Rchr
J-GLOBAL ID：200901087161371013
Update date: Sep. 10, 2024
Sakurai Yoshinori
サクライ ヨシノリ | Sakurai Yoshinori
Affiliation and department：
Job title：
Associate Professor
Research field (1)：
Nuclear engineering
Research keywords (2)：
原子力学
, Nuclear power Science
Research theme for competitive and other funds (42)：
- 2022 - 2025 Development of the Direct Observation Method of Boron-dose Distribution for QA in BNCT
- 2024 - 2025 Characterisation of semiconductor detector in neutron irradiation field
- 2020 - 2023 Methodology for 2 dimensional in-situ measurement of quality and intensity of BNCT beam
- 2020 - 2023 ホウ素中性子捕捉療法における中性子ビーム強度変調システムの開発
- 2019 - 2022 Research on irradiation methods and quality assurance that can freely change the treatment depth and region in BNCT
- 2016 - 2019 Investigation of 124Sb-Be neutron source for BNCT
- 2016 - 2019 Beam-profile measurement method using radiation-induced coloration in irradiation field for boron neutron capture therapy
- 2016 - 2019 Accuracy improvement for dose and beam-quality estimation of irradiation field for boron neutron capture therapy using dual phantom technique
- 2016 - 2019 Development of Current Measurement SPECT for the Estimation of Gamma-ray Energy Distribution in Boron Neutron Capture Therapy
- 2016 - 2019 Development of simple quick and high-precision determination method of optimum irradiation position and a deviation detection device of irradiation position for BNCT
- 2015 - 2018 Multilateral approach toward realization of next generation boron neutron capture therapy
- 2014 - 2018 Development of freely deformable neutron shield for boron neutron capture therapy
- 2014 - 2018 A study of the dose evaluation using three-dimensional gel dosimeter for Boron-Neutron Capture Therapy
- 2014 - 2018 Quality assurance of 3 dimensional distribution of 4 beam components of neutron capture therapy - measurement with gel detector -
- 2013 - 2018 Establishment of adaptive criteria and protocol for accelerator-based BNCT
- 2013 - 2017 Study of three-dimensional dosimetry for boron neutron capture therapy
- 2013 - 2017 Development of three dimensional dose evaluation system using prompt gamma-ray for boron neutron capture therapy
- 2012 - 2015 Novel quality assurance of 2 dimensional beam components using enhanced planar detector
- 2010 - 2012 Beam-profile monitor system using gas activation for boron neutron capture therapy
- 2005 - 2009 Basic study on cancer cell selective radiotherapy by particle beam
- 2006 - 2007 Analysis of the effect of reduced dose rate and fractionated irradiation, including the effectoniniraturnor quiescent cells
- 2004 - 2005 The significance of vascular targeting agents as chemotherapeutic drugs for controlling solid tumors.
- 2004 - 2005 Studies about Application of BNCT for Head and Neck Malignancies
- 2003 - 2005 ホウ素中性子捕捉療法における医療照射時下線量評価統合システムの構築
- 2000 - 2004 X線低感受性腫瘍に対する中性子捕捉療法の基礎研究
- 2002 - 2003 Studies about application of BNCT for human oral squamous cell carcinoma
- 2001 - 2003 Development of a new type proton irradiation system built in a rotating gantry
- 2000 - 2001 中性子照射場での生体組織に対する吸収線量評価手法の改善に関する基礎研究
- 1999 - 1999 熱・熱外中性子捕捉反応を利用した深在性放射線抵抗性腫瘍の治療に関する基礎研究
- 1998 - 1999 Mutagenic effects at HPRT locus in Chinese Hamster Ovary(CHO)cells induced by epi-thermal and thermal neutrons
- 1997 - 1999 Development of thermal/epithermal neutron capture therapy system for X-ray refractory tumors
- 1998 - 1998 熱・熱外中性子捕捉反応を利用した深在性放射線抵抗性腫瘍の治療に関する基礎研究
- 1997 - 1997 腫瘍内休止期細胞への効果を加味した中性子捕促化合物の効果投与様式の探究
- 1997 - 1997 熱・熱外中性子捕捉反応を利用した深在性放射線抵抗性腫瘍の治療に関する基礎研究
- 1996 - 1997 Study on Hyper Thermal Neutron Irradiation Field for Neutron Capture Therapy
- 1995 - 1997 Study on Detectors for On-line Measurement and estimation of absorbed energy using SPECT system in Neutron Capture Therapy
- 線量評価法に関する研究
- 中性子照射場に関する研究
- 中性子捕捉療法に関する物理工学的研究
- Study on Dose Estimation Methods
- Study on Neutron Irradiation Field
- Study on Physics and Engineering for Neutron Capture Therapy
Show all
Papers (568)：
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Takuya Fujimoto, Osamu Yamasaki, Noriyuki Kanehira, Hirokazu Matsushita, Yoshinori Sakurai, Naoya Kenmotsu, Ryo Mizuta, Natsuko Kondo, Takushi Takata, Mizuki Kitamatsu, et al. Overcoming immunotherapy resistance and inducing abscopal effects with boron neutron immunotherapy (B-NIT). Cancer science. 2024
