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Papers (34)：

Yuta Kinoshita, Seiya Arita, Takumi Ogawa, Ayane Takenouchi, Kyoko Inagaki-Ohara. Augmented leptin-induced trefoil factor 3 expression and epidermal growth factor receptor transactivation differentially influences neoplasia progression in the stomach and colorectum of dietary fat-induced obese mice. Archives of biochemistry and biophysics. 2022. 729. 109379-109379
Arita S, Ogawa T, Murakami Y, Kinoshita Y, Okazaki M, Inagaki-Ohara K. Dietary Fat-Accelerating Leptin Signaling Promotes Protumorigenic Gastric Environment in Mice. Nutrients. 2019. 11. 9
Arita S, Inagaki-Ohara K. High-fat-diet-induced modulations of leptin signaling and gastric microbiota drive precancerous lesions in the stomach. Nutrition (Burbank, Los Angeles County, Calif.). 2019. 67-68. 110556-110556
Inagaki-Ohara K. Gastric Leptin and Tumorigenesis: Beyond Obesity. International journal of molecular sciences. 2019. 20. 11
Kinoshita Y, Arita S, Murazoe H, Kitamura K, Ashizuka S, Inagaki-Ohara K. Subcutaneously administered adrenomedullin exerts a potent therapeutic effect in a murine model of ulcerative colitis. Human cell. 2018. 32. 1. 12-21

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MISC (30)：

Taeko Dohi, Rei Kawashima, Yuki I. Kawamura, Tomoyuki Oshio, Motomi Yamazaki, Teruki Hagiwara, Toshihiko Okada, Kyoko Inagaki-Ohara, Suzanne Szak, Ping Wu, et al. IL-13 Induces TWEAK-Dependent Activation of TNF-alpha and Intestinal Epithelial Cell Damage -a Pathway Associated With Ulcerative Colitis. GASTROENTEROLOGY. 2012. 142. 5. S346-S347
稲垣匡子, 箕越靖彦, 土肥多恵子, 松崎吾朗, 加藤誠也, 吉村昭彦. 消化管上皮細胞特異的SOCS3欠損マウスの胃腫瘍発症におけるレプチン/レプチン受容体の役割. 日本栄養・食糧学会大会講演要旨集. 2012. 66回. 161-161
稲垣匡子, 吉村昭彦, 松崎吾朗, 加藤誠也, 箕越靖彦. 消化管上皮細胞特異的SOCS3欠損マウスの胃癌発症におけるレプチン/レプチン受容体の役割. 肥満研究. 2010. 16. Suppl. 131-131
Kazuo Kitamura, Shinya Ashizuka, Kyoko Inagaki-Ohara, Kenji Kuwasako, Johji Kato, Haruhiko Inatsu. Adrenomedullin treatment reduces intestinal inflammation in mice administered dextran sulphate sodium. ENDOCRINE JOURNAL. 2010. 57. S574-S574
K Inagaki-Ohara, A Sasaki, G Matsuzaki, T Ikeda, M Hotokezaka, K Chijiiwa, M Kubo, H Yoshida, Y Nawa, A Yoshimura. Suppressor of cytokine signalling 1 in lymphocytes regulates the development of intestinal inflammation in mice. GUT. 2006. 55. 2. 212-219

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Books (2)：

Works (4)：

腸管寄生虫感染による粘膜損傷と修復における腸管上皮間T細胞の役割解明
2004 -
腸管上皮間T細胞による腸管バリア構築機構の解明
2004 -
Regulation of junctional molecules in intestinal epithelial cells during infection with intestinal nematodes
2004 -
Role of intestinal intraepithelial lymphocytes to construct epithelial barrier
2004 -

Education (2)：

Professional career (1)：

Work history (6)：

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Association Membership(s) (4)：

日本分子生物学会 , JAPAN SOCIETY FOR THE STUDY OF OBESITY , Japanese Association for food Immunology , 日本免疫学会

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