Rchr
J-GLOBAL ID：200901089139977563
Update date: Sep. 09, 2024
Ichihara Sahoko
イチハラ サホコ | Ichihara Sahoko
Affiliation and department：
Job title：
Professor
Homepage URL (1)：
http://www.jichi.ac.jp/enviro/hp/index.html
Research field (3)：
Hygiene and public health (laboratory)
, Hygiene and public health (non-laboratory)
, Cardiology
Research keywords (6)：
環境医学
, 産業医学
, 心毒性学
, 循環器病学
, Environmental Medicine
, Cardiac toxicology
Research theme for competitive and other funds (31)：
- 2023 - 2027 Risk assessment of atmospheric microplastics for human health
- 2022 - 2025 Elucidation of the pathogenic mechanism of lifestyle-related diseases by transomics analysis with a focus on the proteome
- 2021 - 2024 A validation epidemiological study of a comprehensive risk algorithm for lifestyle-related diseases in a community-based population
- 2022 - 2023 Mechanism of arsenic-induced vascular endothelial dysfunction
- 2020 - 2023 Mechanism of inflammatory response on digestive tract by plastic nanoparticles
- 2020 - 2023 Development of the evaluation system for cardiovascular effects of fiber materials
- 2021 - 2022 Mechanism of arsenic-induced vascular endothelial dysfunction
- 2017 - 2020 Endocytosis-independent membrane fusion peptides for cancer stem cell drug delivery
- 2016 - 2019 Prediction of the genetic and epigenetic risks associated with lifestyle-related diseases in the population-based confirmatory factor analysis
- 2014 - 2019 Epidemiological study on the effects of industrial nanomaterials on cardiovascular system
- 2015 - 2018 Elucidation of adiponectin expression pathway based on the co-expression network and epigenome data analysis
- 2015 - 2018 Inflammatory responses triggered by inflammasome activation after exposure to carbon nanotubes
- 2014 - 2017 Investigation on the effects of environmental stress on the cardiovascular system
- 2013 - 2016 Construction of an epigenetic epidemiology database for a population cohort
- 2013 - 2015 Elucidation of the expression pathway of adiponectin based on the integrated data analysis using epigenetic data
- 2012 - 2015 Prediction of the genetic and epigenetic risk associated with lifestyle-relatied diseases in the population-based confirmatory factor analysis
- 2011 - 2013 Role of neurogenesis in mechanism of chronic or late-onset toxicity of environmental chemicals to the central nervous system
- 2010 - 2012 血液脳関門破綻と血管内皮障害とに共通する接着因子の作用メカニズムの解明
- 2010 - 2012 Study on oxidative stress and glial activation explaining demyelination in the central nervous system induced by alternative to freons
- 2011 - 2011 ナノ酸化金属の循環器系への影響に関する疫学調査
- 2009 - 2011 Investigation on toxicity of 1-bromopropane to central nervous system and hematopoetic function in humans
- 2008 - 2010 Physiological status depending on particle size in workers at the nano-handling factor
- 2007 - 2009 Analysis of molecular and cellular targets in neurotoxicity of alternatives to ozone-depleting substances and establishment of biomarkers for the central nervous toxicity
- 2007 - 2008 メタボリック症候群の病態解明と予防法・治療法の開発
- 2006 - 2008 A role for the aryl hydrocarbon receptor in regulation of ischemia-induced angiogenesis
- 2006 - 2008 Development of the personalized prevention system for ischemic stroke by a genome-wide association study
- 2005 - 2008 Study on dose-dependency of the central nervous system toxicity of 1-bromopropane in humans
- 2003 - 2007 喫煙による循環器系への影響
- 2005 - 環境化学物質の心血管系システムへの影響
- 2004 - メタボリック症候群における心血管障害の機序の解明
- Cardiovascular diseases and oxidative stress
Show all
Papers (159)：
