Ijuin Takeshi

イジュウインタケシ | Ijuin Takeshi

Affiliation and department：
Job title： Assistant Professor

Research field (1)： Medical biochemistry

Research keywords (2)： Lipid Biochemistry , Cellular Biology

Research theme for competitive and other funds (16)：

2019 - 2022 Analysis of the onset mechanism of Marinesco Sjogren's syndrome starting from phosphoinositide metabolism disorder
2018 - 2021 Analysis of molecular mechanism underlying S1P signal-mediated exosome release
2018 - 2020 Analysis on pathogenesis of Parkinson's disease through S1P signaling
2016 - 2020 Regulation of ER stress response by phopholipids
2016 - 2019 リン脂質を介した新しい小胞体ストレス応答メカニズムの解明

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Papers (40)：

Taro Okada, Susumu Nishida, Lifang Zhang, Nesma Nabil Ibrahim Mohamed, Tianyou Wang, Takeshi Ijuin, Taketoshi Kajimoto, Shun-Ichi Nakamura. Constitutive activation of S1P receptors at the trans-Golgi network is required for surface transport carrier formation. iScience. 2021. 24. 11. 103351-103351
Shubi Ambwene Matovelo, Lifang Zhang, Nesma Nabil Ibrahim Mohamed, Taketoshi Kajimoto, Takeshi Ijuin, Taro Okada, Shun-Ichi Nakamura. Involvement of Receptor-Mediated S1P Signaling in EGF-Induced Macropinocytosis in COS7 Cells. The Kobe journal of medical sciences. 2020. 66. 3. E94-E101
Takeshi Ijuin. Phosphoinositide phosphatases in cancer cell dynamics-Beyond PI3K and PTEN. SEMINARS IN CANCER BIOLOGY. 2019. 59. 50-65
Shaymaa Mohamed Mohamed Badawy, Taro Okada, Taketoshi Kajimoto, Mitsuhiro Hirase, Shubi Ambwene Matovelo, Shunsuke Nakamura, Daisuke Yoshida, Takeshi Ijuin, Shun-ichi Nakamura. Extracellular -synuclein drives sphingosine 1-phosphate receptor subtype 1 out of lipid rafts, leading to impaired inhibitory G-protein signaling. JOURNAL OF BIOLOGICAL CHEMISTRY. 2018. 293. 21. 8208-8216
Badawy SMM, Okada T, Kajimoto T, Hirase M, Matovelo SA, Nakamura S, Yoshida D, Ijuin T, Nakamura S. Extracellular α-synuclein drives sphingosine 1-phosphate receptor subtype 1 out of lipid rafts, leading to impaired inhibitory G protein signaling. J Biol Chem. 2018. 293. 21. 8208-8216

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MISC (41)：

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Lectures and oral presentations (25)：

Phosphoinositide phosphatase INPP5K/SKIP controls myogenesis through regulation of cell surface PS exposure
(2019)
ホスホイノシタイドホスファターゼINPP5K(SKIP)による小胞体とER-PM junctionの形態維持と細胞の恒常性の維持
(第9回日本プロテインホスファターゼ研究集会 2019)
タイトルホスホイノシタイドホスファターゼSKIPによるPSの細胞表面への表出と筋芽細胞融合の制御
(第61回日本脂質生化学会 2019)
Roles of Phosphoinositide 5-Phosphatase SHIP2 in focal adhesion turnover depend on cancer cell types
(13th Workshop on Frontiers in Phosphatase Research 2018)
エクソソームへの積荷ソーティングにおける三量体Gタンパク質βγサブユニットシグナリングの役割
(第91回日本生化学会大会 2018)

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Education (1)：

- 2000 The University of Tokyo Graduate School of Science Department of Biophysics and Biochemistry

Association Membership(s) (7)：

日本プロテインホスファターゼ研究会 , 日本筋学会 , 日本癌学会 , 日本細胞生物学会 , 日本脂質生化学会 , 日本分子生物学会 , 日本生化学会

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