2020 - 2023 Mechanism of predicting the effects of immune checkpoint inhibitors based on the diversity of cancer-associated fibroblasts
2020 - 2023 がんの線維化におけるMeflinの機能解析と新規治療法の開発研究
2019 - 2023 Dynamic regulation of cancer associated fibroblast via functional RNA as a novel therapeutic target for pancreas cancer
2018 - 2021 Identification of molecular mechanisms that regulate the proliferation-migration dichotomy of cancer cells
2017 - 2020 Analysis of the role of mesenchymal stem cell marker Meflin in kidney fibrosis
2017 - 2020 Analysis of the role of mesenchymal stem cell marker Meflin in glomerulonephritis
2014 - 2019 Functional analysis of Girdin family proteins in psyco-neurological disease and cancer
2015 - 2018 Mechanisms and significance of collective cancer cell migration mediated by cadherin-specific endocytosis
2014 - 2016 Identification of molecular mechanisms that regulate collective invasion of cancer cells
2013 - 2016 Investigation of pathogenesis of mesial temporal epilepsy using monogenic mouse model
2013 - 2016 Investigation of discrimination and activation of Dynamin 2 GTPase by Girdin
2014 - 2015 Girdinファミリー分子の機能と精神神経疾患・がんの病態形成における役割
2012 - 2015 Mechanisms for selective endocytosis and its involvement in the pathogenesis of cancer and psychiatric disorders
2010 - 2015 Roles of Girdin phosphorylation by Akt kinase in human diseases
2011 - 2014 Molecular mechanisms of postnatal angiogenesis and neurogenesis
2011 - 2013 細胞の集団的移動と接触阻害の分子メカニズムの解明
2009 - 2011 Molecular mechanisms for neurogenesis and psychiatric dysfunction in postnatal and adult periods
2007 - 2010 Physiological functions of the Akt substrate Girdin and its family proteins and their roles in pathogenesis
2006 - 2008 Roles of the novel Akt substrate Girdin and its family of proteins in development and tumor protression
2003 - 2005 腎臓と神経の発生及び再生に関与する遺伝子の探索及びその機能の解明
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Papers (278):
Yuki Sonoda, Masataka Hirasaki, Yoko Usami, Tomoaki Torigoe, Tomonori Kawasaki, Nobuyuki Suzuki, Yukihiro Shiraki, Atsushi Enomoto, Hiroki Imada, Yasutaka Baba. Pulmonary metastases of a renal angiomyolipoma: A case report, with whole-exome sequencing analysis. Radiology case reports. 2024. 19. 11. 4963-4969
Satoya Yoshida, Tatsuya Yoshida, Kohei Inukai, Katsuhiro Kato, Yoshimitsu Yura, Tomoki Hattori, Atsushi Enomoto, Koji Ohashi, Takahiro Okumura, Noriyuki Ouchi, et al. Protein kinase N promotes cardiac fibrosis in heart failure by fibroblast-to-myofibroblast conversion. Nature communications. 2024. 15. 1. 7638-7638
Toshikazu Ishihara, Katsuhiro Kato, Kotaro Matsumoto, Miyako Tanaka, Akitoshi Hara, Yukihiro Shiraki, Hidenori Morisaki, Yuya Urano, Ryota Ando, Kisuke Ito, et al. Meflin/ISLR is a marker of adipose stem and progenitor cells in mice and humans that suppresses white adipose tissue remodeling and fibrosis. Genes to cells : devoted to molecular & cellular mechanisms. 2024
Hiroki Kobayashi, Tadashi Iida, Yosuke Ochiai, Ermanno Malagola, Xiaofei Zhi, Ruth A White, Jin Qian, Feijing Wu, Quin T Waterbury, Ruhong Tu, et al. Neuro-mesenchymal interaction mediated by a β2 adrenergic-nerve growth factor feedforward loop promotes colorectal cancer progression. Cancer discovery. 2024
Rikito Tatsuno, Yoshihiro Komohara, Cheng Pan, Tomonori Kawasaki, Atsushi Enomoto, Takahiro Jubashi, Hiroyuki Kono, Masanori Wako, Tomoyuki Ashizawa, Hirotaka Haro, et al. Surface Markers and Chemokines/Cytokines of Tumor-Associated Macrophages in Osteosarcoma and Other Carcinoma Microenviornments-Contradictions and Comparisons. Cancers. 2024. 16. 16
2013 - 日本腎臓学会 ベストサイテーション賞 Roles of organic anion transporters (OATs) and a urate transporter (URAT1) in the pathophysiology of human disease (Clin Exp Nephrol. 9:195-205, 2005)
日本メカノバイオロジー学会
, THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
, JAPAN SOCIETY FOR CELL BIOLOGY
, THE JAPANESE SOCIETY OF PATHOLOGY
, THE JAPANESE CANCER ASSOCIATION