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Riku Kawasaki, Ayano Oshige, Nanami Kono, Keita Yamana, Hidetoshi Hirano, Yamato Miura, Ryuji Yorioka, Kaori Bando, Anri Tabata, Naoki Yasukawa, et al. Extracellular Vesicles Comprising Carborane Prepared by a Host Exchanging Reaction as a Boron Carrier for Boron Neutron Capture Therapy. ACS applied materials & interfaces. 2024
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Ryosuke Narita, Shin-ichiro Hayashi, Yoshinori Sakurai. A characterization of LCV micelle gel dosimeters for boron neutron capture therapy. Journal of Physics: Conference Series. 2024. 2799. 1. 012009-012009
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藤本 卓也, 神谷 伸彦, 南 裕介, 櫻井 良憲, 圓尾 明弘, 八尋 俊輔, 藤田 郁夫, 秋末 敏宏, 黒田 良祐, 鈴木 実. 肉腫治療の次の一手 癌の骨浸潤に対してホウ素中性子捕捉療法(BNCT)は可能か. 日本整形外科学会雑誌. 2024. 98. 6. S1487-S1487
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Takuya Fujimoto, Fuminori Teraishi, Noriyuki Kanehira, Tomoyuki Tajima, Yoshinori Sakurai, Natsuko Kondo, Masahiro Yamagami, Atsushi Kuwada, Akira Morihara, Mizuki Kitamatsu, et al. BNCT pancreatic cancer treatment strategy with glucose-conjugated boron drug. Biomaterials. 2024. 309. 122605-122605
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MISC (544)：
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平野英寿, 河崎陸, 山名啓太, 真田悠生, 坂東香里, 田畑杏梨, 高田卓志, 櫻井良憲, 鈴木実, 樽谷直紀, et al. Development and evaluation of hybrid nanogels composing of carborane-containing polysaccharides and hydrophobic boron oxide nanoparticles for BNCT. 日本バイオマテリアル学会大会予稿集(Web). 2023. 45th
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真田悠生, 高田卓志, 田中浩基, 櫻井良憲, 渡邉翼. Attempts to enhance the anti-tumor effects of BNCT by targeting the tumor microenvironment. KURNS-EKR (Web). 2023. 17
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河崎陸, 平野英寿, 山名啓太, 真田悠生, 坂東香里, 田畑杏梨, 櫻井良憲, 田中浩基, 鈴木実, 澤田晋一, et al. Development of Hybrid Nanogels with Highly Integrated Boron Oxide Nanoparticle and Evaluation of Their Biofunction. ホスト-ゲスト・超分子化学シンポジウム講演要旨集. 2023. 20th
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小林奈央, 近藤夏子, 櫻井良憲, 鈴木実, 山口真一, 池川雅哉. 3D Imaging of Metabolic Effects of the Brains from Murine Models of Glioma Treated with Boron Neutron Capture Therapy (BNCT). 質量分析総合討論会講演要旨集. 2023. 71st
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松林錦, 高田卓志, 呼尚徳, 笹木彬礼, 武川哲也, 菅啓大, 櫻井良憲, 田中浩基. Gamma dose evaluation method with BeO OSLD in BNCT. KURNS-EKR (Web). 2023. 17
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Patents (3)：
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中性子線照射装置
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中性子線照射装置
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中性子線遮蔽材料
Books (5)：
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医学物理教科書シリーズ:放射線治療物理学,編著:荒木不次男、他
国際文献社 2016
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医学物理学教科書シリーズ:放射線計測学,編著:納冨昭弘
国際文献社 2015
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原子力・量子・核融合事典,第?分冊,量子ビームと放射線医療,編集:工藤和彦,他
丸善出版 2014
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医学物理士のための医学物理講習会資料2014(JBMP2014) ,監修:医学物理士認定機構教育委員会
一般財団法人医学物理士認定機構 2014
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BNCT基礎から臨床応用まで”-BNCTを用いて治療にかかわる人のためのテキスト-,監修:財団法人医用原子力技術研究振興財団中性子補足療法推進特別委員会,日本中性子補足療法学会
財団法人医用原子力技術研究振興財団 2011
Lectures and oral presentations (4)：
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Advances in BNCT at Kyoto University Research Reactor Institute -from reactor-based BNCT to accelerator-based BNCT
(the 7th Korea-Japan Joint Meeting on Medical Physics, Symposium-3-2 (2014.09.25-27) Busan 2014)
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硼素中性子捕捉療法における医学物理学
(第3回JBMP放射線治療品質管理・医学物理講習会, 教育講演,(2014.09.13) 吹田 2014)
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硼素中性子捕捉療法の新展開-原子炉から加速器へ
(量子理工学教育研究センター第13回公開シンポジウム,(2012.10.19) 宇治 2012)
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BNCT用中性子照射場:原子炉から加速器へ
(日本放射線腫瘍学会 第24回学術大会 S4-6 (2011.11.17-19) 神戸 2011)
Education (4)：
- - 1995 Kyoto University
- - 1995 Kyoto University Graduate School, Division of Engineering Nuclear Engineering
- - 1990 Kyoto University Faculty of Engineering
- - 1990 Kyoto University Faculty of Engineering Nuclear Engineering
Professional career (1)：
- Doctor of Engineering (Kyoto University)
Work history (5)：
- 1995 - 1997 Kyoto University Research Reactor Institute
- 1995 - 1997 Research Associate, Research Reactor Institate,
- 1997 - - 京都大学原子炉実験所 助手
- 1997 - - Research Associate,Research Reactor Institate,
- Kyoto University
Committee career (1)：
Association Membership(s) (6)：
日本放射線腫瘍学会
, 応用物理学会放射線分科会
, 日本放射線影響学会
, 国際中性子捕捉療法協会(International Society for Neutron Capture Therapy)
, 日本医学物理学会
, 日本原子力学会