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Yuji Fujitani, Akihiko Ikegami, Kouta Morikawa, Jun Kumoi, Takeo Yano, Atsushi Watanabe, Ai Shiono, Chuichi Watanabe, Norio Teramae, Gaku Ichihara, et al. Quantitative assessment of nano-plastic aerosol particles emitted during machining of carbon fiber reinforced plastic. Journal of hazardous materials. 2024. 467. 133679-133679
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Ryoya Takizawa, Akihiko Ikegami, Cai Zong, Syun Nemoto, Yuki Kitamura, Nathan Mise, Gaku Ichihara, Sahoko Ichihara. Effect of differently coated titanium dioxide nanoparticles on the lung in wild-type and Nrf2 null mice. Fundamental Toxicological Sciences. 2024. 11. 3. 109-121
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Alzahraa Fergany, Cai Zong, Frederick Adams Ekuban, Bin Wu, Satoshi Ueha, Shigeyuki Shichino, Kouji Matsushima, Yoichiro Iwakura, Sahoko Ichihara, Gaku Ichihara. Transcriptome analysis of the cerebral cortex of acrylamide-exposed wild-type and IL-1β-knockout mice. Archives of toxicology. 2023
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Walaa Slouma Hamouda Abd El Naby, Cai Zong, Alzahraa Fergany, Frederick Adams Ekuban, Saleh Ahmed, Yousra Reda, Harue Sato, Sahoko Ichihara, Natsuko Kubota, Shinya Yanagita, et al. Exposure to Benzo[a]pyrene Decreases Noradrenergic and Serotonergic Axons in Hippocampus of Mouse Brain. International journal of molecular sciences. 2023. 24. 12
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Bo Wang, Boxuan Liang, Yuji Huang, Zhiming Li, Bingli Zhang, Jiaxin Du, Rongyi Ye, Hongyi Xian, Yanhong Deng, Jiancheng Xiu, et al. Long-Chain Acyl Carnitines Aggravate Polystyrene Nanoplastics-Induced Atherosclerosis by Upregulating MARCO. ADVANCED SCIENCE. 2023
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MISC (91)：
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Akihiko Ikegami, Jun Kumoi, Yuji Fujitani, Takeo Yano, Gaku Ichihara, Sahoko Ichihara. Debris from carbon fiber reinforced plastics in an occupational setting. SAFETY AND HEALTH AT WORK. 2022. 13. S224-S224
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長嶋大地, 黄振烈, 市原佐保子, 及川伸二, 市原学, 山野優子. 中枢神経毒性を有する親電子性物質曝露時の影響マーカーの探索. 産業衛生学雑誌. 2019. 61. 440
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X. Zhang, K. Morikawa, Y. Mori, C. Zong, L. Zhang, E. Garner, C. Huang, W. Wu, J. Chang, D. Nagashima, et al. Proteomic Analysis of Liver Proteins of Mice Exposed to 1,2-dichloropropane. Society of Toxicology 58th Annual Meeting (SOT2018). 2019
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EKUBAN Frederick, ZONG Cai, 森川浩太, 瀧川円賀, 櫻井敏博, 市原佐保子, 大迫誠一郎, 市原学. Nrf2の欠損はアクリルアミド神経毒性に対する感受性を増強する. 衛生薬学・環境トキシコロジー講演要旨集. 2019. 2019
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Sahoko Ichihara, Yuka Suzuki, Yu Iwase, Kiyora Izuoka, Cai Zong, Gaku Ichihara. Carbon Nanotubes Promotes Atherosclerosis Due to Enhancing Inflammatory Responses Triggered by Inflammasome Activation. CIRCULATION. 2018. 138
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Education (2)：
- - 2001 名古屋大学大学院 医学研究科
- - 1990 Nagoya University School of Medicine
Professional career (1)：
- MD, PhD (Nagoya University)
Work history (3)：
- 2017/04 - 現在 Jichi Medical University School of Medicine
- 2009/04 - 2017/03 Mie University Graduate School of Regional Innovation Studies
- 2004/01 - 2009/03 Mie University Life Science Research Center
Association Membership(s) (6)：
THE JAPANESE SOCIETY FOR HYGIENE
, JAPAN SOCIETY FOR OCCUPATIONAL HEALTH
, THE JAPANESE SOCIETY OF TOXICOLOGY
, 日本人類遺伝学会
, 日本内科学会
, 日本循環器学会
